crotamiton-3050 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the crotamiton-3050 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ACAN aggrecan
ACRV1 acrosomal vesicle protein 1
ACTA2 actin, alpha 2, smooth muscle, aorta
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide
AGFG2 ArfGAP with FG repeats 2
AGMAT agmatine ureohydrolase (agmatinase)
AIM1L absent in melanoma 1-like
AKR1C4 aldo-keto reductase family 1, member C4
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3
AURKA aurora kinase A
BEND5 BEN domain containing 5
BEST2 bestrophin 2
C11ORF16 chromosome 11 open reading frame 16
C1ORF68 chromosome 1 open reading frame 68
CAMK4 calcium/calmodulin-dependent protein kinase IV
CD22 CD22 molecule
CD24 CD24 molecule
CHGB chromogranin B
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLCA1 chloride channel accessory 1
CLIP4 CAP-GLY domain containing linker protein family, member 4
CRISP2 cysteine-rich secretory protein 2
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DNAI2 dynein, axonemal, intermediate chain 2
DSCAM Down syndrome cell adhesion molecule
DUSP4 dual specificity phosphatase 4
EYA3 EYA transcriptional coactivator and phosphatase 3
FABP3 fatty acid binding protein 3, muscle and heart
FAM49B family with sequence similarity 49, member B
GEMIN7 gem (nuclear organelle) associated protein 7
GFER growth factor, augmenter of liver regeneration
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GPATCH4 G patch domain containing 4
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRM1 glutamate receptor, metabotropic 1
GVINP1 GTPase, very large interferon inducible pseudogene 1
HFE hemochromatosis
HIPK3 homeodomain interacting protein kinase 3
HOXA1 homeobox A1
HOXC11 homeobox C11
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IFI6 interferon, alpha-inducible protein 6
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
IL19 interleukin 19
IL4 interleukin 4
IL7R interleukin 7 receptor
JAG1 jagged 1
KIAA1045 KIAA1045
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MTMR8 myotubularin related protein 8
MUC5B mucin 5B, oligomeric mucus/gel-forming
NPR1 natriuretic peptide receptor 1
NQO1 NAD(P)H dehydrogenase, quinone 1
NR5A1 nuclear receptor subfamily 5, group A, member 1
NR6A1 nuclear receptor subfamily 6, group A, member 1
NRAP nebulin-related anchoring protein
NRG1 neuregulin 1
ONECUT2 one cut homeobox 2
OSBPL10 oxysterol binding protein-like 10
PACS1 phosphofurin acidic cluster sorting protein 1
PAX8 paired box 8
PLEKHS1 pleckstrin homology domain containing, family S member 1
POU5F1B POU class 5 homeobox 1B
PPP1R3A protein phosphatase 1, regulatory subunit 3A
PXDC1 PX domain containing 1
RAP1GAP RAP1 GTPase activating protein
REG1A regenerating islet-derived 1 alpha
SAMD4A sterile alpha motif domain containing 4A
SERHL2 serine hydrolase-like 2
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SPAG6 sperm associated antigen 6
ST7L suppression of tumorigenicity 7 like
STEAP4 STEAP family member 4
TCP10 t-complex 10
TEX41 testis expressed 41 (non-protein coding)
THRB thyroid hormone receptor, beta
TM4SF1 transmembrane 4 L six family member 1
TMOD1 tropomodulin 1
TNP2 transition protein 2 (during histone to protamine replacement)
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1
TRIM3 tripartite motif containing 3
TSKU tsukushi, small leucine rich proteoglycan
TSPAN9 tetraspanin 9
TSPY1 testis specific protein, Y-linked 1
TUBA4B tubulin, alpha 4b
UNC119 unc-119 homolog (C. elegans)
VAV2 vav 2 guanine nucleotide exchange factor
ZFHX3 zinc finger homeobox 3
ZNF518A zinc finger protein 518A

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
