daunorubicin-7525 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the daunorubicin-7525 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
AHNAK2 AHNAK nucleoprotein 2
AK1 adenylate kinase 1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
APC adenomatous polyposis coli
AQP3 aquaporin 3 (Gill blood group)
ARC activity-regulated cytoskeleton-associated protein
ARHGAP1 Rho GTPase activating protein 1
ATF3 activating transcription factor 3
BTG2 BTG family, member 2
C11ORF95 chromosome 11 open reading frame 95
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAPRIN2 caprin family member 2
CD83 CD83 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEL carboxyl ester lipase
CHKB choline kinase beta
CLCN2 chloride channel, voltage-sensitive 2
CST6 cystatin E/M
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYLD cylindromatosis (turban tumor syndrome)
DFNB31 deafness, autosomal recessive 31
EN2 engrailed homeobox 2
EPHA2 EPH receptor A2
EPHB3 EPH receptor B3
ERO1LB ERO1-like beta (S. cerevisiae)
FAM212B family with sequence similarity 212, member B
FAS Fas cell surface death receptor
FLJ42627 uncharacterized LOC645644
FOSL1 FOS-like antigen 1
FSCN1 fascin actin-bundling protein 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GLS glutaminase
GLS2 glutaminase 2 (liver, mitochondrial)
GPATCH2L G patch domain containing 2-like
GPR87 G protein-coupled receptor 87
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C
HCLS1 hematopoietic cell-specific Lyn substrate 1
HIC2 hypermethylated in cancer 2
HLA-G major histocompatibility complex, class I, G
HMHA1 histocompatibility (minor) HA-1
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
IFT27 intraflagellar transport 27
INPP1 inositol polyphosphate-1-phosphatase
JAG1 jagged 1
KAT2B K(lysine) acetyltransferase 2B
LIF leukemia inhibitory factor
LIMK2 LIM domain kinase 2
LOC157562 uncharacterized LOC157562
LOC730101 uncharacterized LOC730101
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP2K3 mitogen-activated protein kinase kinase 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MSX1 msh homeobox 1
MXD4 MAX dimerization protein 4
MYO1F myosin IF
NHLH2 nescient helix loop helix 2
NLRX1 NLR family member X1
NPTX1 neuronal pentraxin I
NUPR1 nuclear protein, transcriptional regulator, 1
OAZ3 ornithine decarboxylase antizyme 3
OSGIN1 oxidative stress induced growth inhibitor 1
PDE4A phosphodiesterase 4A, cAMP-specific
PDE4C phosphodiesterase 4C, cAMP-specific
PGF placental growth factor
PIDD1 p53-induced death domain protein 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLK3 polo-like kinase 3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
RAB40B RAB40B, member RAS oncogene family
RALGDS ral guanine nucleotide dissociation stimulator
RNF19B ring finger protein 19B
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SESN1 sestrin 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SOCS1 suppressor of cytokine signaling 1
SOX9 SRY (sex determining region Y)-box 9
ST20 suppressor of tumorigenicity 20
SYNM synemin, intermediate filament protein
SYT17 synaptotagmin XVII
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
THBD thrombomodulin
TMEM144 transmembrane protein 144
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TP53I3 tumor protein p53 inducible protein 3
TPST2 tyrosylprotein sulfotransferase 2
TRIM3 tripartite motif containing 3
ZDHHC11 zinc finger, DHHC-type containing 11
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF665 zinc finger protein 665
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAP2 ArfGAP with dual PH domains 2
AMIGO2 adhesion molecule with Ig-like domain 2
ARHGAP11A Rho GTPase activating protein 11A
ASTE1 asteroid homolog 1 (Drosophila)
BOLA1 bolA family member 1
BORA bora, aurora kinase A activator
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C1QTNF3 C1q and tumor necrosis factor related protein 3
CBR3 carbonyl reductase 3
CENPE centromere protein E, 312kDa
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CUTC cutC copper transporter
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding)
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DPY19L1P1 DPY19L1 pseudogene 1
DTWD1 DTW domain containing 1
E2F8 E2F transcription factor 8
EFNA3 ephrin-A3
ERCC6L excision repair cross-complementation group 6-like
FADS2 fatty acid desaturase 2
FAM110B family with sequence similarity 110, member B
FGD1 FYVE, RhoGEF and PH domain containing 1
FPGT fucose-1-phosphate guanylyltransferase
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GLTSCR1L GLTSCR1-like
GTF2IRD1 GTF2I repeat domain containing 1
GTPBP2 GTP binding protein 2
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H4A histone cluster 1, H4a
HIST1H4C histone cluster 1, H4c
HJURP Holliday junction recognition protein
HOXC10 homeobox C10
IFT140 intraflagellar transport 140
IFT81 intraflagellar transport 81
JADE1 jade family PHD finger 1
KIF14 kinesin family member 14
KIF16B kinesin family member 16B
LMNB1 lamin B1
LRRC49 leucine rich repeat containing 49
MBD5 methyl-CpG binding domain protein 5
MCMBP minichromosome maintenance complex binding protein
MEIS1 Meis homeobox 1
MIS18BP1 MIS18 binding protein 1
MISP mitotic spindle positioning
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit
NAV2 neuron navigator 2
NCAPH non-SMC condensin I complex, subunit H
NDC80 NDC80 kinetochore complex component
NNAT neuronatin
NOD1 nucleotide-binding oligomerization domain containing 1
NPY1R neuropeptide Y receptor Y1
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PARD6A par-6 family cell polarity regulator alpha
PER3 period circadian clock 3
PFAS phosphoribosylformylglycinamidine synthase
PIBF1 progesterone immunomodulatory binding factor 1
PRIM1 primase, DNA, polypeptide 1 (49kDa)
PSRC1 proline/serine-rich coiled-coil 1
RAP1GAP2 RAP1 GTPase activating protein 2
RIBC2 RIB43A domain with coiled-coils 2
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
RPL13P5 ribosomal protein L13 pseudogene 5
RPP40 ribonuclease P/MRP 40kDa subunit
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SCAI suppressor of cancer cell invasion
SH2D4A SH2 domain containing 4A
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SOCS2 suppressor of cytokine signaling 2
SPC25 SPC25, NDC80 kinetochore complex component
SPTBN2 spectrin, beta, non-erythrocytic 2
STIL SCL/TAL1 interrupting locus
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
THRAP3 thyroid hormone receptor associated protein 3
TIPIN TIMELESS interacting protein
TMC5 transmembrane channel-like 5
TWF2 twinfilin actin binding protein 2
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
WDR25 WD repeat domain 25
WDR62 WD repeat domain 62
WRN Werner syndrome, RecQ helicase-like
ZBTB22 zinc finger and BTB domain containing 22
ZBTB3 zinc finger and BTB domain containing 3
ZBTB6 zinc finger and BTB domain containing 6
ZMYM1 zinc finger, MYM-type 1
ZNF165 zinc finger protein 165
ZNF184 zinc finger protein 184
ZNF205 zinc finger protein 205
ZNF33B zinc finger protein 33B
ZNF692 zinc finger protein 692
ZNHIT2 zinc finger, HIT-type containing 2