|Dataset||MPO Gene-Phenotype Associations|
|Category||disease or phenotype associations|
|Description||reduction in the amount in the blood of an interleukin-1 subtype that occurs as a membrane-bound pro-protein form that is cleaved by proteases to form a secreted mature form; both membrane-bound and secreted forms of interleukin-1alpha are biologically active (Mammalian Phenotype Ontology, MP_0008639)|
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4 gene mutations causing the decreased circulating interleukin-1 alpha level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.