cytolytic granule Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A specialized secretory lysosome that is present in cells with cytolytic capability such as cytotoxic T lymphocytes and natural killer cells. Cytolytic granules mediate the storage and regulated excretion of lytic molecules for killing of target cells. (Gene Ontology, GO_0044194)
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Genes

4 proteins localized to the cytolytic granule cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
STXBP2 syntaxin binding protein 2 0.663342
PRF1 perforin 1 (pore forming protein) 0.237908
RNF19B ring finger protein 19B 0.03318
LAMP1 lysosomal-associated membrane protein 1 0.03318