death Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism. (Gene Ontology, GO_0016265)
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Genes

352 proteins co-occuring with the biological term death in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACACA acetyl-CoA carboxylase alpha
ACIN1 apoptotic chromatin condensation inducer 1
ACLY ATP citrate lyase
ADD1 adducin 1 (alpha)
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALK anaplastic lymphoma receptor tyrosine kinase
ANXA1 annexin A1
ANXA2 annexin A2
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APP amyloid beta (A4) precursor protein
APTX aprataxin
AQP9 aquaporin 9
AR androgen receptor
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARFIP2 ADP-ribosylation factor interacting protein 2
ASIC1 acid sensing (proton gated) ion channel 1
ATF2 activating transcription factor 2
ATF4 activating transcription factor 4
ATM ATM serine/threonine kinase
ATN1 atrophin 1
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATXN1 ataxin 1
BAD BCL2-associated agonist of cell death
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCR breakpoint cluster region
BECN1 beclin 1, autophagy related
BID BH3 interacting domain death agonist
BIK BCL2-interacting killer (apoptosis-inducing)
BIRC5 baculoviral IAP repeat containing 5
BRCA1 breast cancer 1, early onset
BTG2 BTG family, member 2
BUB3 BUB3 mitotic checkpoint protein
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CARD11 caspase recruitment domain family, member 11
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCND1 cyclin D1
CD37 CD37 molecule
CDC25A cell division cycle 25A
CDC25C cell division cycle 25C
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK5 cyclin-dependent kinase 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CENPA centromere protein A
CFL1 cofilin 1 (non-muscle)
CFLAR CASP8 and FADD-like apoptosis regulator
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHUK conserved helix-loop-helix ubiquitous kinase
CLK2 CDC-like kinase 2
COX2
CREB1 cAMP responsive element binding protein 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRYAA crystallin, alpha A
CRYAB crystallin, alpha B
CSF1R colony stimulating factor 1 receptor
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CTBP1 C-terminal binding protein 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYCS cytochrome c, somatic
DAPK1 death-associated protein kinase 1
DAPK2 death-associated protein kinase 2
DAPK3 death-associated protein kinase 3
DAXX death-domain associated protein
DCTN1 dynactin 1
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DNM1L dynamin 1-like
DPYSL2 dihydropyrimidinase-like 2
DSP desmoplakin
DUSP1 dual specificity phosphatase 1
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
E2F1 E2F transcription factor 1
E2F4 E2F transcription factor 4, p107/p130-binding
EEF2K eukaryotic elongation factor 2 kinase
EGFR epidermal growth factor receptor
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELK1 ELK1, member of ETS oncogene family
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
ESR1 estrogen receptor 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FADD Fas (TNFRSF6)-associated via death domain
FAF1 Fas (TNFRSF6) associated factor 1
FANCE Fanconi anemia, complementation group E
FAS Fas cell surface death receptor
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FEN1 flap structure-specific endonuclease 1
FLT3 fms-related tyrosine kinase 3
FOXG1 forkhead box G1
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXO4 forkhead box O4
FOXO6 forkhead box O6
FRK fyn-related Src family tyrosine kinase
FUS FUS RNA binding protein
FYN FYN proto-oncogene, Src family tyrosine kinase
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAP43 growth associated protein 43
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA4 GATA binding protein 4
GJA1 gap junction protein, alpha 1, 43kDa
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GOLGA3 golgin A3
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GYS1 glycogen synthase 1 (muscle)
H2AFX H2A histone family, member X
H3F3B H3 histone, family 3B (H3.3B)
HAVCR2 hepatitis A virus cellular receptor 2
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HIST1H2BB histone cluster 1, H2bb
HIST1H2BN histone cluster 1, H2bn
HIST1H3A histone cluster 1, H3a
HMGB1 high mobility group box 1
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPB1 heat shock 27kDa protein 1
HSPB6 heat shock protein, alpha-crystallin-related, B6
HTRA2 HtrA serine peptidase 2
HTT huntingtin
IER3 immediate early response 3
IGFBP3 insulin-like growth factor binding protein 3
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL4R interleukin 4 receptor
IL6ST interleukin 6 signal transducer
IL7R interleukin 7 receptor
IP6K2 inositol hexakisphosphate kinase 2
IRAK1 interleukin-1 receptor-associated kinase 1
IRS1 insulin receptor substrate 1
JAK2 Janus kinase 2
JUN jun proto-oncogene
KAT5 K(lysine) acetyltransferase 5
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KIF11 kinesin family member 11
KRT8 keratin 8, type II
