cyproterone-6806 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the cyproterone-6806 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ADGRA2 adhesion G protein-coupled receptor A2
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AHSP alpha hemoglobin stabilizing protein
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
APOC4 apolipoprotein C-IV
ATN1 atrophin 1
BCL6 B-cell CLL/lymphoma 6
BIN1 bridging integrator 1
C14ORF79 chromosome 14 open reading frame 79
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CCL27 chemokine (C-C motif) ligand 27
CDCP1 CUB domain containing protein 1
CDH18 cadherin 18, type 2
CDK13 cyclin-dependent kinase 13
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CLCN4 chloride channel, voltage-sensitive 4
CLEC4A C-type lectin domain family 4, member A
CRTAC1 cartilage acidic protein 1
CRYGC crystallin, gamma C
CSF1 colony stimulating factor 1 (macrophage)
CTSE cathepsin E
CYLD cylindromatosis (turban tumor syndrome)
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYTH1 cytohesin 1
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DTX2 deltex 2, E3 ubiquitin ligase
EFNB3 ephrin-B3
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
F2RL2 coagulation factor II (thrombin) receptor-like 2
FGF18 fibroblast growth factor 18
FPR1 formyl peptide receptor 1
FRZB frizzled-related protein
GLP2R glucagon-like peptide 2 receptor
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HAS2 hyaluronan synthase 2
HIST1H4E histone cluster 1, H4e
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
ICA1 islet cell autoantigen 1, 69kDa
IGL immunoglobulin lambda locus
IL1B interleukin 1, beta
KDM4B lysine (K)-specific demethylase 4B
KHSRP KH-type splicing regulatory protein
KIAA0125 KIAA0125
KIF21B kinesin family member 21B
LAMC2 laminin, gamma 2
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LOC100131532 uncharacterized LOC100131532
LPL lipoprotein lipase
MAN2A2 mannosidase, alpha, class 2A, member 2
MID1 midline 1
MINK1 misshapen-like kinase 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MTMR7 myotubularin related protein 7
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NF1 neurofibromin 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NOL12 nucleolar protein 12
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
NUP54 nucleoporin 54kDa
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
ONECUT2 one cut homeobox 2
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OVOL1 ovo-like zinc finger 1
PDCD6 programmed cell death 6
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLXDC1 plexin domain containing 1
PPP1R37 protein phosphatase 1, regulatory subunit 37
PROSC proline synthetase co-transcribed homolog (bacterial)
PSG6 pregnancy specific beta-1-glycoprotein 6
PSORS1C1 psoriasis susceptibility 1 candidate 1
RAVER2 ribonucleoprotein, PTB-binding 2
REM1 RAS (RAD and GEM)-like GTP-binding 1
RNF122 ring finger protein 122
RPL23AP32 ribosomal protein L23a pseudogene 32
RSU1 Ras suppressor protein 1
RUSC2 RUN and SH3 domain containing 2
SAMD9 sterile alpha motif domain containing 9
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SNTA1 syntrophin, alpha 1
SPRR2B small proline-rich protein 2B
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TFF2 trefoil factor 2
TNNT2 troponin T type 2 (cardiac)
TP63 tumor protein p63
UNC13A unc-13 homolog A (C. elegans)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
XYLB xylulokinase homolog (H. influenzae)
ZBTB17 zinc finger and BTB domain containing 17
ZFP64 ZFP64 zinc finger protein
ZNF862 zinc finger protein 862
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABHD17B abhydrolase domain containing 17B
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
ALS2CL ALS2 C-terminal like
APOD apolipoprotein D
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL15 ADP-ribosylation factor-like 15
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ATAD5 ATPase family, AAA domain containing 5
BBS7 Bardet-Biedl syndrome 7
BMP4 bone morphogenetic protein 4
C14ORF93 chromosome 14 open reading frame 93
C1ORF159 chromosome 1 open reading frame 159
C5ORF28 chromosome 5 open reading frame 28
CARD8 caspase recruitment domain family, member 8
CCP110 centriolar coiled coil protein 110kDa
CD2AP CD2-associated protein
CDK3 cyclin-dependent kinase 3
CDR2L cerebellar degeneration-related protein 2-like
CEP85 centrosomal protein 85kDa
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLSPN claspin
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
FBXL2 F-box and leucine-rich repeat protein 2
FBXO31 F-box protein 31
FCHO1 FCH domain only 1
FMO4 flavin containing monooxygenase 4
FRS2 fibroblast growth factor receptor substrate 2
GCHFR GTP cyclohydrolase I feedback regulator
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPALPP1 GPALPP motifs containing 1
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPR27 G protein-coupled receptor 27
GSTTP1 glutathione S-transferase theta pseudogene 1
GTF2I general transcription factor IIi
HAUS6 HAUS augmin-like complex, subunit 6
HIST1H4C histone cluster 1, H4c
HIST1H4D histone cluster 1, H4d
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INO80D INO80 complex subunit D
KCTD20 potassium channel tetramerization domain containing 20
KLF2 Kruppel-like factor 2
KLHL25 kelch-like family member 25
LACTB2 lactamase, beta 2
LHX6 LIM homeobox 6
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAST3 microtubule associated serine/threonine kinase 3
MBIP MAP3K12 binding inhibitory protein 1
MCOLN3 mucolipin 3
METTL16 methyltransferase like 16
MFF mitochondrial fission factor
MTMR11 myotubularin related protein 11
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFE2L3 nuclear factor, erythroid 2-like 3
NT5E 5'-nucleotidase, ecto (CD73)
NUP62CL nucleoporin 62kDa C-terminal like
PARD6A par-6 family cell polarity regulator alpha
PCDHB3 protocadherin beta 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
PRICKLE3 prickle homolog 3 (Drosophila)
PRR4 proline rich 4 (lacrimal)
PTCD2 pentatricopeptide repeat domain 2
QTRT1 queuine tRNA-ribosyltransferase 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RP2 retinitis pigmentosa 2 (X-linked recessive)
SAYSD1 SAYSVFN motif domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SH2D4A SH2 domain containing 4A
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNHG20 small nucleolar RNA host gene 20
SSBP3 single stranded DNA binding protein 3
TAOK1 TAO kinase 1
TMEM104 transmembrane protein 104
TMEM121 transmembrane protein 121
TRABD TraB domain containing
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UFSP2 UFM1-specific peptidase 2
XK X-linked Kx blood group
ZBTB25 zinc finger and BTB domain containing 25
ZBTB48 zinc finger and BTB domain containing 48
ZFP30 ZFP30 zinc finger protein
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF286A zinc finger protein 286A
ZNF492 zinc finger protein 492