cutaneous t cell lymphoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A non-Hodgkin's lymphoma that is caused by a mutation of T cells. (Human Disease Ontology, DOID_0060061)
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Genes

342 genes co-occuring with the disease cutaneous t cell lymphoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CD4 CD4 molecule 2.14073
CD7 CD7 molecule 2.06668
HDAC9 histone deacetylase 9 1.84545
IL2 interleukin 2 1.54054
CD5 CD5 molecule 1.45616
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 1.45616
PLS3 plastin 3 1.42674
IL2RA interleukin 2 receptor, alpha 1.40876
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 1.37338
NCAM1 neural cell adhesion molecule 1 1.33763
NAV3 neuron navigator 3 1.29265
CD52 CD52 molecule 1.2521
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1 1.24037
CCL17 chemokine (C-C motif) ligand 17 1.23603
HECA headcase homolog (Drosophila) 1.20396
IFNA1 interferon, alpha 1 1.19877
MDFI MyoD family inhibitor 1.18023
IL7 interleukin 7 1.14687
CCL27 chemokine (C-C motif) ligand 27 1.14517
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.08999
IL15 interleukin 15 1.0362
FOXP3 forkhead box P3 1.03493
CXCL13 chemokine (C-X-C motif) ligand 13 1.02271
OAT ornithine aminotransferase 1.01427
JAK3 Janus kinase 3 1.00457
CXCR3 chemokine (C-X-C motif) receptor 3 0.994861
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.988957
GTSF1 gametocyte specific factor 1 0.986849
ALK anaplastic lymphoma receptor tyrosine kinase 0.957033
ADA adenosine deaminase 0.944521
BCL7A B-cell CLL/lymphoma 7A 0.897051
PNP purine nucleoside phosphorylase 0.876966
IGFL2 IGF-like family member 2 0.873691
TARP TCR gamma alternate reading frame protein 0.867549
ICAM1 intercellular adhesion molecule 1 0.804846
PTPRC protein tyrosine phosphatase, receptor type, C 0.801154
IL31 interleukin 31 0.787623
MBNL1 muscleblind-like splicing regulator 1 0.77207
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 0.771252
TP53 tumor protein p53 0.764718
CCL22 chemokine (C-C motif) ligand 22 0.747204
STAT5A signal transducer and activator of transcription 5A 0.746798
GNG8 guanine nucleotide binding protein (G protein), gamma 8 0.739894
PHYH phytanoyl-CoA 2-hydroxylase 0.735433
CXCL10 chemokine (C-X-C motif) ligand 10 0.727738
GPR137B G protein-coupled receptor 137B 0.726929
IL4 interleukin 4 0.724907
STAT2 signal transducer and activator of transcription 2, 113kDa 0.722077
CCR3 chemokine (C-C motif) receptor 3 0.720461
B3GAT1 beta-1,3-glucuronyltransferase 1 0.714408
CCR7 chemokine (C-C motif) receptor 7 0.711183
CCL26 chemokine (C-C motif) ligand 26 0.710378
NCR1 natural cytotoxicity triggering receptor 1 0.706754
FASLG Fas ligand (TNF superfamily, member 6) 0.70434
CD1A CD1a molecule 0.695905
PRF1 perforin 1 (pore forming protein) 0.695905
EIF3G eukaryotic translation initiation factor 3, subunit G 0.689492
CD68 CD68 molecule 0.689092
DUSP22 dual specificity phosphatase 22 0.687091
ZNF195 zinc finger protein 195 0.681495
LGTN ligatin 0.668742
LAX1 lymphocyte transmembrane adaptor 1 0.668345
CD22 CD22 molecule 0.668345
SCARB2 scavenger receptor class B, member 2 0.664372
KLHL42 kelch-like family member 42 0.658026
HDAC11 histone deacetylase 11 0.658026
STAT4 signal transducer and activator of transcription 4 0.648533
CD36 CD36 molecule (thrombospondin receptor) 0.647743
TRAC T cell receptor alpha constant 0.643404
DEFA3 defensin, alpha 3, neutrophil-specific 0.642615
BCL6 B-cell CLL/lymphoma 6 0.637889
NKIRAS2 NFKB inhibitor interacting Ras-like 2 0.637102
RHOF ras homolog family member F (in filopodia) 0.636315
TRIP13 thyroid hormone receptor interactor 13 0.631991
HDAC1 histone deacetylase 1 0.628457
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.614356
SCARB1 scavenger receptor class B, member 1 0.605372
AHI1 Abelson helper integration site 1 0.595623
NKG7 natural killer cell granule protein 7 0.583941
SELE selectin E 0.581606
SATB1 SATB homeobox 1 0.580828
