daunorubicin-7511 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the daunorubicin-7511 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
AKR1C2 aldo-keto reductase family 1, member C2
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
APOE apolipoprotein E
ARID5A AT rich interactive domain 5A (MRF1-like)
ARPIN actin-related protein 2/3 complex inhibitor
ATF5 activating transcription factor 5
ATP10A ATPase, class V, type 10A
BDNF brain-derived neurotrophic factor
BTBD18 BTB (POZ) domain containing 18
C22ORF29 chromosome 22 open reading frame 29
C8A complement component 8, alpha polypeptide
CCNO cyclin O
CDIP1 cell death-inducing p53 target 1
CDK12 cyclin-dependent kinase 12
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CNPY4 canopy FGF signaling regulator 4
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CROCC ciliary rootlet coiled-coil, rootletin
CRY2 cryptochrome circadian clock 2
CXCL2 chemokine (C-X-C motif) ligand 2
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DEPTOR DEP domain containing MTOR-interacting protein
DHFR dihydrofolate reductase
DMWD dystrophia myotonica, WD repeat containing
DUSP10 dual specificity phosphatase 10
EDIL3 EGF-like repeats and discoidin I-like domains 3
ELOVL5 ELOVL fatty acid elongase 5
EPHA4 EPH receptor A4
FAM120C family with sequence similarity 120C
FAM46A family with sequence similarity 46, member A
FER1L4 fer-1-like family member 4, pseudogene (functional)
FLCN folliculin
GLS glutaminase
GPATCH3 G patch domain containing 3
GPR1 G protein-coupled receptor 1
HIST1H1T histone cluster 1, H1t
HIST1H2BG histone cluster 1, H2bg
HRG histidine-rich glycoprotein
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
ICAM1 intercellular adhesion molecule 1
ITPKC inositol-trisphosphate 3-kinase C
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KLHL29 kelch-like family member 29
KRIT1 KRIT1, ankyrin repeat containing
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LTB4R leukotriene B4 receptor
MECP2 methyl CpG binding protein 2
MICB MHC class I polypeptide-related sequence B
N4BP2L2 NEDD4 binding protein 2-like 2
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NOTCH3 notch 3
NPIPB15 nuclear pore complex interacting protein family, member B15
NXF1 nuclear RNA export factor 1
OAZ3 ornithine decarboxylase antizyme 3
OLFML2A olfactomedin-like 2A
PAIP2B poly(A) binding protein interacting protein 2B
PCM1 pericentriolar material 1
PEG3 paternally expressed 3
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRDM2 PR domain containing 2, with ZNF domain
PRF1 perforin 1 (pore forming protein)
PRRC2B proline-rich coiled-coil 2B
RAB36 RAB36, member RAS oncogene family
RGS12 regulator of G-protein signaling 12
RSU1 Ras suppressor protein 1
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SMG7 SMG7 nonsense mediated mRNA decay factor
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNHG3 small nucleolar RNA host gene 3
SPN sialophorin
SQSTM1 sequestosome 1
STAG3 stromal antigen 3
TEAD3 TEA domain family member 3
TEX14 testis expressed 14
TFEB transcription factor EB
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TOP3B topoisomerase (DNA) III beta
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TUBA3C tubulin, alpha 3c
UBXN1 UBX domain protein 1
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDR62 WD repeat domain 62
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WSB1 WD repeat and SOCS box containing 1
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF205 zinc finger protein 205
ZNF446 zinc finger protein 446
ZNF821 zinc finger protein 821
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
AMIGO2 adhesion molecule with Ig-like domain 2
ANAPC10 anaphase promoting complex subunit 10
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
ARHGAP12 Rho GTPase activating protein 12
ARSJ arylsulfatase family, member J
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
BCAR3 breast cancer anti-estrogen resistance 3
BLM Bloom syndrome, RecQ helicase-like
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CENPE centromere protein E, 312kDa
CEP192 centrosomal protein 192kDa
CLDN4 claudin 4
CLIP4 CAP-GLY domain containing linker protein family, member 4
COMMD8 COMM domain containing 8
DCK deoxycytidine kinase
DCTN4 dynactin 4 (p62)
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DENND1B DENN/MADD domain containing 1B
DEPDC1 DEP domain containing 1
DMXL1 Dmx-like 1
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
ERBB2IP erbb2 interacting protein
EXOC2 exocyst complex component 2
EXOC5 exocyst complex component 5
FAM169A family with sequence similarity 169, member A
FAM188A family with sequence similarity 188, member A
FEM1C fem-1 homolog c (C. elegans)
FPGT fucose-1-phosphate guanylyltransferase
GLI3 GLI family zinc finger 3
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GRAMD3 GRAM domain containing 3
H1F0 H1 histone family, member 0
HARS2 histidyl-tRNA synthetase 2, mitochondrial
HAS2 hyaluronan synthase 2
HIST1H1E histone cluster 1, H1e
HMGA2 high mobility group AT-hook 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IL18 interleukin 18
INHBB inhibin, beta B
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KIF14 kinesin family member 14
KIF23 kinesin family member 23
KLF11 Kruppel-like factor 11
LHFPL2 lipoma HMGIC fusion partner-like 2
LHX6 LIM homeobox 6
LMNB1 lamin B1
LYRM2 LYR motif containing 2
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MCRS1 microspherule protein 1
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
MSL1 male-specific lethal 1 homolog (Drosophila)
MTG1 mitochondrial ribosome-associated GTPase 1
NAP1L3 nucleosome assembly protein 1-like 3
NDRG4 NDRG family member 4
NEK4 NIMA-related kinase 4
NFE2L3 nuclear factor, erythroid 2-like 3
NHLRC2 NHL repeat containing 2
NMD3 NMD3 ribosome export adaptor
NR3C2 nuclear receptor subfamily 3, group C, member 2
NTSR1 neurotensin receptor 1 (high affinity)
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
P3H2 prolyl 3-hydroxylase 2
PALMD palmdelphin
PDZD2 PDZ domain containing 2
PEX2 peroxisomal biogenesis factor 2
PHC2 polyhomeotic homolog 2 (Drosophila)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIBF1 progesterone immunomodulatory binding factor 1
PLK1 polo-like kinase 1
PODXL podocalyxin-like
POGK pogo transposable element with KRAB domain
POT1 protection of telomeres 1
PPAP2B phosphatidic acid phosphatase type 2B
PPARG peroxisome proliferator-activated receptor gamma
PSRC1 proline/serine-rich coiled-coil 1
RAI14 retinoic acid induced 14
RAP1GAP2 RAP1 GTPase activating protein 2
RHOT1 ras homolog family member T1
RIN2 Ras and Rab interactor 2
SGMS1 sphingomyelin synthase 1
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SPIN1 spindlin 1
SPRY2 sprouty homolog 2 (Drosophila)
SREK1 splicing regulatory glutamine/lysine-rich protein 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM121 transmembrane protein 121
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRAF5 TNF receptor-associated factor 5
TRIM9 tripartite motif containing 9
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TSPAN1 tetraspanin 1
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
ZNF365 zinc finger protein 365
ZNF692 zinc finger protein 692