damage Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Similar Terms
Downloads & Tools

Genes

343 proteins co-occuring with the biological term damage in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
AATF apoptosis antagonizing transcription factor
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACACA acetyl-CoA carboxylase alpha
ACACB acetyl-CoA carboxylase beta
ACLY ATP citrate lyase
AICDA activation-induced cytidine deaminase
AKT1 v-akt murine thymoma viral oncogene homolog 1
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APLF aprataxin and PNKP like factor
APTX aprataxin
ARAF A-Raf proto-oncogene, serine/threonine kinase
ATF1 activating transcription factor 1
ATF2 activating transcription factor 2
ATF4 activating transcription factor 4
ATG5 autophagy related 5
ATM ATM serine/threonine kinase
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATR ATR serine/threonine kinase
ATRIP ATR interacting protein
AURKA aurora kinase A
AVEN apoptosis, caspase activation inhibitor
BAD BCL2-associated agonist of cell death
BARD1 BRCA1 associated RING domain 1
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCLAF1 BCL2-associated transcription factor 1
BID BH3 interacting domain death agonist
BLM Bloom syndrome, RecQ helicase-like
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C1QBP complement component 1, q subcomponent binding protein
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CBX1 chromobox homolog 1
CBX4 chromobox homolog 4
CCDC6 coiled-coil domain containing 6
CCND1 cyclin D1
CDC20 cell division cycle 20
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDC25C cell division cycle 25C
CDC27 cell division cycle 27
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK5 cyclin-dependent kinase 5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CDT1 chromatin licensing and DNA replication factor 1
CENPA centromere protein A
CEP164 centrosomal protein 164kDa
CFL1 cofilin 1 (non-muscle)
CHD4 chromodomain helicase DNA binding protein 4
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHMP4C charged multivesicular body protein 4C
CHUK conserved helix-loop-helix ubiquitous kinase
CLSPN claspin
CNN3 calponin 3, acidic
COPS6 COP9 signalosome subunit 6
COX2
CREB1 cAMP responsive element binding protein 1
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CRYAB crystallin, alpha B
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYCS cytochrome c, somatic
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DAPK1 death-associated protein kinase 1
DAXX death-domain associated protein
DBF4 DBF4 zinc finger
DCK deoxycytidine kinase
DCLRE1C DNA cross-link repair 1C
DDIT3 DNA-damage-inducible transcript 3
DNM1L dynamin 1-like
DPYSL2 dihydropyrimidinase-like 2
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
E2F1 E2F transcription factor 1
E2F3 E2F transcription factor 3
EEF2 eukaryotic translation elongation factor 2
EEF2K eukaryotic elongation factor 2 kinase
EGFR epidermal growth factor receptor
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELAVL1 ELAV like RNA binding protein 1
EP300 E1A binding protein p300
EPB41 erythrocyte membrane protein band 4.1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC3 excision repair cross-complementation group 3
ERCC6 excision repair cross-complementation group 6
ERRFI1 ERBB receptor feedback inhibitor 1
ESR1 estrogen receptor 1
EWSR1 EWS RNA-binding protein 1
EXO1 exonuclease 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FANCA Fanconi anemia, complementation group A
FANCD2 Fanconi anemia, complementation group D2
FANCE Fanconi anemia, complementation group E
FBXO31 F-box protein 31
FEN1 flap structure-specific endonuclease 1
FHIT fragile histidine triad
FLT3 fms-related tyrosine kinase 3
FOXM1 forkhead box M1
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXO4 forkhead box O4
FUS FUS RNA binding protein
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GTSE1 G-2 and S-phase expressed 1
H2AFX H2A histone family, member X
H3F3A H3 histone, family 3A
H3F3B H3 histone, family 3B (H3.3B)
HELB helicase (DNA) B
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST1H1C histone cluster 1, H1c
HIST1H2AI histone cluster 1, H2ai
HIST1H2BN histone cluster 1, H2bn
HIST1H3A histone cluster 1, H3a
HMGB1 high mobility group box 1
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HORMAD1 HORMA domain containing 1
HORMAD2 HORMA domain containing 2
HSPB1 heat shock 27kDa protein 1
HSPB6 heat shock protein, alpha-crystallin-related, B6
HTT huntingtin
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
ING1 inhibitor of growth family, member 1
INSR insulin receptor
IRF3 interferon regulatory factor 3
IRS1 insulin receptor substrate 1
JAK1 Janus kinase 1
JUN jun proto-oncogene
JUND jun D proto-oncogene
KAT5 K(lysine) acetyltransferase 5
KHSRP KH-type splicing regulatory protein
KIF11 kinesin family member 11
KMT2A lysine (K)-specific methyltransferase 2A
KRT8 keratin 8, type II
LATS2 large tumor suppressor kinase 2
LCK LCK proto-oncogene, Src family tyrosine kinase
LIG1 ligase I, DNA, ATP-dependent
LRP1 low density lipoprotein receptor-related protein 1
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K4 mitogen-activated protein kinase kinase 4
MAP2K6 mitogen-activated protein kinase kinase 6
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPT microtubule-associated protein tau
MARS methionyl-tRNA synthetase
