coupled Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

383 genes co-occuring with the biological term coupled in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AATF apoptosis antagonizing transcription factor
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ACYP2 acylphosphatase 2, muscle type
ADAM10 ADAM metallopeptidase domain 10
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ADGRG6 adhesion G protein-coupled receptor G6
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
ADRBK1 adrenergic, beta, receptor kinase 1
AEBP1 AE binding protein 1
AFP alpha-fetoprotein
AKAP5 A kinase (PRKA) anchor protein 5
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALKBH3 alkB, alkylation repair homolog 3 (E. coli)
ALYREF Aly/REF export factor
AMH anti-Mullerian hormone
ANXA2 annexin A2
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APP amyloid beta (A4) precursor protein
APTX aprataxin
AR androgen receptor
ARF6 ADP-ribosylation factor 6
ARSA arylsulfatase A
ASCC3 activating signal cointegrator 1 complex subunit 3
B2M beta-2-microglobulin
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BECN1 beclin 1, autophagy related
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
C3 complement component 3
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAMLG calcium modulating ligand
CAPNS1 calpain, small subunit 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CCKBR cholecystokinin B receptor
CCL2 chemokine (C-C motif) ligand 2
CCNB1 cyclin B1
CCND1 cyclin D1
CCNE1 cyclin E1
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD2BP2 CD2 (cytoplasmic tail) binding protein 2
CD40 CD40 molecule, TNF receptor superfamily member 5
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDKN2B-AS1 CDKN2B antisense RNA 1
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CGA glycoprotein hormones, alpha polypeptide
CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4
CLCN2 chloride channel, voltage-sensitive 2
CLCN4 chloride channel, voltage-sensitive 4
CLCN5 chloride channel, voltage-sensitive 5
CLEC7A C-type lectin domain family 7, member A
CMKLR1 chemerin chemokine-like receptor 1
CNR1 cannabinoid receptor 1 (brain)
CORT cortistatin
CREB1 cAMP responsive element binding protein 1
CRYAA crystallin, alpha A
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTN cortactin
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR5 chemokine (C-X-C motif) receptor 5
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DDIT4 DNA-damage-inducible transcript 4
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DIAPH1 diaphanous-related formin 1
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DSG3 desmoglein 3
DVL3 dishevelled segment polarity protein 3
E2F1 E2F transcription factor 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF2A eukaryotic translation initiation factor 2A, 65kDa
EIF3G eukaryotic translation initiation factor 3, subunit G
EIF4A1 eukaryotic translation initiation factor 4A1
EIF4B eukaryotic translation initiation factor 4B
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ELK1 ELK1, member of ETS oncogene family
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EP300 E1A binding protein p300
EPAS1 endothelial PAS domain protein 1
EPB41 erythrocyte membrane protein band 4.1
EPHA3 EPH receptor A3
ERBB4 erb-b2 receptor tyrosine kinase 4
ESR1 estrogen receptor 1
ESRRA estrogen-related receptor alpha
F2R coagulation factor II (thrombin) receptor
F2RL2 coagulation factor II (thrombin) receptor-like 2
F3 coagulation factor III (thromboplastin, tissue factor)
F8 coagulation factor VIII, procoagulant component
FBP1 fructose-1,6-bisphosphatase 1
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FFAR1 free fatty acid receptor 1
FFAR2 free fatty acid receptor 2
FFAR3 free fatty acid receptor 3
FGR FGR proto-oncogene, Src family tyrosine kinase
FHOD1 formin homology 2 domain containing 1
FLNA filamin A, alpha
FMO1 flavin containing monooxygenase 1
FST follistatin
FYN FYN proto-oncogene, Src family tyrosine kinase
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GALR1 galanin receptor 1
GFAP glial fibrillary acidic protein
GFER growth factor, augmenter of liver regeneration
GH1 growth hormone 1
GH2 growth hormone 2
GHR growth hormone receptor
GJA1 gap junction protein, alpha 1, 43kDa
GJA5 gap junction protein, alpha 5, 40kDa
GJC1 gap junction protein, gamma 1, 45kDa
GJD2 gap junction protein, delta 2, 36kDa
GLP1R glucagon-like peptide 1 receptor
GLP2R glucagon-like peptide 2 receptor
GLRA1 glycine receptor, alpha 1
GLUL glutamate-ammonia ligase
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GNRHR gonadotropin-releasing hormone receptor
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPR161 G protein-coupled receptor 161
GPR35 G protein-coupled receptor 35
GPR55 G protein-coupled receptor 55
GPR87 G protein-coupled receptor 87
GPRASP1 G protein-coupled receptor associated sorting protein 1
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRK5 G protein-coupled receptor kinase 5
GRM5 glutamate receptor, metabotropic 5
HBA1 hemoglobin, alpha 1
HBB hemoglobin, beta
HCRTR1 hypocretin (orexin) receptor 1
HES5 hes family bHLH transcription factor 5
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-B major histocompatibility complex, class I, B
HLA-E major histocompatibility complex, class I, E
HLA-G major histocompatibility complex, class I, G
HMGB1 high mobility group box 1
HP haptoglobin
HRH1 histamine receptor H1
HSPE1 heat shock 10kDa protein 1
HTL high L-leucine transport
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
ICAM1 intercellular adhesion molecule 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFT27 intraflagellar transport 27
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IL10 interleukin 10
IL12RB1 interleukin 12 receptor, beta 1
IL1RL1 interleukin 1 receptor-like 1
IL33 interleukin 33
IL6 interleukin 6
IL6R interleukin 6 receptor
IQGAP1 IQ motif containing GTPase activating protein 1
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KAT8 K(lysine) acetyltransferase 8
