darkened coat color Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description amount and distribution of yellow pigment (phaeomelanin) relative to black or brown pigment (eumelanin) is decreased when compared to wild-type agouti (Mammalian Phenotype Ontology, MP_0005409)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005409
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Genes

16 gene mutations causing the darkened coat color phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ASIP agouti signaling protein
ATRN attractin
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CUX1 cut-like homeobox 1
DRD2 dopamine receptor D2
EDAR ectodysplasin A receptor
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
MITF microphthalmia-associated transcription factor
OCA2 oculocutaneous albinism II
PEPD peptidase D
SOX18 SRY (sex determining region Y)-box 18
TMEM79 transmembrane protein 79
TP53 tumor protein p53