cxcr4 signaling pathway Gene Set

Dataset Biocarta Pathways
Category structural or functional annotations
Type pathway
Description A series of molecular signals initiated by a the C-X-C chemokine type 4 receptor on the surface of a cell binding to one of it's physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription. (Gene Ontology, GO_0038159)
External Link http://cgap.nci.nih.gov/Pathways/BioCarta/h_cxcr4Pathway
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11 proteins participating in the cxcr4 signaling pathway pathway from the Biocarta Pathways dataset.

Symbol Name
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
HRAS Harvey rat sarcoma viral oncogene homolog
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLCG1 phospholipase C, gamma 1