cyclopentolate-6132 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the cyclopentolate-6132 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADARB1 adenosine deaminase, RNA-specific, B1
AGGF1 angiogenic factor with G patch and FHA domains 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AMPH amphiphysin
ANGEL2 angel homolog 2 (Drosophila)
ANP32C acidic (leucine-rich) nuclear phosphoprotein 32 family, member C
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
B9D2 B9 protein domain 2
BCL3 B-cell CLL/lymphoma 3
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C1QTNF3 C1q and tumor necrosis factor related protein 3
C22ORF46 chromosome 22 open reading frame 46
C4BPA complement component 4 binding protein, alpha
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CASC1 cancer susceptibility candidate 1
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC71 coiled-coil domain containing 71
CD59 CD59 molecule, complement regulatory protein
CD6 CD6 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CES3 carboxylesterase 3
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLEC3B C-type lectin domain family 3, member B
CNIH3 cornichon family AMPA receptor auxiliary protein 3
COL10A1 collagen, type X, alpha 1
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
ERBB4 erb-b2 receptor tyrosine kinase 4
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FBXO31 F-box protein 31
FGD1 FYVE, RhoGEF and PH domain containing 1
FGFR1 fibroblast growth factor receptor 1
FGL1 fibrinogen-like 1
FLOT1 flotillin 1
FRMD1 FERM domain containing 1
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GAP43 growth associated protein 43
GM2A GM2 ganglioside activator
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GRM1 glutamate receptor, metabotropic 1
GRTP1 growth hormone regulated TBC protein 1
HAMP hepcidin antimicrobial peptide
HLA-DOA major histocompatibility complex, class II, DO alpha
HOXD1 homeobox D1
KCNE5 potassium channel, voltage gated subfamily E regulatory beta subunit 5
KCNK10 potassium channel, two pore domain subfamily K, member 10
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KLHL3 kelch-like family member 3
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRT24 keratin 24, type I
KYNU kynureninase
LRP6 low density lipoprotein receptor-related protein 6
MEP1B meprin A, beta
MLH3 mutL homolog 3
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NFIB nuclear factor I/B
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OPTN optineurin
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PDE4DIP phosphodiesterase 4D interacting protein
PDZD2 PDZ domain containing 2
PELO pelota homolog (Drosophila)
PER3 period circadian clock 3
PNOC prepronociceptin
POFUT1 protein O-fucosyltransferase 1
RAB6B RAB6B, member RAS oncogene family
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RUNDC3A RUN domain containing 3A
RXRB retinoid X receptor, beta
SAMD4A sterile alpha motif domain containing 4A
SETBP1 SET binding protein 1
SH3BP1 SH3-domain binding protein 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIGLEC8 sialic acid binding Ig-like lectin 8
SKAP1 src kinase associated phosphoprotein 1
SLIT3 slit homolog 3 (Drosophila)
SORBS1 sorbin and SH3 domain containing 1
SOX4 SRY (sex determining region Y)-box 4
SSPN sarcospan
SSX3 synovial sarcoma, X breakpoint 3
SUGP1 SURP and G patch domain containing 1
SV2B synaptic vesicle glycoprotein 2B
TACR1 tachykinin receptor 1
TBX10 T-box 10
THSD7A thrombospondin, type I, domain containing 7A
TMPRSS3 transmembrane protease, serine 3
TRIM10 tripartite motif containing 10
TRPC2 transient receptor potential cation channel, subfamily C, member 2, pseudogene
TSKS testis-specific serine kinase substrate
TSKU tsukushi, small leucine rich proteoglycan
TTC38 tetratricopeptide repeat domain 38
TUBG2 tubulin, gamma 2
WDR55 WD repeat domain 55
WTAP Wilms tumor 1 associated protein
WWC1 WW and C2 domain containing 1
ZNF668 zinc finger protein 668

decreased expression

Symbol Name
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
BIK BCL2-interacting killer (apoptosis-inducing)
BIRC3 baculoviral IAP repeat containing 3
BSPRY B-box and SPRY domain containing
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C17ORF80 chromosome 17 open reading frame 80
CBR3 carbonyl reductase 3
CBX8 chromobox homolog 8
CCDC106 coiled-coil domain containing 106
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD82 CD82 molecule
CLCF1 cardiotrophin-like cytokine factor 1
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CORT cortistatin
CRABP2 cellular retinoic acid binding protein 2
CRMP1 collapsin response mediator protein 1
CTAGE9 CTAGE family, member 9
CYBRD1 cytochrome b reductase 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DNM3 dynamin 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EYA3 EYA transcriptional coactivator and phosphatase 3
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GK3P glycerol kinase 3 pseudogene
GUSBP3 glucuronidase, beta pseudogene 3
HDAC7 histone deacetylase 7
HIRA histone cell cycle regulator
HIST1H1T histone cluster 1, H1t
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AM histone cluster 1, H2am
HIST1H3G histone cluster 1, H3g
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0319L KIAA0319-like
KLHL26 kelch-like family member 26
KPTN kaptin (actin binding protein)
LHFP lipoma HMGIC fusion partner
LOC100287590 uncharacterized LOC100287590
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MBOAT2 membrane bound O-acyltransferase domain containing 2
METRN meteorin, glial cell differentiation regulator
MOCS3 molybdenum cofactor synthesis 3
MXD3 MAX dimerization protein 3
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OMG oligodendrocyte myelin glycoprotein
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PDE12 phosphodiesterase 12
PDGFD platelet derived growth factor D
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
POLL polymerase (DNA directed), lambda
POM121 POM121 transmembrane nucleoporin
PORCN porcupine homolog (Drosophila)
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RAB33B RAB33B, member RAS oncogene family
RHOH ras homolog family member H
RPAP2 RNA polymerase II associated protein 2
RPL13P5 ribosomal protein L13 pseudogene 5
RRAS related RAS viral (r-ras) oncogene homolog
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH2D4A SH2 domain containing 4A
SLC22A14 solute carrier family 22, member 14
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC41A3 solute carrier family 41, member 3
SPATA2L spermatogenesis associated 2-like
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAS2R10 taste receptor, type 2, member 10
TBXAS1 thromboxane A synthase 1 (platelet)
TEX15 testis expressed 15
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM120B transmembrane protein 120B
TMEM209 transmembrane protein 209
TMEM246 transmembrane protein 246
TNS2 tensin 2
TRIM25 tripartite motif containing 25
TRIM68 tripartite motif containing 68
TSPAN13 tetraspanin 13
WDR4 WD repeat domain 4
YY2 YY2 transcription factor
ZBTB22 zinc finger and BTB domain containing 22
ZFP37 ZFP37 zinc finger protein
ZNF276 zinc finger protein 276
ZNF324 zinc finger protein 324
ZNF493 zinc finger protein 493
ZNF552 zinc finger protein 552