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KDR kinase insert domain receptor
KIF11 kinesin family member 11
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
LDLR low density lipoprotein receptor
LEPR leptin receptor
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LHCGR luteinizing hormone/choriogonadotropin receptor
LMNA lamin A/C
LPAR1 lysophosphatidic acid receptor 1
LPXN leupaxin
LRP1 low density lipoprotein receptor-related protein 1
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LTF lactotransferrin
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAOA monoamine oxidase A
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK9 mitogen-activated protein kinase 9
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAVS mitochondrial antiviral signaling protein
MCL1 myeloid cell leukemia 1
MEF2C myocyte enhancer factor 2C
MGMT O-6-methylguanine-DNA methyltransferase
MIR21 microRNA 21
MIR377 microRNA 377
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MRGPRX2 MAS-related GPR, member X2
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
NABP2 nucleic acid binding protein 2
NCF1 neutrophil cytosolic factor 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NISCH nischarin
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NPC2 Niemann-Pick disease, type C2
NPW neuropeptide W
NR1H3 nuclear receptor subfamily 1, group H, member 3
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
OGG1 8-oxoguanine DNA glycosylase
OPN4 opsin 4
ORAI1 ORAI calcium release-activated calcium modulator 1
OVOL1 ovo-like zinc finger 1
OVOL2 ovo-like zinc finger 2
OVOL3 ovo-like zinc finger 3
OXER1 oxoeicosanoid (OXE) receptor 1
OXT oxytocin/neurophysin I prepropeptide
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PAQR6 progestin and adipoQ receptor family member VI
PAQR9 progestin and adipoQ receptor family member IX
PARP1 poly (ADP-ribose) polymerase 1
PCNA proliferating cell nuclear antigen
PDCD1 programmed cell death 1
PGR progesterone receptor
PHB prohibitin
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PITX2 paired-like homeodomain 2
PLAUR plasminogen activator, urokinase receptor
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
PLP1 proteolipid protein 1
PNCK pregnancy up-regulated nonubiquitous CaM kinase
PPARD peroxisome proliferator-activated receptor delta
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRDM1 PR domain containing 1, with ZNF domain
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRF1 perforin 1 (pore forming protein)
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRMT3 protein arginine methyltransferase 3
PRNP prion protein
PRPF6 pre-mRNA processing factor 6
PRSS8 protease, serine, 8
PSAP prosaposin
PSMG3 proteasome (prosome, macropain) assembly chaperone 3
PTGDR prostaglandin D2 receptor (DP)
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGES prostaglandin E synthase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH1R parathyroid hormone 1 receptor
PTH2R parathyroid hormone 2 receptor
PTK7 protein tyrosine kinase 7 (inactive)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRC protein tyrosine phosphatase, receptor type, C
PYCARD PYD and CARD domain containing
RAB10 RAB10, member RAS oncogene family
RAD51 RAD51 recombinase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBL2 retinoblastoma-like 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RGS2 regulator of G-protein signaling 2
RHAG Rh-associated glycoprotein
RHOA ras homolog family member A
RNF20 ring finger protein 20, E3 ubiquitin protein ligase
RNF40 ring finger protein 40, E3 ubiquitin protein ligase
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RRM2 ribonucleotide reductase M2
RTN1 reticulon 1
RXFP1 relaxin/insulin-like family peptide receptor 1
RXFP3 relaxin/insulin-like family peptide receptor 3
RYR1 ryanodine receptor 1 (skeletal)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCN5A sodium channel, voltage gated, type V alpha subunit
SCRIB scribbled planar cell polarity protein
SDC1 syndecan 1
SEC24C SEC24 family member C
SETMAR SET domain and mariner transposase fusion gene
SHOX short stature homeobox
SIRT3 sirtuin 3
SKAP1 src kinase associated phosphoprotein 1
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC46A1 solute carrier family 46 (folate transporter), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMN1 survival of motor neuron 1, telomeric
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNCB synuclein, beta
SNX1 sorting nexin 1
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SP1 Sp1 transcription factor
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPAST spastin
SPHK1 sphingosine kinase 1
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPP1 secreted phosphoprotein 1
SPRR1B small proline-rich protein 1B
SRSF2 serine/arginine-rich splicing factor 2
SSB Sjogren syndrome antigen B (autoantigen La)
SST somatostatin
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAB1 stabilin 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STIM1 stromal interaction molecule 1
STX3 syntaxin 3
STXBP2 syntaxin binding protein 2
TERC telomerase RNA component
TERT telomerase reverse transcriptase
TF transferrin
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THOC1 THO complex 1
THOC2 THO complex 2
THOC3 THO complex 3
TIMP3 TIMP metallopeptidase inhibitor 3
TJP1 tight junction protein 1
TM2D1 TM2 domain containing 1
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TNF tumor necrosis factor
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNNC1 troponin C type 1 (slow)
TNNI3 troponin I type 3 (cardiac)
TP53 tumor protein p53
TPI1 triosephosphate isomerase 1
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TTR transthyretin
UBE2I ubiquitin-conjugating enzyme E2I
UCK1 uridine-cytidine kinase 1
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UXS1 UDP-glucuronate decarboxylase 1
VAV1 vav 1 guanine nucleotide exchange factor
VCAN versican
VEGFA vascular endothelial growth factor A
VIP vasoactive intestinal peptide
VWF von Willebrand factor
XBP1 X-box binding protein 1
YBX1 Y box binding protein 1