IL10 interleukin 10 0.58005
LAMP3 lysosomal-associated membrane protein 3 0.570718
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.569941
TOX thymocyte selection-associated high mobility group box 0.569163
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 0.563723
LCK LCK proto-oncogene, Src family tyrosine kinase 0.559839
CD79A CD79a molecule, immunoglobulin-associated alpha 0.550522
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 0.549747
CHL1 cell adhesion molecule L1-like 0.542379
CD83 CD83 molecule 0.53928
ANXA5 annexin A5 0.536957
STAT5B signal transducer and activator of transcription 5B 0.533088
PAX5 paired box 5 0.533088
CCDC68 coiled-coil domain containing 68 0.529608
IRF4 interferon regulatory factor 4 0.529222
IFNA2 interferon, alpha 2 0.529222
SLFN12 schlafen family member 12 0.52729
ICAM3 intercellular adhesion molecule 3 0.52729
B2M beta-2-microglobulin 0.523816
BCL2L1 BCL2-like 1 0.520346
GBP5 guanylate binding protein 5 0.519575
CCL21 chemokine (C-C motif) ligand 21 0.518805
CXCL9 chemokine (C-X-C motif) ligand 9 0.514571
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.505739
CCR6 chemokine (C-C motif) receptor 6 0.495411
HDAC6 histone deacetylase 6 0.491597
LGALS1 lectin, galactoside-binding, soluble, 1 0.487407
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.486646
IL16 interleukin 16 0.480566
SKAP1 src kinase associated phosphoprotein 1 0.46466
GAGE12G G antigen 12G 0.462016
CD40LG CD40 ligand 0.460506
CTAGE5 CTAGE family, member 5 0.455601
PARP1 poly (ADP-ribose) polymerase 1 0.452585
IFI35 interferon-induced protein 35 0.4443
THY1 Thy-1 cell surface antigen 0.442042
SKP1 S-phase kinase-associated protein 1 0.44129
CD209 CD209 molecule 0.439034
ESYT1 extended synaptotagmin-like protein 1 0.437906
EEF2 eukaryotic translation elongation factor 2 0.434524
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.430393
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.427765
PAX2 paired box 2 0.42289
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.42289
LTV1 LTV1 ribosome biogenesis factor 0.421016
NOMO1 NODAL modulator 1 0.420641
PIDD1 p53-induced death domain protein 1 0.418768
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.408666
RAD23B RAD23 homolog B (S. cerevisiae) 0.407545
CTAG2 cancer/testis antigen 2 0.403811
SELL selectin L 0.39598
S100A5 S100 calcium binding protein A5 0.395608
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.394863
TNF tumor necrosis factor 0.391141
TGFB1 transforming growth factor, beta 1 0.389281
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) 0.386308
TSGA10 testis specific, 10 0.384079
TMPO thymopoietin 0.381481
TFRC transferrin receptor 0.379626
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.379626
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.376661
HDAC2 histone deacetylase 2 0.372587
IL32 interleukin 32 0.371107
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.370737
NUDC nudC nuclear distribution protein 0.367779
CD19 CD19 molecule 0.359657
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.359657
CD86 CD86 molecule 0.358551
CD69 CD69 molecule 0.354868
DNM3 dynamin 3 0.353027
RAB10 RAB10, member RAS oncogene family 0.352659
STAT1 signal transducer and activator of transcription 1, 91kDa 0.352291
S100A9 S100 calcium binding protein A9 0.348614
PDLIM7 PDZ and LIM domain 7 (enigma) 0.348246
HLA-B major histocompatibility complex, class I, B 0.346777
STK17B serine/threonine kinase 17b 0.346777
MIR93 microRNA 93 0.345308
CCHCR1 coiled-coil alpha-helical rod protein 1 0.343106
GAGE12F G antigen 12F 0.340906
JUND jun D proto-oncogene 0.335778
HDAC3 histone deacetylase 3 0.333949
CCL20 chemokine (C-C motif) ligand 20 0.328105
IL1A interleukin 1, alpha 0.325187
SPO11 SPO11 meiotic protein covalently bound to DSB 0.325187
CD27 CD27 molecule 0.324823
CDKN2A cyclin-dependent kinase inhibitor 2A 0.322637
CXCR5 chemokine (C-X-C motif) receptor 5 0.319363
CD8A CD8a molecule 0.318272