LASP1 LIM and SH3 protein 1
LAT linker for activation of T cells
LATS2 large tumor suppressor kinase 2
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LGALS3 lectin, galactoside-binding, soluble, 3
LIMK1 LIM domain kinase 1
LIMK2 LIM domain kinase 2
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP2 microtubule-associated protein 2
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPT microtubule-associated protein tau
MARK1 MAP/microtubule affinity-regulating kinase 1
MARK2 MAP/microtubule affinity-regulating kinase 2
MCL1 myeloid cell leukemia 1
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MCU mitochondrial calcium uniporter
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MEF2D myocyte enhancer factor 2D
MET MET proto-oncogene, receptor tyrosine kinase
MFN2 mitofusin 2
MITF microphthalmia-associated transcription factor
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYBPC3 myosin binding protein C, cardiac
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
MYL12B myosin, light chain 12B, regulatory
NBN nibrin
NCL nucleolin
NDC80 NDC80 kinetochore complex component
NFE2L1 nuclear factor, erythroid 2-like 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NGFR nerve growth factor receptor
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOS3 nitric oxide synthase 3 (endothelial cell)
NR1I3 nuclear receptor subfamily 1, group I, member 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
PA2G4 proliferation-associated 2G4, 38kDa
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PARK2 parkin RBR E3 ubiquitin protein ligase
PARP1 poly (ADP-ribose) polymerase 1
PARP10 poly (ADP-ribose) polymerase family, member 10
PDCD10 programmed cell death 10
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDCD5 programmed cell death 5
PDPK1 3-phosphoinositide dependent protein kinase 1
PEA15 phosphoprotein enriched in astrocytes 15
PGRMC1 progesterone receptor membrane component 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIDD1 p53-induced death domain protein 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PKM pyruvate kinase, muscle
PKN1 protein kinase N1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCG1 phospholipase C, gamma 1
PLN phospholamban
PML promyelocytic leukemia
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PRDX2 peroxiredoxin 2
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCG protein kinase C, gamma
PRKCI protein kinase C, iota
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PSEN1 presenilin 1
PSEN2 presenilin 2
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN3 protein tyrosine phosphatase, non-receptor type 3
PTRH2 peptidyl-tRNA hydrolase 2
PXN paxillin
RAD51 RAD51 recombinase
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RB1 retinoblastoma 1
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RET ret proto-oncogene
RHO rhodopsin
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RPS3 ribosomal protein S3
RPS6 ribosomal protein S6
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RYR2 ryanodine receptor 2 (cardiac)
SATB1 SATB homeobox 1
SAV1 salvador family WW domain containing protein 1
SCN5A sodium channel, voltage gated, type V alpha subunit
SET SET nuclear proto-oncogene
SFN stratifin
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SH3GLB1 SH3-domain GRB2-like endophilin B1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIAH1 siah E3 ubiquitin protein ligase 1
SIRT1 sirtuin 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMC1A structural maintenance of chromosomes 1A
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNAP91 synaptosomal-associated protein, 91kDa
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNW1 SNW domain containing 1
SPHK1 sphingosine kinase 1
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRPK2 SRSF protein kinase 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK3 serine/threonine kinase 3
STK38 serine/threonine kinase 38
STK4 serine/threonine kinase 4
STMN1 stathmin 1
STYK1 serine/threonine/tyrosine kinase 1
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae)
SYN1 synapsin I
TACC3 transforming, acidic coiled-coil containing protein 3
TARDBP TAR DNA binding protein
TCF3 transcription factor 3
THEM4 thioesterase superfamily member 4
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
TPT1 tumor protein, translationally-controlled 1
TRADD TNFRSF1A-associated via death domain
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TSC2 tuberous sclerosis 2
UHRF1 ubiquitin-like with PHD and ring finger domains 1
URI1 URI1, prefoldin-like chaperone
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VASP vasodilator-stimulated phosphoprotein
VDAC1 voltage-dependent anion channel 1
VRK1 vaccinia related kinase 1
WEE1 WEE1 G2 checkpoint kinase
WWOX WW domain containing oxidoreductase
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YAP1 Yes-associated protein 1
YES1 YES proto-oncogene 1, Src family tyrosine kinase
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
YY1 YY1 transcription factor
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa