damaged dna binding Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Interacting selectively and non-covalently with damaged DNA. (Gene Ontology, GO_0003684)
External Link http://amigo.geneontology.org/amigo/term/GO:0003684
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Genes

56 genes performing the damaged dna binding molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APTX aprataxin
BRCA1 breast cancer 1, early onset
CRY2 cryptochrome circadian clock 2
CUL4B cullin 4B
DDB1 damage-specific DNA binding protein 1, 127kDa
DDB2 damage-specific DNA binding protein 2, 48kDa
ERCC1 excision repair cross-complementation group 1
ERCC3 excision repair cross-complementation group 3
ERCC4 excision repair cross-complementation group 4
FANCG Fanconi anemia, complementation group G
FEN1 flap structure-specific endonuclease 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
H2AFX H2A histone family, member X
HMGB1 high mobility group box 1
HMGB2 high mobility group box 2
MGMT O-6-methylguanine-DNA methyltransferase
MPG N-methylpurine-DNA glycosylase
MSH2 mutS homolog 2
MSH3 mutS homolog 3
MSH4 mutS homolog 4
MSH5 mutS homolog 5
MSH6 mutS homolog 6
NBN nibrin
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NEIL2 nei endonuclease VIII-like 2 (E. coli)
NEIL3 nei endonuclease VIII-like 3 (E. coli)
OGG1 8-oxoguanine DNA glycosylase
PNKP polynucleotide kinase 3'-phosphatase
POLB polymerase (DNA directed), beta
POLH polymerase (DNA directed), eta
POLI polymerase (DNA directed) iota
POLK polymerase (DNA directed) kappa
POLQ polymerase (DNA directed), theta
RAD1 RAD1 checkpoint DNA exonuclease
RAD18 RAD18 E3 ubiquitin protein ligase
RAD23A RAD23 homolog A (S. cerevisiae)
RAD23B RAD23 homolog B (S. cerevisiae)
RAD51 RAD51 recombinase
RBBP8 retinoblastoma binding protein 8
REV1 REV1, polymerase (DNA directed)
RPA1 replication protein A1, 70kDa
RPA2 replication protein A2, 32kDa
RPA3 replication protein A3, 14kDa
RPS3 ribosomal protein S3
RUVBL2 RuvB-like AAA ATPase 2
TDG thymine-DNA glycosylase
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TP63 tumor protein p63
TP73 tumor protein p73
XPA xeroderma pigmentosum, complementation group A
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6