PCNA proliferating cell nuclear antigen 0.316456
ANGPT4 angiopoietin 4 0.313189
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.312464
SYCP1 synaptonemal complex protein 1 0.308118
BOK BCL2-related ovarian killer 0.307395
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.305587
BCL2L10 BCL2-like 10 (apoptosis facilitator) 0.305226
MAGEA9B melanoma antigen family A9B 0.304142
MAGEA9 melanoma antigen family A9 0.304142
UNC13B unc-13 homolog B (C. elegans) 0.303781
SCPEP1 serine carboxypeptidase 1 0.302698
MICB MHC class I polypeptide-related sequence B 0.300173
GRB2 growth factor receptor-bound protein 2 0.299812
LUZP4 leucine zipper protein 4 0.297291
DNTT DNA nucleotidylexotransferase 0.295492
ING2 inhibitor of growth family, member 2 0.295492
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.289744
CCR8 chemokine (C-C motif) receptor 8 0.285444
EIF3H eukaryotic translation initiation factor 3, subunit H 0.285444
STK24 serine/threonine kinase 24 0.282225
CD164 CD164 molecule, sialomucin 0.280082
MTAP methylthioadenosine phosphorylase 0.280082
HELLS helicase, lymphoid-specific 0.279367
CD160 CD160 molecule 0.279011
PANX2 pannexin 2 0.278654
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.276158
GZMM granzyme M (lymphocyte met-ase 1) 0.274021
MAGEA12 melanoma antigen family A12 0.272597
CNOT8 CCR4-NOT transcription complex, subunit 8 0.271174
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.259477
BAG4 BCL2-associated athanogene 4 0.25877
TLR9 toll-like receptor 9 0.258417
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.258064
BIRC5 baculoviral IAP repeat containing 5 0.252422
ATL2 atlastin GTPase 2 0.25207
RGCC regulator of cell cycle 0.251015
TWIST1 twist family bHLH transcription factor 1 0.250311
IK IK cytokine, down-regulator of HLA II 0.24996
VCAM1 vascular cell adhesion molecule 1 0.248905
PDCD10 programmed cell death 10 0.243995
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.241546
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.240497
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 0.237357
MLANA melan-A 0.23492
ING3 inhibitor of growth family, member 3 0.232489
ICAM2 intercellular adhesion molecule 2 0.231795
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.231448
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.230755
HRAS Harvey rat sarcoma viral oncogene homolog 0.230409
STAB1 stabilin 1 0.229716
MIR21 microRNA 21 0.229024
SYCP3 synaptonemal complex protein 3 0.228679
KRT16 keratin 16, type I 0.227988
RAB2A RAB2A, member RAS oncogene family 0.226607
BAX BCL2-associated X protein 0.225573
H3F3B H3 histone, family 3B (H3.3B) 0.225229
H3F3A H3 histone, family 3A 0.225229
S100A7 S100 calcium binding protein A7 0.224196
CDO1 cysteine dioxygenase type 1 0.223853
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.222136
BCL3 B-cell CLL/lymphoma 3 0.22145
SIRPA signal-regulatory protein alpha 0.219057
MXD4 MAX dimerization protein 4 0.218715
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.217693
HLA-C major histocompatibility complex, class I, C 0.215992
IL17F interleukin 17F 0.214297
IFNE interferon, epsilon 0.214297
TSHB thyroid stimulating hormone, beta 0.212608
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.212271
KLRC1 killer cell lectin-like receptor subfamily C, member 1 0.204923
CCL11 chemokine (C-C motif) ligand 11 0.202946
FOXG1 forkhead box G1 0.200331
AGK acylglycerol kinase 0.198709
MIR223 microRNA 223 0.19742
MKNK1 MAP kinase interacting serine/threonine kinase 1 0.197099
BUB3 BUB3 mitotic checkpoint protein 0.196459
ALPP alkaline phosphatase, placental 0.196139
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 0.195501
DHFR dihydrofolate reductase 0.190476
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.189551
TLR8 toll-like receptor 8 0.189244
MAX MYC associated factor X 0.188938
PLVAP plasmalemma vesicle associated protein 0.186811
SSX4B synovial sarcoma, X breakpoint 4B 0.184424
SSX4 synovial sarcoma, X breakpoint 4 0.184424
