daunorubicin-7507 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the daunorubicin-7507 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
AGBL5 ATP/GTP binding protein-like 5
AHNAK2 AHNAK nucleoprotein 2
AK1 adenylate kinase 1
ALS2CL ALS2 C-terminal like
APLP1 amyloid beta (A4) precursor-like protein 1
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ARC activity-regulated cytoskeleton-associated protein
ATF3 activating transcription factor 3
ATP13A2 ATPase type 13A2
BACE1 beta-site APP-cleaving enzyme 1
BBS7 Bardet-Biedl syndrome 7
BMP1 bone morphogenetic protein 1
BTG2 BTG family, member 2
CD82 CD82 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DFNB31 deafness, autosomal recessive 31
DMPK dystrophia myotonica-protein kinase
DPYSL4 dihydropyrimidinase-like 4
EPHA2 EPH receptor A2
EPHB3 EPH receptor B3
F8 coagulation factor VIII, procoagulant component
FAS Fas cell surface death receptor
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45G growth arrest and DNA-damage-inducible, gamma
GAS6 growth arrest-specific 6
GLRX3 glutaredoxin 3
GLS glutaminase
GLS2 glutaminase 2 (liver, mitochondrial)
GPR87 G protein-coupled receptor 87
HBEGF heparin-binding EGF-like growth factor
HIC2 hypermethylated in cancer 2
HLA-E major histocompatibility complex, class I, E
HMOX1 heme oxygenase 1
HPS1 Hermansky-Pudlak syndrome 1
HPX hemopexin
IFT27 intraflagellar transport 27
IL17RB interleukin 17 receptor B
INPP1 inositol polyphosphate-1-phosphatase
JAG1 jagged 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
LIF leukemia inhibitory factor
LIMK2 LIM domain kinase 2
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MIR22HG MIR22 host gene
MSX1 msh homeobox 1
MXD4 MAX dimerization protein 4
NHLH2 nescient helix loop helix 2
NPTX1 neuronal pentraxin I
NYNRIN NYN domain and retroviral integrase containing
OLFML2A olfactomedin-like 2A
PAIP2B poly(A) binding protein interacting protein 2B
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE4A phosphodiesterase 4A, cAMP-specific
PDGFA platelet-derived growth factor alpha polypeptide
PGF placental growth factor
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
RALGDS ral guanine nucleotide dissociation stimulator
RNF19B ring finger protein 19B
RPL35A ribosomal protein L35a
SESN1 sestrin 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLIT2 slit homolog 2 (Drosophila)
SOCS1 suppressor of cytokine signaling 1
SOD2 superoxide dismutase 2, mitochondrial
SOX9 SRY (sex determining region Y)-box 9
SSTR4 somatostatin receptor 4
STAT5B signal transducer and activator of transcription 5B
SUSD6 sushi domain containing 6
SYNM synemin, intermediate filament protein
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TEX14 testis expressed 14
TLR5 toll-like receptor 5
TMEM144 transmembrane protein 144
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM231 transmembrane protein 231
TMEM63A transmembrane protein 63A
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TP53I3 tumor protein p53 inducible protein 3
TREX1 three prime repair exonuclease 1
TRIM3 tripartite motif containing 3
UBE3A ubiquitin protein ligase E3A
UBXN1 UBX domain protein 1
USB1 U6 snRNA biogenesis 1
WAS Wiskott-Aldrich syndrome
ZNF174 zinc finger protein 174
ZNF324 zinc finger protein 324
ZNF34 zinc finger protein 34
ZNF654 zinc finger protein 654
ZNF79 zinc finger protein 79
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
ACKR3 atypical chemokine receptor 3
AMIGO2 adhesion molecule with Ig-like domain 2
ASB13 ankyrin repeat and SOCS box containing 13
ASPHD1 aspartate beta-hydroxylase domain containing 1
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ASUN asunder spermatogenesis regulator
ATP11B ATPase, class VI, type 11B
BAK1 BCL2-antagonist/killer 1
BCAR3 breast cancer anti-estrogen resistance 3
BCL9 B-cell CLL/lymphoma 9
BLM Bloom syndrome, RecQ helicase-like
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C11ORF71 chromosome 11 open reading frame 71
C12ORF43 chromosome 12 open reading frame 43
C14ORF132 chromosome 14 open reading frame 132
CAMK1 calcium/calmodulin-dependent protein kinase I
CBR3 carbonyl reductase 3
CDK20 cyclin-dependent kinase 20
CDK3 cyclin-dependent kinase 3
CENPE centromere protein E, 312kDa
CEP192 centrosomal protein 192kDa
CHST10 carbohydrate sulfotransferase 10
CNGB3 cyclic nucleotide gated channel beta 3
COMMD8 COMM domain containing 8
CUTC cutC copper transporter
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DOCK1 dedicator of cytokinesis 1
E2F8 E2F transcription factor 8
EML4 echinoderm microtubule associated protein like 4
EXOC2 exocyst complex component 2
EXOSC9 exosome component 9
FAM86C1 family with sequence similarity 86, member C1
FBXO31 F-box protein 31
FKBP14 FK506 binding protein 14, 22 kDa
FZD4 frizzled class receptor 4
GBP2 guanylate binding protein 2, interferon-inducible
GPR19 G protein-coupled receptor 19
HIST1H1C histone cluster 1, H1c
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
JMJD1C jumonji domain containing 1C
KIAA0125 KIAA0125
KIF13B kinesin family member 13B
KIF14 kinesin family member 14
KIF16B kinesin family member 16B
KIZ kizuna centrosomal protein
LENEP lens epithelial protein
LMBR1L limb development membrane protein 1-like
MAP9 microtubule-associated protein 9
MCM10 minichromosome maintenance complex component 10
MED7 mediator complex subunit 7
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MNS1 meiosis-specific nuclear structural 1
MPI mannose phosphate isomerase
MTMR6 myotubularin related protein 6
MUM1 melanoma associated antigen (mutated) 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAV2 neuron navigator 2
NDC80 NDC80 kinetochore complex component
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NLK nemo-like kinase
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae)
NPY1R neuropeptide Y receptor Y1
OPN3 opsin 3
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PCDHB3 protocadherin beta 3
PFAS phosphoribosylformylglycinamidine synthase
PLK1 polo-like kinase 1
POLI polymerase (DNA directed) iota
PSKH1 protein serine kinase H1
RAP1GAP2 RAP1 GTPase activating protein 2
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RPL13P5 ribosomal protein L13 pseudogene 5
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RUFY2 RUN and FYVE domain containing 2
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5)
THNSL1 threonine synthase-like 1 (S. cerevisiae)
THYN1 thymocyte nuclear protein 1
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TIPIN TIMELESS interacting protein
TRAF5 TNF receptor-associated factor 5
TTC17 tetratricopeptide repeat domain 17
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
WDR7 WD repeat domain 7
YEATS4 YEATS domain containing 4
ZBTB3 zinc finger and BTB domain containing 3
ZNF107 zinc finger protein 107
ZNF165 zinc finger protein 165
ZNF184 zinc finger protein 184
ZNF271P zinc finger protein 271, pseudogene
ZNF692 zinc finger protein 692