cytoplasmic stress granule Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. (Gene Ontology, GO_0010494)
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Genes

221 proteins co-occuring with the cytoplasmic stress granule cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 2.56448
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 2.44436
PABPC1 poly(A) binding protein, cytoplasmic 1 1.90008
FUS FUS RNA binding protein 1.71684
ATXN2 ataxin 2 1.59141
DCP1A decapping mRNA 1A 1.56617
RASA1 RAS p21 protein activator (GTPase activating protein) 1 1.51074
CAPRIN1 cell cycle associated protein 1 1.51074
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 1.47457
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.44629
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 1.42429
ELAVL1 ELAV like RNA binding protein 1 1.41643
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) 1.4041
DCP2 decapping mRNA 2 1.40075
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 1.35266
TARDBP TAR DNA binding protein 1.32329
EIF4E eukaryotic translation initiation factor 4E 1.29103
TSPO translocator protein (18kDa) 1.28836
XRN1 5'-3' exoribonuclease 1 1.2793
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 1.20653
AGO2 argonaute RISC catalytic component 2 1.14853
YBX1 Y box binding protein 1 1.13829
SAMD4A sterile alpha motif domain containing 4A 1.11276
PUM1 pumilio RNA-binding family member 1 1.10002
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) 1.07359
FXR1 fragile X mental retardation, autosomal homolog 1 1.06448
TDRD3 tudor domain containing 3 1.0569
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 1.05085
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 1.0418
LSM12 LSM12 homolog (S. cerevisiae) 0.982932
RC3H2 ring finger and CCCH-type domains 2 0.973714
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.969848
C9ORF72 chromosome 9 open reading frame 72 0.967437
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.946857
DCP1B decapping mRNA 1B 0.938322
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 0.936432
STAU1 staufen double-stranded RNA binding protein 1 0.923259
ZNF318 zinc finger protein 318 0.883782
CASC3 cancer susceptibility candidate 3 0.877791
USP10 ubiquitin specific peptidase 10 0.877791
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 0.863528
CPEB1 cytoplasmic polyadenylation element binding protein 1 0.858014
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 0.841023
MAPKBP1 mitogen-activated protein kinase binding protein 1 0.83322
EIF4A1 eukaryotic translation initiation factor 4A1 0.832761
KHSRP KH-type splicing regulatory protein 0.830007
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.825877
SERBP1 SERPINE1 mRNA binding protein 1 0.803396
ATXN2L ataxin 2-like 0.802479
ADARB1 adenosine deaminase, RNA-specific, B1 0.775014
UBQLN2 ubiquilin 2 0.772275
LARP4B La ribonucleoprotein domain family, member 4B 0.763162
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 0.763162
RBM42 RNA binding motif protein 42 0.759978
IFIH1 interferon induced with helicase C domain 1 0.751357
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.747737
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 0.729284
CIRBP cold inducible RNA binding protein 0.727941
PUM2 pumilio RNA-binding family member 2 0.724812
MEX3B mex-3 RNA binding family member B 0.715458
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.714126
SPATS2L spermatogenesis associated, serine-rich 2-like 0.711908
RC3H1 ring finger and CCCH-type domains 1 0.700423
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 0.685517
WDR62 WD repeat domain 62 0.67463
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.67246
RPS23 ribosomal protein S23 0.670292
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 0.662503
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 0.659913
CELF1 CUGBP, Elav-like family member 1 0.655602
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 0.64958
TPRKB TP53RK binding protein 0.648291
EIF4B eukaryotic translation initiation factor 4B 0.648291
DZIP1 DAZ interacting zinc finger protein 1 0.644858
SRSF3 serine/arginine-rich splicing factor 3 0.638434
ANG angiogenin, ribonuclease, RNase A family, 5 0.636723
MSI1 musashi RNA-binding protein 1 0.632024
EIF3B eukaryotic translation initiation factor 3, subunit B 0.626483
PRR5L proline rich 5 like 0.620954
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 0.61968
TNRC6C trinucleotide repeat containing 6C 0.61968
LSM1 LSM1, U6 small nuclear RNA associated 0.613318
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 0.606128
AGO1 argonaute RISC catalytic component 1 0.603596
GIGYF2 GRB10 interacting GYF protein 2 0.595593
DHPS deoxyhypusine synthase 0.593072
HSF1 heat shock transcription factor 1 0.588456
RBM4 RNA binding motif protein 4 0.580086
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.577164
MEX3C mex-3 RNA binding family member C 0.575078
EDC3 enhancer of mRNA decapping 3 0.574244
MSI2 musashi RNA-binding protein 2 0.571329
GBP3 guanylate binding protein 3 0.570496
EIF4E2 eukaryotic translation initiation factor 4E family member 2 0.569248
PKP3 plakophilin 3 0.558871
PATL1 protein associated with topoisomerase II homolog 1 (yeast) 0.556387
DND1 DND microRNA-mediated repression inhibitor 1 0.555559
SMN2 survival of motor neuron 2, centromeric 0.554732
TBC1D24 TBC1 domain family, member 24 0.553078
NANOS3 nanos homolog 3 (Drosophila) 0.551012
SH2D3C SH2 domain containing 3C 0.536594
WDFY1 WD repeat and FYVE domain containing 1 0.528388
TDRD6 tudor domain containing 6 0.515308
RRM2 ribonucleotide reductase M2 0.510011
MEX3D mex-3 RNA binding family member D 0.509604