AOAH acyloxyacyl hydrolase (neutrophil)
APOL6 apolipoprotein L, 6
ARMCX4 armadillo repeat containing, X-linked 4
ARR3 arrestin 3, retinal (X-arrestin)
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BANK1 B-cell scaffold protein with ankyrin repeats 1
BCAR3 breast cancer anti-estrogen resistance 3
C14ORF105 chromosome 14 open reading frame 105
C7ORF43 chromosome 7 open reading frame 43
C9ORF3 chromosome 9 open reading frame 3
CAMKMT calmodulin-lysine N-methyltransferase
CAPN5 calpain 5
CDHR2 cadherin-related family member 2
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CFAP69 cilia and flagella associated protein 69
CFP complement factor properdin
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
COL19A1 collagen, type XIX, alpha 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DNAH17 dynein, axonemal, heavy chain 17
DZANK1 double zinc ribbon and ankyrin repeat domains 1
ELAVL3 ELAV like neuron-specific RNA binding protein 3
FAM131A family with sequence similarity 131, member A
FBXL2 F-box and leucine-rich repeat protein 2
FGF23 fibroblast growth factor 23
FKBPL FK506 binding protein like
FOXD1 forkhead box D1
GATA4 GATA binding protein 4
GPR85 G protein-coupled receptor 85
HIST1H3G histone cluster 1, H3g
HIST1H4E histone cluster 1, H4e
HSPA1L heat shock 70kDa protein 1-like
IBSP integrin-binding sialoprotein
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL4R interleukin 4 receptor
INCENP inner centromere protein antigens 135/155kDa
KANSL1L KAT8 regulatory NSL complex subunit 1-like
MAGEH1 melanoma antigen family H1
MUC2 mucin 2, oligomeric mucus/gel-forming
NEK11 NIMA-related kinase 11
NIPAL2 NIPA-like domain containing 2
NME8 NME/NM23 family member 8
NOD2 nucleotide-binding oligomerization domain containing 2
NOL10 nucleolar protein 10
NPFFR1 neuropeptide FF receptor 1
OXCT2 3-oxoacid CoA transferase 2
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PADI1 peptidyl arginine deiminase, type I
PADI2 peptidyl arginine deiminase, type II
PARP3 poly (ADP-ribose) polymerase family, member 3
PECR peroxisomal trans-2-enoyl-CoA reductase
PHACTR1 phosphatase and actin regulator 1
PIP prolactin-induced protein
PLAT plasminogen activator, tissue
PMFBP1 polyamine modulated factor 1 binding protein 1
POLL polymerase (DNA directed), lambda
PRICKLE3 prickle homolog 3 (Drosophila)
RAB33A RAB33A, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
REC8 REC8 meiotic recombination protein
RPL23AP32 ribosomal protein L23a pseudogene 32
RPL23AP53 ribosomal protein L23a pseudogene 53
SERINC5 serine incorporator 5
SH2D4A SH2 domain containing 4A
SLAMF7 SLAM family member 7
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC35F6 solute carrier family 35, member F6
STAB2 stabilin 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
THRAP3 thyroid hormone receptor associated protein 3
TIAM2 T-cell lymphoma invasion and metastasis 2
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM242 transmembrane protein 242
TOLLIP toll interacting protein
TONSL tonsoku-like, DNA repair protein
TRAF2 TNF receptor-associated factor 2
TRPS1 trichorhinophalangeal syndrome I
TTLL1 tubulin tyrosine ligase-like family member 1
TTPAL tocopherol (alpha) transfer protein-like
TUBA3C tubulin, alpha 3c
UPP1 uridine phosphorylase 1
WASF3 WAS protein family, member 3
WDR25 WD repeat domain 25
YOD1 YOD1 deubiquitinase
ZBTB22 zinc finger and BTB domain containing 22
ZBTB38 zinc finger and BTB domain containing 38
ZKSCAN8 zinc finger with KRAB and SCAN domains 8
ZNF225 zinc finger protein 225
ZNF286A zinc finger protein 286A
ZNF329 zinc finger protein 329
ZNF345 zinc finger protein 345
ZNF428 zinc finger protein 428
ZNF675 zinc finger protein 675