dcm Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description An intrinsic cardiomyopathy that results in damage to the myocardium causing the heart to pump blood inefficiently.|A form of CARDIAC MUSCLE disease that is characterized by ventricular dilation, VENTRICULAR DYSFUNCTION, and HEART FAILURE. Risk factors include SMOKING; ALCOHOL DRINKING; HYPERTENSION; INFECTION; PREGNANCY; and mutations in the LMNA gene encoding LAMIN TYPE A, a NUCLEAR LAMINA protein.|decreased function of the heart associated with cardiac enlargement and congestive heart failure (Experimental Factor Ontology, EFO_0000407)
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Genes

41 genes co-occuring with the biological term dcm in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ADORA2A adenosine A2a receptor
ADRB1 adrenoceptor beta 1
ALMS1 Alstrom syndrome protein 1
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
AR androgen receptor
BAG3 BCL2-associated athanogene 3
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
DOLK dolichol kinase
EGFR epidermal growth factor receptor
ESR1 estrogen receptor 1
FHOD3 formin homology 2 domain containing 3
GADD45A growth arrest and DNA-damage-inducible, alpha
GATA4 GATA binding protein 4
GSTT1 glutathione S-transferase theta 1
HLA-C major histocompatibility complex, class I, C
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HRC histidine rich calcium binding protein
HSPA1B heat shock 70kDa protein 1B
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular)
IL17A interleukin 17A
IL17F interleukin 17F
IL1RN interleukin 1 receptor antagonist
IL23R interleukin 23 receptor
LMNA lamin A/C
LTA lymphotoxin alpha
MYOZ1 myozenin 1
MYOZ2 myozenin 2
OSM oncostatin M
PDLIM3 PDZ and LIM domain 3
PEPD peptidase D
RTN4 reticulon 4
SCN5A sodium channel, voltage gated, type V alpha subunit
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC25A5P8 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 pseudogene 8
TAZ tafazzin
TLR4 toll-like receptor 4
TNNI3 troponin I type 3 (cardiac)
TNNT2 troponin T type 2 (cardiac)
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TTN titin