PLCG1 phospholipase C, gamma 1 0.183835
CADM1 cell adhesion molecule 1 0.183541
PDPN podoplanin 0.180937
CD40 CD40 molecule, TNF receptor superfamily member 5 0.180652
ACPP acid phosphatase, prostate 0.17952
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.177851
ZNF217 zinc finger protein 217 0.177759
IL17A interleukin 17A 0.177029
ZBTB16 zinc finger and BTB domain containing 16 0.175146
TCHH trichohyalin 0.171785
S100P S100 calcium binding protein P 0.170544
PTPRG protein tyrosine phosphatase, receptor type, G 0.166544
BCL2 B-cell CLL/lymphoma 2 0.166319
HBG2 hemoglobin, gamma G 0.164571
ALPPL2 alkaline phosphatase, placental-like 2 0.162908
JAK1 Janus kinase 1 0.162908
ALPL alkaline phosphatase, liver/bone/kidney 0.162505
CD34 CD34 molecule 0.161331
IL5 interleukin 5 0.160948
CD163 CD163 molecule 0.160203
BAGE2 B melanoma antigen family, member 2 0.160021
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.159124
MIRLET7D microRNA let-7d 0.159124
CXCL12 chemokine (C-X-C motif) ligand 12 0.158434
GAGE1 G antigen 1 0.158266
SLAMF1 signaling lymphocytic activation molecule family member 1 0.143948
EPHA7 EPH receptor A7 0.143707
GLIS2 GLIS family zinc finger 2 0.14339
MICA MHC class I polypeptide-related sequence A 0.143112
OSTC oligosaccharyltransferase complex subunit (non-catalytic) 0.142998
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.142632
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.142506
MAGEC1 melanoma antigen family C1 0.142436
KIF11 kinesin family member 11 0.142342
CCR4 chemokine (C-C motif) receptor 4 0.142175
ACOT7 acyl-CoA thioesterase 7 0.142103
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.142079
HHEX hematopoietically expressed homeobox 0.141962
HCK HCK proto-oncogene, Src family tyrosine kinase 0.141776
SSX1 synovial sarcoma, X breakpoint 1 0.14138
RHOB ras homolog family member B 0.141337
BIN1 bridging integrator 1 0.140871
PKN1 protein kinase N1 0.140863
CD226 CD226 molecule 0.140813
NTS neurotensin 0.140325
CCDC27 coiled-coil domain containing 27 0.139825
FAS Fas cell surface death receptor 0.139764
CLEC2A C-type lectin domain family 2, member A 0.139753
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 0.139702
IFNA21 interferon, alpha 21 0.139372
RBP2 retinol binding protein 2, cellular 0.139351
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.139317
LYZ lysozyme 0.139284
CD207 CD207 molecule, langerin 0.139273
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.13924
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.138917
CD244 CD244 molecule, natural killer cell receptor 2B4 0.138893
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 0.138858
CDSN corneodesmosin 0.138858
ESPN espin 0.138773
IFNA17 interferon, alpha 17 0.1387
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.138676
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.138564
BCL10 B-cell CLL/lymphoma 10 0.138539
STK26 serine/threonine protein kinase 26 0.138489
CD1B CD1b molecule 0.138425
MIR27B microRNA 27b 0.138243
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.138123
ZFYVE9 zinc finger, FYVE domain containing 9 0.137863
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.137607
CISH cytokine inducible SH2-containing protein 0.137607
CFD complement factor D (adipsin) 0.137491
CD1C CD1c molecule 0.13725
PLA2G4D phospholipase A2, group IVD (cytosolic) 0.137112
TCL1A T-cell leukemia/lymphoma 1A 0.137018
CXCR1 chemokine (C-X-C motif) receptor 1 0.137018
THBS4 thrombospondin 4 0.136986
SET SET nuclear proto-oncogene 0.136292
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.135956
HRK harakiri, BCL2 interacting protein 0.135605
KLF10 Kruppel-like factor 10 0.135567
LY75 lymphocyte antigen 75 0.135098
FSCN1 fascin actin-bundling protein 1 0.134936
G6PD glucose-6-phosphate dehydrogenase 0.134916
CD274 CD274 molecule 0.134729
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 0.134559
GPR15 G protein-coupled receptor 15 0.134559
CD58 CD58 molecule 0.134343