MCC mutated in colorectal cancers
MCL1 myeloid cell leukemia 1
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MCTS1 malignant T cell amplified sequence 1
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MEN1 multiple endocrine neoplasia I
MET MET proto-oncogene, receptor tyrosine kinase
MIP major intrinsic protein of lens fiber
MITF microphthalmia-associated transcription factor
MLH1 mutL homolog 1
MLKL mixed lineage kinase domain-like
MORC2 MORC family CW-type zinc finger 2
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MVP major vault protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYOD1 myogenic differentiation 1
NABP2 nucleic acid binding protein 2
NBN nibrin
NCF1 neutrophil cytosolic factor 1
NEFL neurofilament, light polypeptide
NEK11 NIMA-related kinase 11
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NHEJ1 nonhomologous end-joining factor 1
NKX3-1 NK3 homeobox 1
NOS1 nitric oxide synthase 1 (neuronal)
NOS3 nitric oxide synthase 3 (endothelial cell)
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR1H2 nuclear receptor subfamily 1, group H, member 2
ORC1 origin recognition complex, subunit 1
ORC2 origin recognition complex, subunit 2
PARK2 parkin RBR E3 ubiquitin protein ligase
PARN poly(A)-specific ribonuclease
PARP1 poly (ADP-ribose) polymerase 1
PARP10 poly (ADP-ribose) polymerase family, member 10
PCNA proliferating cell nuclear antigen
PDX1 pancreatic and duodenal homeobox 1
PHF20 PHD finger protein 20
PIDD1 p53-induced death domain protein 1
PINK1 PTEN induced putative kinase 1
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PLCG1 phospholipase C, gamma 1
PLK1 polo-like kinase 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
PNKP polynucleotide kinase 3'-phosphatase
POLH polymerase (DNA directed), eta
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PRDX1 peroxiredoxin 1
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCB protein kinase C, beta
PRKCE protein kinase C, epsilon
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRPF19 pre-mRNA processing factor 19
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAD1 RAD1 checkpoint DNA exonuclease
RAD17 RAD17 homolog (S. pombe)
RAD18 RAD18 E3 ubiquitin protein ligase
RAD50 RAD50 homolog (S. cerevisiae)
RAD51 RAD51 recombinase
RAD52 RAD52 homolog (S. cerevisiae)
RAD9A RAD9 homolog A (S. pombe)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAG2 recombination activating gene 2
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RB1 retinoblastoma 1
RBBP8 retinoblastoma binding protein 8
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RIPK3 receptor-interacting serine-threonine kinase 3
RNF20 ring finger protein 20, E3 ubiquitin protein ligase
RNF40 ring finger protein 40, E3 ubiquitin protein ligase
RPA2 replication protein A2, 32kDa
RPS3 ribosomal protein S3
RPS6 ribosomal protein S6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RRM2 ribonucleotide reductase M2
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
SETMAR SET domain and mariner transposase fusion gene
SFN stratifin
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIAH1 siah E3 ubiquitin protein ligase 1
SIAH2 siah E3 ubiquitin protein ligase 2
SIRT1 sirtuin 1
SIRT2 sirtuin 2
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SMC1A structural maintenance of chromosomes 1A
SMC3 structural maintenance of chromosomes 3
SP1 Sp1 transcription factor
SPTA1 spectrin, alpha, erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK11 serine/threonine kinase 11
STK3 serine/threonine kinase 3
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
SYN1 synapsin I
SYP synaptophysin
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAOK1 TAO kinase 1
TAOK3 TAO kinase 3
TDP1 tyrosyl-DNA phosphodiesterase 1
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TERF2 telomeric repeat binding factor 2
THOC5 THO complex 5
THRAP3 thyroid hormone receptor associated protein 3
TICRR TOPBP1-interacting checkpoint and replication regulator
TLK1 tousled-like kinase 1
TOP1 topoisomerase (DNA) I
TOP2A topoisomerase (DNA) II alpha 170kDa
TOPBP1 topoisomerase (DNA) II binding protein 1
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TP63 tumor protein p63
TP73 tumor protein p73
TRIM28 tripartite motif containing 28
TSC2 tuberous sclerosis 2
TTC5 tetratricopeptide repeat domain 5
TTK TTK protein kinase
TWIST1 twist family bHLH transcription factor 1
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
UHRF1 ubiquitin-like with PHD and ring finger domains 1
UIMC1 ubiquitin interaction motif containing 1
USF1 upstream transcription factor 1
USP1 ubiquitin specific peptidase 1
USP10 ubiquitin specific peptidase 10
USP28 ubiquitin specific peptidase 28
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VCP valosin containing protein
VDAC1 voltage-dependent anion channel 1
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIM vimentin
VRK1 vaccinia related kinase 1
WEE1 WEE1 G2 checkpoint kinase
WHSC1 Wolf-Hirschhorn syndrome candidate 1
WRN Werner syndrome, RecQ helicase-like
WWC1 WW and C2 domain containing 1
XPA xeroderma pigmentosum, complementation group A
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YAP1 Yes-associated protein 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB17 zinc finger and BTB domain containing 17
ZBTB4 zinc finger and BTB domain containing 4
ZNF420 zinc finger protein 420
ZNHIT1 zinc finger, HIT-type containing 1