cytoplasmic pattern recognition receptor signaling pathway in response to virus Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm. Cytosolic PRRs such as RIG-I (DDX58) and MDA-5 (IFIH1) detect RNA synthesized during active viral replication and trigger a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines. (Gene Ontology, GO_0039528)
External Link http://amigo.geneontology.org/amigo/term/GO:0039528
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Genes

6 genes participating in the cytoplasmic pattern recognition receptor signaling pathway in response to virus biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
IFIH1 interferon induced with helicase C domain 1
IRF3 interferon regulatory factor 3
IRF7 interferon regulatory factor 7
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
MAVS mitochondrial antiviral signaling protein