RRM1 ribonucleotide reductase M1 0.507163
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 0.507163
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 0.502288
ZNF692 zinc finger protein 692 0.50107
PARP15 poly (ADP-ribose) polymerase family, member 15 0.49661
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.49418
ARHGAP8 Rho GTPase activating protein 8 0.489327
VCP valosin containing protein 0.486904
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 0.481258
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase 0.480453
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.479245
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.477233
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.47442
PRMT1 protein arginine methyltransferase 1 0.470406
ZBP1 Z-DNA binding protein 1 0.470005
PCBP2 poly(rC) binding protein 2 0.468802
EWSR1 EWS RNA-binding protein 1 0.461599
RBPMS RNA binding protein with multiple splicing 0.458803
RPL28 ribosomal protein L28 0.454019
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 0.441312
CNTN4 contactin 4 0.441312
HSPA4 heat shock 70kDa protein 4 0.432224
TSPAN2 tetraspanin 2 0.427497
HABP4 hyaluronan binding protein 4 0.420428
UFD1L ubiquitin fusion degradation 1 like (yeast) 0.420036
CPEB4 cytoplasmic polyadenylation element binding protein 4 0.418077
SMN1 survival of motor neuron 1, telomeric 0.410649
CNOT6 CCR4-NOT transcription complex, subunit 6 0.404804
EDC4 enhancer of mRNA decapping 4 0.401304
DERA deoxyribose-phosphate aldolase (putative) 0.397811
CCAR1 cell division cycle and apoptosis regulator 1 0.388909
MAEL maelstrom spermatogenic transposon silencer 0.380429
ATE1 arginyltransferase 1 0.37966
ZFP36L1 ZFP36 ring finger protein-like 1 0.374283
MIR25 microRNA 25 0.374283
ZC3H12D zinc finger CCCH-type containing 12D 0.371599
CERKL ceramide kinase-like 0.368153
PTBP1 polypyrimidine tract binding protein 1 0.366623
PDCD10 programmed cell death 10 0.365859
UBL4A ubiquitin-like 4A 0.361659
FMR1 fragile X mental retardation 1 0.360133
IFNL2 interferon, lambda 2 0.358609
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 0.357086
ZC3H12A zinc finger CCCH-type containing 12A 0.353662
DAZAP2 DAZ associated protein 2 0.348725
USP18 ubiquitin specific peptidase 18 0.348725
MOV10 Mov10 RISC complex RNA helicase 0.347587
CELF2 CUGBP, Elav-like family member 2 0.344935
CALR calreticulin 0.343799
MIR10B microRNA 10b 0.340017
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.340017
PKP1 plakophilin 1 0.334356
ILF3 interleukin enhancer binding factor 3, 90kDa 0.329461
EIF4H eukaryotic translation initiation factor 4H 0.324951
TDRD1 tudor domain containing 1 0.32345
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 0.322325
FBXO7 F-box protein 7 0.321201
CCNF cyclin F 0.318579
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.29994
POU4F3 POU class 4 homeobox 3 0.295119
RPS6 ribosomal protein S6 0.294748
EEF1B2 eukaryotic translation elongation factor 1 beta 2 0.292157
MIRLET7B microRNA let-7b 0.288091
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.284769
HDAC6 histone deacetylase 6 0.284032
PQBP1 polyglutamine binding protein 1 0.279245
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.278141
EIF3CL eukaryotic translation initiation factor 3, subunit C-like 0.277774
PARG poly (ADP-ribose) glycohydrolase 0.274835
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.273367
EIF3C eukaryotic translation initiation factor 3, subunit C 0.26166
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 0.260931
ZFP36 ZFP36 ring finger protein 0.257289
AFM afamin 0.253653
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 0.252564
EIF3F eukaryotic translation initiation factor 3, subunit F 0.24894
QKI QKI, KH domain containing, RNA binding 0.247492
PARN poly(A)-specific ribonuclease 0.247492
RBM14 RNA binding motif protein 14 0.24713
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.246407
PLIN4 perilipin 4 0.244962
SECISBP2 SECIS binding protein 2 0.238837
SQSTM1 sequestosome 1 0.237401
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.235249
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1 0.232744
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.229176
RNASEH2A ribonuclease H2, subunit A 0.226331
SPAG5 sperm associated antigen 5 0.217511
MAPK8 mitogen-activated protein kinase 8 0.217511
PLAA phospholipase A2-activating protein 0.210894
ELAVL4 ELAV like neuron-specific RNA binding protein 4 0.210549
CDA cytidine deaminase 0.209169
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.206423
FXR2 fragile X mental retardation, autosomal homolog 2 0.198325
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.197993
NUMB numb homolog (Drosophila) 0.196999
VEZF1 vascular endothelial zinc finger 1 0.194698
RNASET2 ribonuclease T2 0.189539
YBX3 Y box binding protein 3 0.18516
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) 0.184241
SRP9P1 signal recognition particle 9 pseudogene 1 0.182122
SRP9 signal recognition particle 9kDa 0.182122
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.180045
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.179167
OGN osteoglycin 0.175745
SRPK1 SRSF protein kinase 1 0.17141
HTT huntingtin 0.170888
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 0.168349
MORF4 mortality factor 4 (pseudogene) 0.167366
EIF4A3 eukaryotic translation initiation factor 4A3 0.16233
MAGOHB mago-nashi homolog B (Drosophila) 0.162117
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) 0.159074
GRB7 growth factor receptor-bound protein 7 0.158882
ARL2 ADP-ribosylation factor-like 2 0.15776
IGF2 insulin-like growth factor 2 0.157397
NPAS4 neuronal PAS domain protein 4 0.156513