crohn's disease Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An intestinal disease that involves inflammation located_in intestine. (Human Disease Ontology, DOID_8778)
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Genes

64 genes associated with the disease crohn's disease in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BSN bassoon presynaptic cytomatrix protein
C11ORF30 chromosome 11 open reading frame 30
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CD14 CD14 molecule
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CSF1R colony stimulating factor 1 receptor
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DAO D-amino-acid oxidase
DLG5 discs, large homolog 5 (Drosophila)
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FASLG Fas ligand (TNF superfamily, member 6)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HLA-B major histocompatibility complex, class I, B
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HSPA1B heat shock 70kDa protein 1B
HSPA2 heat shock 70kDa protein 2
ICAM1 intercellular adhesion molecule 1
ICOSLG inducible T-cell co-stimulator ligand
IL10 interleukin 10
IL12B interleukin 12B
IL16 interleukin 16
IL18 interleukin 18
IL1R1 interleukin 1 receptor, type I
IL23R interleukin 23 receptor
IL4 interleukin 4
IL4R interleukin 4 receptor
IRGM immunity-related GTPase family, M
ITLN1 intelectin 1 (galactofuranose binding)
JAK2 Janus kinase 2
LRRK2 leucine-rich repeat kinase 2
LTA lymphotoxin alpha
MST1 macrophage stimulating 1
MUC19 mucin 19, oligomeric
NELL1 NEL-like 1 (chicken)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NKX2-3 NK2 homeobox 3
NOD2 nucleotide-binding oligomerization domain containing 2
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TPMT thiopurine S-methyltransferase
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
ZNF365 zinc finger protein 365