cyclic adenosine monophosphate-5533 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the cyclic adenosine monophosphate-5533 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACPP acid phosphatase, prostate
AKAP9 A kinase (PRKA) anchor protein 9
AMBRA1 autophagy/beclin-1 regulator 1
AOC2 amine oxidase, copper containing 2 (retina-specific)
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARL4D ADP-ribosylation factor-like 4D
AXIN1 axin 1
BAX BCL2-associated X protein
BCO1 beta-carotene oxygenase 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CCDC71 coiled-coil domain containing 71
CD1E CD1e molecule
CD300C CD300c molecule
CDC14B cell division cycle 14B
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLUAP1 clusterin associated protein 1
COL1A1 collagen, type I, alpha 1
COL5A2 collagen, type V, alpha 2
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
DDIT3 DNA-damage-inducible transcript 3
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DST dystonin
DVL3 dishevelled segment polarity protein 3
ELP6 elongator acetyltransferase complex subunit 6
EPHA1 EPH receptor A1
EPS8L1 EPS8-like 1
EVI5 ecotropic viral integration site 5
FBXL6 F-box and leucine-rich repeat protein 6
FBXL8 F-box and leucine-rich repeat protein 8
FBXO4 F-box protein 4
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GALT galactose-1-phosphate uridylyltransferase
HBS1L HBS1-like translational GTPase
HIRA histone cell cycle regulator
HNMT histamine N-methyltransferase
HRH1 histamine receptor H1
ICA1 islet cell autoantigen 1, 69kDa
IGFBP3 insulin-like growth factor binding protein 3
IGLJ3 immunoglobulin lambda joining 3
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRS2 insulin receptor substrate 2
ITGB5 integrin, beta 5
ITSN1 intersectin 1 (SH3 domain protein)
KCNK5 potassium channel, two pore domain subfamily K, member 5
KIF13A kinesin family member 13A
KLHL35 kelch-like family member 35
LRP6 low density lipoprotein receptor-related protein 6
MAN2A2 mannosidase, alpha, class 2A, member 2
MED15 mediator complex subunit 15
MIP major intrinsic protein of lens fiber
MPO myeloperoxidase
MSR1 macrophage scavenger receptor 1
NBEAL2 neurobeachin-like 2
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NCLN nicalin
NEK9 NIMA-related kinase 9
NF1 neurofibromin 1
NFX1 nuclear transcription factor, X-box binding 1
NFYA nuclear transcription factor Y, alpha
NGDN neuroguidin, EIF4E binding protein
NID1 nidogen 1
OLFM1 olfactomedin 1
PAPPA2 pappalysin 2
PBX2 pre-B-cell leukemia homeobox 2
PCCA propionyl CoA carboxylase, alpha polypeptide
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POLL polymerase (DNA directed), lambda
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PSD3 pleckstrin and Sec7 domain containing 3
PSG4 pregnancy specific beta-1-glycoprotein 4
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPRD protein tyrosine phosphatase, receptor type, D
RAB35 RAB35, member RAS oncogene family
RAI2 retinoic acid induced 2
RASAL1 RAS protein activator like 1 (GAP1 like)
RPGR retinitis pigmentosa GTPase regulator
RUFY3 RUN and FYVE domain containing 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SIRT3 sirtuin 3
SIX1 SIX homeobox 1
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SNX29 sorting nexin 29
SOAT2 sterol O-acyltransferase 2
SPHK2 sphingosine kinase 2
TBXA2R thromboxane A2 receptor
THAP9 THAP domain containing 9
TICAM1 toll-like receptor adaptor molecule 1
TK2 thymidine kinase 2, mitochondrial
TPMT thiopurine S-methyltransferase
TTLL3 tubulin tyrosine ligase-like family member 3
UCN urocortin
ZFPL1 zinc finger protein-like 1
ZYX zyxin

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ACAD10 acyl-CoA dehydrogenase family, member 10
ADAM15 ADAM metallopeptidase domain 15
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AKIP1 A kinase (PRKA) interacting protein 1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ARL15 ADP-ribosylation factor-like 15
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BBC3 BCL2 binding component 3
BBS1 Bardet-Biedl syndrome 1
BCL9 B-cell CLL/lymphoma 9
BIRC7 baculoviral IAP repeat containing 7
BTF3P12 basic transcription factor 3 pseudogene 12
CA11 carbonic anhydrase XI
CAPN5 calpain 5
CENPO centromere protein O
CHAF1B chromatin assembly factor 1, subunit B (p60)
CIC capicua transcriptional repressor
CLEC4E C-type lectin domain family 4, member E
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CTSF cathepsin F
DGKD diacylglycerol kinase, delta 130kDa
DHRS3 dehydrogenase/reductase (SDR family) member 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFNA3 ephrin-A3
ETNK2 ethanolamine kinase 2
EXO5 exonuclease 5
FAM155B family with sequence similarity 155, member B
FAM86C1 family with sequence similarity 86, member C1
FGGY FGGY carbohydrate kinase domain containing
FILIP1L filamin A interacting protein 1-like
FOSL1 FOS-like antigen 1
FPGS folylpolyglutamate synthase
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GID4 GID complex subunit 4
GLS2 glutaminase 2 (liver, mitochondrial)
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H4F histone cluster 1, H4f
HP1BP3 heterochromatin protein 1, binding protein 3
IDI2-AS1 IDI2 antisense RNA 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL15RA interleukin 15 receptor, alpha
IMPACT impact RWD domain protein
IRF1 interferon regulatory factor 1
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LMO2 LIM domain only 2 (rhombotin-like 1)
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRP5L low density lipoprotein receptor-related protein 5-like
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MANBA mannosidase, beta A, lysosomal
MAP1S microtubule-associated protein 1S
MFSD11 major facilitator superfamily domain containing 11
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MSI1 musashi RNA-binding protein 1
NFE2L3 nuclear factor, erythroid 2-like 3
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
PCDHA9 protocadherin alpha 9
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLAC1 placenta-specific 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIBC2 RIB43A domain with coiled-coils 2
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF170 ring finger protein 170
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SCN1B sodium channel, voltage gated, type I beta subunit
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC12A9 solute carrier family 12, member 9
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC46A3 solute carrier family 46, member 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TGFBR3 transforming growth factor, beta receptor III
TMEM180 transmembrane protein 180
TMEM62 transmembrane protein 62
TTC23 tetratricopeptide repeat domain 23
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
ZBED1 zinc finger, BED-type containing 1
ZMYM3 zinc finger, MYM-type 3
ZNF696 zinc finger protein 696