cyclic adenosine monophosphate-3531 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the cyclic adenosine monophosphate-3531 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ANKLE2 ankyrin repeat and LEM domain containing 2
AP2B1 adaptor-related protein complex 2, beta 1 subunit
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
AQP4 aquaporin 4
C3 complement component 3
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CD47 CD47 molecule
CDC42 cell division cycle 42
CFAP44 cilia and flagella associated protein 44
CLEC2B C-type lectin domain family 2, member B
CLEC4A C-type lectin domain family 4, member A
CRIP1 cysteine-rich protein 1 (intestinal)
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
DDIT3 DNA-damage-inducible transcript 3
DDO D-aspartate oxidase
DLC1 DLC1 Rho GTPase activating protein
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DTNA dystrobrevin, alpha
EML2 echinoderm microtubule associated protein like 2
ENO3 enolase 3 (beta, muscle)
EVA1B eva-1 homolog B (C. elegans)
EWSR1 EWS RNA-binding protein 1
FKBP10 FK506 binding protein 10, 65 kDa
FOXO4 forkhead box O4
FRY furry homolog (Drosophila)
GAL3ST4 galactose-3-O-sulfotransferase 4
GOSR2 golgi SNAP receptor complex member 2
GPM6B glycoprotein M6B
GZMK granzyme K (granzyme 3; tryptase II)
HPX hemopexin
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IFT27 intraflagellar transport 27
IL1B interleukin 1, beta
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IRS4 insulin receptor substrate 4
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JADE2 jade family PHD finger 2
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KRTAP2-4 keratin associated protein 2-4
KRTAP9-9 keratin associated protein 9-9
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
MAN1A2 mannosidase, alpha, class 1A, member 2
MBD3 methyl-CpG binding domain protein 3
MIER2 mesoderm induction early response 1, family member 2
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MKL1 megakaryoblastic leukemia (translocation) 1
MSI1 musashi RNA-binding protein 1
MVB12B multivesicular body subunit 12B
NCAM1 neural cell adhesion molecule 1
NF2 neurofibromin 2 (merlin)
NOP16 NOP16 nucleolar protein
NPM3 nucleophosmin/nucleoplasmin 3
NR2F6 nuclear receptor subfamily 2, group F, member 6
NRF1 nuclear respiratory factor 1
OCA2 oculocutaneous albinism II
OGFR opioid growth factor receptor
PAPOLA poly(A) polymerase alpha
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRDM1 PR domain containing 1, with ZNF domain
PTGIS prostaglandin I2 (prostacyclin) synthase
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RGS12 regulator of G-protein signaling 12
RIN1 Ras and Rab interactor 1
RPS3A ribosomal protein S3A
RUNX1 runt-related transcription factor 1
S100A11 S100 calcium binding protein A11
SCN1B sodium channel, voltage gated, type I beta subunit
SGK2 serum/glucocorticoid regulated kinase 2
SLC35E2 solute carrier family 35, member E2
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SNX13 sorting nexin 13
SOX15 SRY (sex determining region Y)-box 15
SPDEF SAM pointed domain containing ETS transcription factor
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPTBN1 spectrin, beta, non-erythrocytic 1
SSX1 synovial sarcoma, X breakpoint 1
STAT4 signal transducer and activator of transcription 4
STC1 stanniocalcin 1
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
TAOK2 TAO kinase 2
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TCP11L1 t-complex 11, testis-specific-like 1
TFDP3 transcription factor Dp family, member 3
THPO thrombopoietin
TLDC1 TBC/LysM-associated domain containing 1
TLR2 toll-like receptor 2
TNS1 tensin 1
TOP3B topoisomerase (DNA) III beta
WDR62 WD repeat domain 62

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
ADGRG2 adhesion G protein-coupled receptor G2
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ALPK1 alpha-kinase 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BBC3 BCL2 binding component 3
BCORL1 BCL6 corepressor-like 1
C1QTNF3 C1q and tumor necrosis factor related protein 3
C9ORF9 chromosome 9 open reading frame 9
CAMTA1 calmodulin binding transcription activator 1
CASZ1 castor zinc finger 1
CCDC121 coiled-coil domain containing 121
CDK3 cyclin-dependent kinase 3
CIC capicua transcriptional repressor
CISH cytokine inducible SH2-containing protein
CUEDC1 CUE domain containing 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFNA3 ephrin-A3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EMID1 EMI domain containing 1
ERCC6 excision repair cross-complementation group 6
F8 coagulation factor VIII, procoagulant component
FAM222B family with sequence similarity 222, member B
FAM46C family with sequence similarity 46, member C
FBRS fibrosin
FBXL6 F-box and leucine-rich repeat protein 6
FBXW12 F-box and WD repeat domain containing 12
FRMD1 FERM domain containing 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GINS4 GINS complex subunit 4 (Sld5 homolog)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GSTA4 glutathione S-transferase alpha 4
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HIST1H2AK histone cluster 1, H2ak
HOXC10 homeobox C10
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HYI hydroxypyruvate isomerase (putative)
IGFBP6 insulin-like growth factor binding protein 6
INO80D INO80 complex subunit D
IPP intracisternal A particle-promoted polypeptide
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KDM8 lysine (K)-specific demethylase 8
KIAA0894 KIAA0894 protein
LAMA5 laminin, alpha 5
LOC257152 uncharacterized LOC257152
LOC390998 ribosomal protein L10 pseudogene
MAGEA6 melanoma antigen family A6
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MBTD1 mbt domain containing 1
MFAP2 microfibrillar-associated protein 2
MFSD12 major facilitator superfamily domain containing 12
MVD mevalonate (diphospho) decarboxylase
NECAB3 N-terminal EF-hand calcium binding protein 3
NPTX1 neuronal pentraxin I
NT5DC3 5'-nucleotidase domain containing 3
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OSMR oncostatin M receptor
PACS1 phosphofurin acidic cluster sorting protein 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PMP22 peripheral myelin protein 22
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTK6 protein tyrosine kinase 6
RPAP1 RNA polymerase II associated protein 1
RUSC2 RUN and SH3 domain containing 2
SAYSD1 SAYSVFN motif domain containing 1
SCRN3 secernin 3
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC44A1 solute carrier family 44 (choline transporter), member 1
SPAG4 sperm associated antigen 4
STARD3 StAR-related lipid transfer (START) domain containing 3
STIM1 stromal interaction molecule 1
STX1A syntaxin 1A (brain)
SYNGR3 synaptogyrin 3
TIPRL TOR signaling pathway regulator
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TTC30A tetratricopeptide repeat domain 30A
USP20 ubiquitin specific peptidase 20
VAX2 ventral anterior homeobox 2
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
XAB2 XPA binding protein 2
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF365 zinc finger protein 365
ZNF442 zinc finger protein 442
ZNF652 zinc finger protein 652
ZNF701 zinc finger protein 701
ZNF721 zinc finger protein 721
ZNF74 zinc finger protein 74