decreased circulating interleukin-10 level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction in the amount in the blood of a cytokine produced by a variety of cell types, including T-cells, monocytes, dendritic cells and epithelial cells that exerts a variety of effects on immunoregulation and inflammation (Mammalian Phenotype Ontology, MP_0008594)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008594
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Genes

5 gene mutations causing the decreased circulating interleukin-10 level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CD19 CD19 molecule
IL10 interleukin 10
LDLR low density lipoprotein receptor
MMP9 matrix metallopeptidase 9
MYD88 myeloid differentiation primary response 88