cycloserine-7134 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the cycloserine-7134 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSM3 acyl-CoA synthetase medium-chain family member 3
ADRBK1 adrenergic, beta, receptor kinase 1
AEN apoptosis enhancing nuclease
ANXA2P1 annexin A2 pseudogene 1
ARHGAP35 Rho GTPase activating protein 35
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAD5 ATPase family, AAA domain containing 5
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BICD1 bicaudal D homolog 1 (Drosophila)
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF30 chromosome 11 open reading frame 30
C18ORF25 chromosome 18 open reading frame 25
CA5B carbonic anhydrase VB, mitochondrial
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDK17 cyclin-dependent kinase 17
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CENPJ centromere protein J
CIB2 calcium and integrin binding family member 2
CISH cytokine inducible SH2-containing protein
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
COL7A1 collagen, type VII, alpha 1
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
DENND2A DENN/MADD domain containing 2A
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOK2 docking protein 2, 56kDa
DVL2 dishevelled segment polarity protein 2
ECM1 extracellular matrix protein 1
EDRF1 erythroid differentiation regulatory factor 1
EGF epidermal growth factor
FAM193B family with sequence similarity 193, member B
FCMR Fc fragment of IgM receptor
FDX1 ferredoxin 1
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GPATCH2L G patch domain containing 2-like
GPER1 G protein-coupled estrogen receptor 1
GRAMD4 GRAM domain containing 4
HAMP hepcidin antimicrobial peptide
HDAC7 histone deacetylase 7
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HNRNPL heterogeneous nuclear ribonucleoprotein L
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KDM6A lysine (K)-specific demethylase 6A
KIF5C kinesin family member 5C
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
LIMK2 LIM domain kinase 2
MAN2C1 mannosidase, alpha, class 2C, member 1
MAP7 microtubule-associated protein 7
MARS methionyl-tRNA synthetase
METTL5 methyltransferase like 5
MVK mevalonate kinase
NCAPH2 non-SMC condensin II complex, subunit H2
NMB neuromedin B
NPFFR1 neuropeptide FF receptor 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
ONECUT2 one cut homeobox 2
ORAI2 ORAI calcium release-activated calcium modulator 2
PCDHGB5 protocadherin gamma subfamily B, 5
PCNX pecanex homolog (Drosophila)
PEX5 peroxisomal biogenesis factor 5
PHKA2 phosphorylase kinase, alpha 2 (liver)
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLXNA2 plexin A2
PPARD peroxisome proliferator-activated receptor delta
PRKCA protein kinase C, alpha
RAB27B RAB27B, member RAS oncogene family
RABEPK Rab9 effector protein with kelch motifs
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
SCAPER S-phase cyclin A-associated protein in the ER
SHANK2 SH3 and multiple ankyrin repeat domains 2
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SPRR1A small proline-rich protein 1A
SREBF2 sterol regulatory element binding transcription factor 2
SSH3 slingshot protein phosphatase 3
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUGP1 SURP and G patch domain containing 1
TEF thyrotrophic embryonic factor
THBS1 thrombospondin 1
THOC5 THO complex 5
TMC7 transmembrane channel-like 7
TRADD TNFRSF1A-associated via death domain
TRAF4 TNF receptor-associated factor 4
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TTC38 tetratricopeptide repeat domain 38
TUBB2B tubulin, beta 2B class IIb
ULK2 unc-51 like autophagy activating kinase 2
VEZT vezatin, adherens junctions transmembrane protein
WDFY3 WD repeat and FYVE domain containing 3
YIPF2 Yip1 domain family, member 2
ZFPM2 zinc finger protein, FOG family member 2

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADCY7 adenylate cyclase 7
AMPD2 adenosine monophosphate deaminase 2
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APLP1 amyloid beta (A4) precursor-like protein 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAK1 BCL2-antagonist/killer 1
BIK BCL2-interacting killer (apoptosis-inducing)
BIRC3 baculoviral IAP repeat containing 3
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
COG4 component of oligomeric golgi complex 4
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CXCL2 chemokine (C-X-C motif) ligand 2
CXORF56 chromosome X open reading frame 56
DBR1 debranching RNA lariats 1
DCLRE1B DNA cross-link repair 1B
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EVPL envoplakin
FABP4 fatty acid binding protein 4, adipocyte
FAM127B family with sequence similarity 127, member B
FAM155A family with sequence similarity 155, member A
FCHSD2 FCH and double SH3 domains 2
GDAP2 ganglioside induced differentiation associated protein 2
GRWD1 glutamate-rich WD repeat containing 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H2AE histone cluster 1, H2ae
HIST1H3B histone cluster 1, H3b
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
INCENP inner centromere protein antigens 135/155kDa
IREB2 iron-responsive element binding protein 2
IRF6 interferon regulatory factor 6
KIAA0513 KIAA0513
KIAA0556 KIAA0556
KRT15 keratin 15, type I
KRT6A keratin 6A, type II
LINS lines homolog (Drosophila)
MB myoglobin
MMP13 matrix metallopeptidase 13
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
OSBPL11 oxysterol binding protein-like 11
OTUD3 OTU deubiquitinase 3
PAQR4 progestin and adipoQ receptor family member IV
PLD2 phospholipase D2
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
RAB3A RAB3A, member RAS oncogene family
RBBP5 retinoblastoma binding protein 5
RECQL4 RecQ protein-like 4
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SERTAD3 SERTA domain containing 3
SETD8 SET domain containing (lysine methyltransferase) 8
SIX1 SIX homeobox 1
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC31A2 solute carrier family 31 (copper transporter), member 2
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SOX12 SRY (sex determining region Y)-box 12
SREK1IP1 SREK1-interacting protein 1
ST5 suppression of tumorigenicity 5
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STBD1 starch binding domain 1
STK16 serine/threonine kinase 16
SUGCT succinyl-CoA:glutarate-CoA transferase
SYNE2 spectrin repeat containing, nuclear envelope 2
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TENM4 teneurin transmembrane protein 4
TGS1 trimethylguanosine synthase 1
TMEM38B transmembrane protein 38B
TMOD3 tropomodulin 3 (ubiquitous)
TOR4A torsin family 4, member A
TPST2 tyrosylprotein sulfotransferase 2
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZBTB3 zinc finger and BTB domain containing 3
ZC4H2 zinc finger, C4H2 domain containing
ZDHHC18 zinc finger, DHHC-type containing 18
ZHX2 zinc fingers and homeoboxes 2
ZMAT5 zinc finger, matrin-type 5
ZNF189 zinc finger protein 189
ZNF696 zinc finger protein 696
ZNF816 zinc finger protein 816
ZXDC ZXD family zinc finger C