daunorubicin-4983 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the daunorubicin-4983 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACSL5 acyl-CoA synthetase long-chain family member 5
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAM15 ADAM metallopeptidase domain 15
ADAM19 ADAM metallopeptidase domain 19
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALOX15B arachidonate 15-lipoxygenase, type B
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCAM basal cell adhesion molecule (Lutheran blood group)
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BGLAP bone gamma-carboxyglutamate (gla) protein
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C20ORF27 chromosome 20 open reading frame 27
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CASP5 caspase 5, apoptosis-related cysteine peptidase
CD6 CD6 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CDHR2 cadherin-related family member 2
CRISP2 cysteine-rich secretory protein 2
CTSZ cathepsin Z
DCBLD2 discoidin, CUB and LCCL domain containing 2
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DSPP dentin sialophosphoprotein
EGFL7 EGF-like-domain, multiple 7
EPHB6 EPH receptor B6
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FGF22 fibroblast growth factor 22
FKBP8 FK506 binding protein 8, 38kDa
FSCN1 fascin actin-bundling protein 1
FSCN3 fascin actin-bundling protein 3, testicular
GAMT guanidinoacetate N-methyltransferase
GCHFR GTP cyclohydrolase I feedback regulator
GM2A GM2 ganglioside activator
GPC3 glypican 3
GRPR gastrin-releasing peptide receptor
GSPT1 G1 to S phase transition 1
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HIST1H1T histone cluster 1, H1t
HIST1H3B histone cluster 1, H3b
HOMER3 homer scaffolding protein 3
HOXB2 homeobox B2
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KIF1C kinesin family member 1C
KRT20 keratin 20, type I
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MEG3 maternally expressed 3 (non-protein coding)
MMP3 matrix metallopeptidase 3
MOB3B MOB kinase activator 3B
MTSS1L metastasis suppressor 1-like
NDRG2 NDRG family member 2
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPM3 nucleophosmin/nucleoplasmin 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
PARVB parvin, beta
PAX2 paired box 2
PDLIM5 PDZ and LIM domain 5
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLAT plasminogen activator, tissue
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RFTN1 raftlin, lipid raft linker 1
RPL29 ribosomal protein L29
RPS2 ribosomal protein S2
S100A11 S100 calcium binding protein A11
S100A9 S100 calcium binding protein A9
SASH3 SAM and SH3 domain containing 3
SCN1B sodium channel, voltage gated, type I beta subunit
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SNTA1 syntrophin, alpha 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SPON1 spondin 1, extracellular matrix protein
SSX1 synovial sarcoma, X breakpoint 1
STS steroid sulfatase (microsomal), isozyme S
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYT13 synaptotagmin XIII
TAT tyrosine aminotransferase
TBXA2R thromboxane A2 receptor
TCTN2 tectonic family member 2
TFDP3 transcription factor Dp family, member 3
TIMP3 TIMP metallopeptidase inhibitor 3
TMPRSS15 transmembrane protease, serine 15
TP53I11 tumor protein p53 inducible protein 11
TP63 tumor protein p63
TPMT thiopurine S-methyltransferase
TRIM10 tripartite motif containing 10
UNC93B1 unc-93 homolog B1 (C. elegans)
VARS valyl-tRNA synthetase
VSNL1 visinin-like 1
VWA5A von Willebrand factor A domain containing 5A
ZNF407 zinc finger protein 407
ZNF44 zinc finger protein 44
ZYX zyxin

decreased expression

Symbol Name
AEN apoptosis enhancing nuclease
AMIGO2 adhesion molecule with Ig-like domain 2
ANKRD49 ankyrin repeat domain 49
ARID5B AT rich interactive domain 5B (MRF1-like)
ARL4A ADP-ribosylation factor-like 4A
ASTE1 asteroid homolog 1 (Drosophila)
BANP BTG3 associated nuclear protein
BCL10 B-cell CLL/lymphoma 10
CDCA4 cell division cycle associated 4
CDR2 cerebellar degeneration-related protein 2, 62kDa
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CENPC centromere protein C
DDIT4 DNA-damage-inducible transcript 4
DNAAF2 dynein, axonemal, assembly factor 2
E2F6 E2F transcription factor 6
EFNA1 ephrin-A1
EFNA4 ephrin-A4
EGR3 early growth response 3
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
EPPK1 epiplakin 1
FADD Fas (TNFRSF6)-associated via death domain
FBXO5 F-box protein 5
FOXA1 forkhead box A1
FOXC1 forkhead box C1
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
HAUS3 HAUS augmin-like complex, subunit 3
HIST1H4C histone cluster 1, H4c
HOXA5 homeobox A5
HOXC6 homeobox C6
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IER2 immediate early response 2
IER3 immediate early response 3
IER5 immediate early response 5
IRX5 iroquois homeobox 5
JMJD1C jumonji domain containing 1C
KANSL2 KAT8 regulatory NSL complex subunit 2
KIAA0232 KIAA0232
KLF10 Kruppel-like factor 10
LEMD3 LEM domain containing 3
MAD2L1BP MAD2L1 binding protein
METTL18 methyltransferase like 18
MFSD5 major facilitator superfamily domain containing 5
MIR22HG MIR22 host gene
MORC3 MORC family CW-type zinc finger 3
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
MSL2 male-specific lethal 2 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NUP153 nucleoporin 153kDa
NXT1 nuclear transport factor 2-like export factor 1
OSR2 odd-skipped related transciption factor 2
OXSM 3-oxoacyl-ACP synthase, mitochondrial
PCF11 PCF11 cleavage and polyadenylation factor subunit
PEX11B peroxisomal biogenesis factor 11 beta
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PLK2 polo-like kinase 2
PNRC1 proline-rich nuclear receptor coactivator 1
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
RAB20 RAB20, member RAS oncogene family
RANBP6 RAN binding protein 6
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM7 RNA binding motif protein 7
RGS16 regulator of G-protein signaling 16
RHOB ras homolog family member B
RND3 Rho family GTPase 3
RNF113A ring finger protein 113A
RNF139 ring finger protein 139
RPP38 ribonuclease P/MRP 38kDa subunit
SEC24B SEC24 family member B
SERTAD2 SERTA domain containing 2
SETD1B SET domain containing 1B
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC38A2 solute carrier family 38, member 2
SMAD7 SMAD family member 7
SPATA2L spermatogenesis associated 2-like
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRIB1 tribbles pseudokinase 1
TRIM13 tripartite motif containing 13
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TSC22D1 TSC22 domain family, member 1
TXNIP thioredoxin interacting protein
URGCP upregulator of cell proliferation
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
ZBED5 zinc finger, BED-type containing 5
ZBTB24 zinc finger and BTB domain containing 24
ZBTB3 zinc finger and BTB domain containing 3
ZNF14 zinc finger protein 14
ZNF165 zinc finger protein 165
ZNF189 zinc finger protein 189
ZNF217 zinc finger protein 217
ZNF267 zinc finger protein 267
ZNF273 zinc finger protein 273
ZNF302 zinc finger protein 302
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF443 zinc finger protein 443
ZNF85 zinc finger protein 85