cyclic adenosine monophosphate-2969 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the cyclic adenosine monophosphate-2969 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADORA3 adenosine A3 receptor
ANKRD6 ankyrin repeat domain 6
AP1M2 adaptor-related protein complex 1, mu 2 subunit
AREG amphiregulin
ATG10 autophagy related 10
ATP11A ATPase, class VI, type 11A
BCL7A B-cell CLL/lymphoma 7A
BCR breakpoint cluster region
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
C5 complement component 5
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CAPN3 calpain 3, (p94)
CCDC132 coiled-coil domain containing 132
CCL20 chemokine (C-C motif) ligand 20
CCR2 chemokine (C-C motif) receptor 2
CD180 CD180 molecule
CDC14A cell division cycle 14A
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDK16 cyclin-dependent kinase 16
CECR1 cat eye syndrome chromosome region, candidate 1
CEP164 centrosomal protein 164kDa
CLCN4 chloride channel, voltage-sensitive 4
CLN3 ceroid-lipofuscinosis, neuronal 3
CLUAP1 clusterin associated protein 1
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL7A1 collagen, type VII, alpha 1
DHRS12 dehydrogenase/reductase (SDR family) member 12
ENG endoglin
EXOG endo/exonuclease (5'-3'), endonuclease G-like
F5 coagulation factor V (proaccelerin, labile factor)
FAM3A family with sequence similarity 3, member A
FCMR Fc fragment of IgM receptor
FKBP5 FK506 binding protein 5
FLT3 fms-related tyrosine kinase 3
FMO5 flavin containing monooxygenase 5
FSTL3 follistatin-like 3 (secreted glycoprotein)
GCFC2 GC-rich sequence DNA-binding factor 2
GLG1 golgi glycoprotein 1
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HUS1 HUS1 checkpoint homolog (S. pombe)
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IL1R2 interleukin 1 receptor, type II
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KAT8 K(lysine) acetyltransferase 8
KLHL28 kelch-like family member 28
MBNL2 muscleblind-like splicing regulator 2
METRN meteorin, glial cell differentiation regulator
MR1 major histocompatibility complex, class I-related
NLRP1 NLR family, pyrin domain containing 1
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
OAZ3 ornithine decarboxylase antizyme 3
OBSL1 obscurin-like 1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PALLD palladin, cytoskeletal associated protein
PARP16 poly (ADP-ribose) polymerase family, member 16
PCNXL2 pecanex-like 2 (Drosophila)
PDE12 phosphodiesterase 12
PER1 period circadian clock 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PKN2 protein kinase N2
PMFBP1 polyamine modulated factor 1 binding protein 1
PRPF18 pre-mRNA processing factor 18
PRSS53 protease, serine, 53
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTCRA pre T-cell antigen receptor alpha
RAB6B RAB6B, member RAS oncogene family
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RET ret proto-oncogene
RGS10 regulator of G-protein signaling 10
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOD ras homolog family member D
RPL13 ribosomal protein L13
RPL13P5 ribosomal protein L13 pseudogene 5
RPS2 ribosomal protein S2
SIRT4 sirtuin 4
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC25A44 solute carrier family 25, member 44
SMAD3 SMAD family member 3
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOCS2 suppressor of cytokine signaling 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
THBS1 thrombospondin 1
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNS1 tensin 1
TROVE2 TROVE domain family, member 2
TSC22D3 TSC22 domain family, member 3
TUBA3C tubulin, alpha 3c
ULK2 unc-51 like autophagy activating kinase 2
USP20 ubiquitin specific peptidase 20
WAPAL wings apart-like homolog (Drosophila)
XIST X inactive specific transcript (non-protein coding)
ZNF154 zinc finger protein 154

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACOX2 acyl-CoA oxidase 2, branched chain
ACP6 acid phosphatase 6, lysophosphatidic
APOBR apolipoprotein B receptor
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BNC2 basonuclin 2
C16ORF59 chromosome 16 open reading frame 59
C1ORF21 chromosome 1 open reading frame 21
C5AR1 complement component 5a receptor 1
C5ORF45 chromosome 5 open reading frame 45
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC71 coiled-coil domain containing 71
CCL2 chemokine (C-C motif) ligand 2
CCL27 chemokine (C-C motif) ligand 27
CD101 CD101 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CES3 carboxylesterase 3
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLGN calmegin
CLSPN claspin
CRELD1 cysteine-rich with EGF-like domains 1
CRY2 cryptochrome circadian clock 2
CXORF56 chromosome X open reading frame 56
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DNASE1L1 deoxyribonuclease I-like 1
DNMBP dynamin binding protein
EVA1B eva-1 homolog B (C. elegans)
EXOSC1 exosome component 1
FBXL7 F-box and leucine-rich repeat protein 7
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FER fer (fps/fes related) tyrosine kinase
FGF9 fibroblast growth factor 9
FGL2 fibrinogen-like 2
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GPR27 G protein-coupled receptor 27
GSDMD gasdermin D
HDAC7 histone deacetylase 7
HHLA3 HERV-H LTR-associating 3
HIST1H1E histone cluster 1, H1e
HIST1H2BO histone cluster 1, H2bo
HIST1H4D histone cluster 1, H4d
HIST3H2A histone cluster 3, H2a
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-DMA major histocompatibility complex, class II, DM alpha
IFNA14 interferon, alpha 14
IPP intracisternal A particle-promoted polypeptide
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LOC390998 ribosomal protein L10 pseudogene
LTC4S leukotriene C4 synthase
MAK male germ cell-associated kinase
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP6D1 MAP6 domain containing 1
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MOCOS molybdenum cofactor sulfurase
MX1 MX dynamin-like GTPase 1
MXD3 MAX dimerization protein 3
NDE1 nudE neurodevelopment protein 1
NUPR1 nuclear protein, transcriptional regulator, 1
OXCT2 3-oxoacid CoA transferase 2
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PCYOX1 prenylcysteine oxidase 1
PGPEP1 pyroglutamyl-peptidase I
PITX2 paired-like homeodomain 2
PROCR protein C receptor, endothelial
RECQL4 RecQ protein-like 4
RHOB ras homolog family member B
RND1 Rho family GTPase 1
RNF122 ring finger protein 122
RNF126P1 ring finger protein 126 pseudogene 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RPL23AP7 ribosomal protein L23a pseudogene 7
SALL2 spalt-like transcription factor 2
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCAMP5 secretory carrier membrane protein 5
SERINC5 serine incorporator 5
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SREBF1 sterol regulatory element binding transcription factor 1
STBD1 starch binding domain 1
TAS2R10 taste receptor, type 2, member 10
TBC1D19 TBC1 domain family, member 19
TMEM180 transmembrane protein 180
TMEM184C transmembrane protein 184C
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TSPYL2 TSPY-like 2
USB1 U6 snRNA biogenesis 1
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF222 zinc finger protein 222
ZNF552 zinc finger protein 552
ZNF747 zinc finger protein 747
ZNF76 zinc finger protein 76