decamethonium bromide-4094 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the decamethonium bromide-4094 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM19 ADAM metallopeptidase domain 19
AGTR2 angiotensin II receptor, type 2
AIF1 allograft inflammatory factor 1
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
APP amyloid beta (A4) precursor protein
ARSA arylsulfatase A
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
AVPR2 arginine vasopressin receptor 2
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BMP8A bone morphogenetic protein 8a
BST1 bone marrow stromal cell antigen 1
C17ORF53 chromosome 17 open reading frame 53
C8A complement component 8, alpha polypeptide
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CLCN4 chloride channel, voltage-sensitive 4
COMMD4 COMM domain containing 4
CORO1A coronin, actin binding protein, 1A
CRTC1 CREB regulated transcription coactivator 1
CUBN cubilin (intrinsic factor-cobalamin receptor)
CXCR2 chemokine (C-X-C motif) receptor 2
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
CYTH1 cytohesin 1
DCAF11 DDB1 and CUL4 associated factor 11
DPT dermatopontin
DSCC1 DNA replication and sister chromatid cohesion 1
ELOVL5 ELOVL fatty acid elongase 5
EPAS1 endothelial PAS domain protein 1
ERC2-IT1 ERC2 intronic transcript 1
EXOSC1 exosome component 1
FCAR Fc fragment of IgA receptor
FGF5 fibroblast growth factor 5
FLT4 fms-related tyrosine kinase 4
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GAS7 growth arrest-specific 7
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GOLGA8A golgin A8 family, member A
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPX5 glutathione peroxidase 5
HAPLN1 hyaluronan and proteoglycan link protein 1
HOXA7 homeobox A7
HOXD13 homeobox D13
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
JAG1 jagged 1
KANK3 KN motif and ankyrin repeat domains 3
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KLK2 kallikrein-related peptidase 2
LGSN lengsin, lens protein with glutamine synthetase domain
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LINC00574 long intergenic non-protein coding RNA 574
LTBP4 latent transforming growth factor beta binding protein 4
MARK2 MAP/microtubule affinity-regulating kinase 2
MBD2 methyl-CpG binding domain protein 2
MKL1 megakaryoblastic leukemia (translocation) 1
MOBP myelin-associated oligodendrocyte basic protein
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTMR3 myotubularin related protein 3
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
OLFM1 olfactomedin 1
PAX2 paired box 2
PCDH11Y protocadherin 11 Y-linked
PDE4C phosphodiesterase 4C, cAMP-specific
PDLIM3 PDZ and LIM domain 3
PHKG1 phosphorylase kinase, gamma 1 (muscle)
PICALM phosphatidylinositol binding clathrin assembly protein
PLCH1 phospholipase C, eta 1
PRB3 proline-rich protein BstNI subfamily 3
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RBMS3 RNA binding motif, single stranded interacting protein 3
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RUNDC3A RUN domain containing 3A
SCN10A sodium channel, voltage gated, type X alpha subunit
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SGSM2 small G protein signaling modulator 2
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNED1 sushi, nidogen and EGF-like domains 1
SOGA1 suppressor of glucose, autophagy associated 1
SOX2 SRY (sex determining region Y)-box 2
TARP TCR gamma alternate reading frame protein
TBX2 T-box 2
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TMPRSS6 transmembrane protease, serine 6
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TP63 tumor protein p63
TRIM29 tripartite motif containing 29
TRIM3 tripartite motif containing 3
TXK TXK tyrosine kinase
ZNF155 zinc finger protein 155

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AGMAT agmatine ureohydrolase (agmatinase)
AMT aminomethyltransferase
ANP32A-IT1 ANP32A intronic transcript 1
ARL14 ADP-ribosylation factor-like 14
BAX BCL2-associated X protein
BICC1 BicC family RNA binding protein 1
CAMKMT calmodulin-lysine N-methyltransferase
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CD82 CD82 molecule
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLCA1 chloride channel accessory 1
CLCN5 chloride channel, voltage-sensitive 5
CLDN1 claudin 1
CLIC3 chloride intracellular channel 3
CNTNAP3B contactin associated protein-like 3B
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRMP1 collapsin response mediator protein 1
CSRNP3 cysteine-serine-rich nuclear protein 3
CXCL2 chemokine (C-X-C motif) ligand 2
CYB5R2 cytochrome b5 reductase 2
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DLK2 delta-like 2 homolog (Drosophila)
FAM134B family with sequence similarity 134, member B
FBXO31 F-box protein 31
FLJ21369 uncharacterized protein FLJ21369
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GEMIN8 gem (nuclear organelle) associated protein 8
GRAMD1B GRAM domain containing 1B
GRTP1 growth hormone regulated TBC protein 1
GRWD1 glutamate-rich WD repeat containing 1
GUSBP3 glucuronidase, beta pseudogene 3
H2AFJ H2A histone family, member J
HDAC7 histone deacetylase 7
HIRA histone cell cycle regulator
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXA4 homeobox A4
HOXC4 homeobox C4
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IFI6 interferon, alpha-inducible protein 6
JAM3 junctional adhesion molecule 3
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA0754 KIAA0754
KIFC1 kinesin family member C1
KLF3 Kruppel-like factor 3 (basic)
KRT31 keratin 31, type I
LMO2 LIM domain only 2 (rhombotin-like 1)
LRRK1 leucine-rich repeat kinase 1
MAPK12 mitogen-activated protein kinase 12
MTSS1L metastasis suppressor 1-like
MUC3A mucin 3A, cell surface associated
MYLIP myosin regulatory light chain interacting protein
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NGF nerve growth factor (beta polypeptide)
NOD1 nucleotide-binding oligomerization domain containing 1
NPVF neuropeptide VF precursor
NT5DC3 5'-nucleotidase domain containing 3
OCEL1 occludin/ELL domain containing 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PBOV1 prostate and breast cancer overexpressed 1
PMCH pro-melanin-concentrating hormone
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRPH peripherin
QSER1 glutamine and serine rich 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RUSC2 RUN and SH3 domain containing 2
SCML2 sex comb on midleg-like 2 (Drosophila)
SH2D2A SH2 domain containing 2A
SLC12A9 solute carrier family 12, member 9
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLN sarcolipin
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPEG SPEG complex locus
SREBF2 sterol regulatory element binding transcription factor 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TCEAL2 transcription elongation factor A (SII)-like 2
THRB thyroid hormone receptor, beta
THSD4 thrombospondin, type I, domain containing 4
TM6SF1 transmembrane 6 superfamily member 1
TMEM212 transmembrane protein 212
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TRPM4 transient receptor potential cation channel, subfamily M, member 4
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
VWA1 von Willebrand factor A domain containing 1
WDR62 WD repeat domain 62
ZBTB6 zinc finger and BTB domain containing 6
ZC3H12A zinc finger CCCH-type containing 12A
ZNF428 zinc finger protein 428
ZNF528 zinc finger protein 528
ZNF574 zinc finger protein 574
ZNF76 zinc finger protein 76