decitabine-920 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the decitabine-920 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGXT alanine-glyoxylate aminotransferase
ANKRD36 ankyrin repeat domain 36
APAF1 apoptotic peptidase activating factor 1
APOE apolipoprotein E
APOM apolipoprotein M
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARMCX4 armadillo repeat containing, X-linked 4
ATRX alpha thalassemia/mental retardation syndrome X-linked
BTN3A3 butyrophilin, subfamily 3, member A3
C9ORF40 chromosome 9 open reading frame 40
CBX8 chromobox homolog 8
CCP110 centriolar coiled coil protein 110kDa
CFLAR CASP8 and FADD-like apoptosis regulator
CLEC10A C-type lectin domain family 10, member A
COL3A1 collagen, type III, alpha 1
COMP cartilage oligomeric matrix protein
CPPED1 calcineurin-like phosphoesterase domain containing 1
CSHL1 chorionic somatomammotropin hormone-like 1
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CTSZ cathepsin Z
EGR1 early growth response 1
EIF5A2 eukaryotic translation initiation factor 5A2
EPHB2 EPH receptor B2
ERP44 endoplasmic reticulum protein 44
ESR1 estrogen receptor 1
FAM212B family with sequence similarity 212, member B
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FGF23 fibroblast growth factor 23
FILIP1L filamin A interacting protein 1-like
FLJ21369 uncharacterized protein FLJ21369
GLUD2 glutamate dehydrogenase 2
GREB1L growth regulation by estrogen in breast cancer-like
GSPT1 G1 to S phase transition 1
HFE hemochromatosis
HIST1H3C histone cluster 1, H3c
HIST1H4H histone cluster 1, H4h
HMGN5 high mobility group nucleosome binding domain 5
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IL12RB1 interleukin 12 receptor, beta 1
KCTD7 potassium channel tetramerization domain containing 7
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRT12 keratin 12, type I
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LRRC40 leucine rich repeat containing 40
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAP1A microtubule-associated protein 1A
MED25 mediator complex subunit 25
NCSTN nicastrin
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NPPB natriuretic peptide B
OAZ3 ornithine decarboxylase antizyme 3
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OSGIN2 oxidative stress induced growth inhibitor family member 2
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRKD3 protein kinase D3
PRR14L proline rich 14-like
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PVR poliovirus receptor
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF6 ring finger protein (C3H2C3 type) 6
RPLP2 ribosomal protein, large, P2
RPS2 ribosomal protein S2
RPS28 ribosomal protein S28
RRAGB Ras-related GTP binding B
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RUFY2 RUN and FYVE domain containing 2
SCAI suppressor of cancer cell invasion
SCAMP1 secretory carrier membrane protein 1
SCN2B sodium channel, voltage gated, type II beta subunit
SCUBE3 signal peptide, CUB domain, EGF-like 3
SDC2 syndecan 2
SIGLEC15 sialic acid binding Ig-like lectin 15
SIX1 SIX homeobox 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SOCS1 suppressor of cytokine signaling 1
SRSF11 serine/arginine-rich splicing factor 11
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
STK17B serine/threonine kinase 17b
STS steroid sulfatase (microsomal), isozyme S
TMPRSS4 transmembrane protease, serine 4
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TREX1 three prime repair exonuclease 1
TRIO trio Rho guanine nucleotide exchange factor
TUBA3C tubulin, alpha 3c
UNC93A unc-93 homolog A (C. elegans)
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VAV2 vav 2 guanine nucleotide exchange factor
WDR1 WD repeat domain 1
ZBTB33 zinc finger and BTB domain containing 33
ZNF223 zinc finger protein 223
ZNF814 zinc finger protein 814

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ANKRD40 ankyrin repeat domain 40
ANPEP alanyl (membrane) aminopeptidase
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ASPHD1 aspartate beta-hydroxylase domain containing 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BAHCC1 BAH domain and coiled-coil containing 1
BBC3 BCL2 binding component 3
BPHL biphenyl hydrolase-like (serine hydrolase)
CCDC170 coiled-coil domain containing 170
CCNO cyclin O
CENPO centromere protein O
CLASRP CLK4-associating serine/arginine rich protein
CLSPN claspin
CORT cortistatin
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DMTN dematin actin binding protein
DSCAM Down syndrome cell adhesion molecule
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ETAA1 Ewing tumor-associated antigen 1
FKBP10 FK506 binding protein 10, 65 kDa
FLT4 fms-related tyrosine kinase 4
FUZ fuzzy planar cell polarity protein
GMEB1 glucocorticoid modulatory element binding protein 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUSBP3 glucuronidase, beta pseudogene 3
H2AFY2 H2A histone family, member Y2
HDAC5 histone deacetylase 5
HYI hydroxypyruvate isomerase (putative)
IFT22 intraflagellar transport 22
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KIAA0319L KIAA0319-like
LHFPL2 lipoma HMGIC fusion partner-like 2
LIME1 Lck interacting transmembrane adaptor 1
LMNB2 lamin B2
LOC730101 uncharacterized LOC730101
LY6D lymphocyte antigen 6 complex, locus D
MAP7D1 MAP7 domain containing 1
MAP9 microtubule-associated protein 9
MED15 mediator complex subunit 15
NPIPB15 nuclear pore complex interacting protein family, member B15
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PDZRN3 PDZ domain containing ring finger 3
PGP phosphoglycolate phosphatase
POLH polymerase (DNA directed), eta
POLL polymerase (DNA directed), lambda
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RANBP17 RAN binding protein 17
RBL1 retinoblastoma-like 1
RBM42 RNA binding motif protein 42
RBM6 RNA binding motif protein 6
REPS2 RALBP1 associated Eps domain containing 2
RFTN1 raftlin, lipid raft linker 1
RNF43 ring finger protein 43
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RSF1 remodeling and spacing factor 1
SAMD9 sterile alpha motif domain containing 9
SCGB2A2 secretoglobin, family 2A, member 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SH2D4A SH2 domain containing 4A
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC17A2 solute carrier family 17, member 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC41A3 solute carrier family 41, member 3
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SUN2 Sad1 and UNC84 domain containing 2
SYCP2 synaptonemal complex protein 2
SYT17 synaptotagmin XVII
TAOK3 TAO kinase 3
TMEM104 transmembrane protein 104
TMEM121 transmembrane protein 121
TPCN1 two pore segment channel 1
USP6NL USP6 N-terminal like
VGF VGF nerve growth factor inducible
WDR19 WD repeat domain 19
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZNF180 zinc finger protein 180
ZNF34 zinc finger protein 34
ZNF510 zinc finger protein 510
ZNF74 zinc finger protein 74
ZNF787 zinc finger protein 787
ZNF85 zinc finger protein 85