corynanthine-4227 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the corynanthine-4227 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP11 A kinase (PRKA) anchor protein 11
ARHGAP10 Rho GTPase activating protein 10
ASIC3 acid sensing (proton gated) ion channel 3
ATXN7L1 ataxin 7-like 1
BAIAP2 BAI1-associated protein 2
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BMP10 bone morphogenetic protein 10
C22ORF31 chromosome 22 open reading frame 31
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHI3L2 chitinase 3-like 2
CNGA1 cyclic nucleotide gated channel alpha 1
CRYGC crystallin, gamma C
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DKFZP434C153 DKFZP434C153 protein
DNASE1L3 deoxyribonuclease I-like 3
DOCK6 dedicator of cytokinesis 6
DSG3 desmoglein 3
EDA ectodysplasin A
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ERP44 endoplasmic reticulum protein 44
ESRRG estrogen-related receptor gamma
ETV6 ets variant 6
FAM49B family with sequence similarity 49, member B
FAM63A family with sequence similarity 63, member A
FAS Fas cell surface death receptor
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FCGBP Fc fragment of IgG binding protein
FHIT fragile histidine triad
FLJ20712 uncharacterized FLJ20712
FOXN3 forkhead box N3
FRMD4A FERM domain containing 4A
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GJA9 gap junction protein, alpha 9, 59kDa
GLRA2 glycine receptor, alpha 2
GPALPP1 GPALPP motifs containing 1
GYPC glycophorin C (Gerbich blood group)
HAP1 huntingtin-associated protein 1
HAS1 hyaluronan synthase 1
HFE hemochromatosis
HOXA1 homeobox A1
HOXB7 homeobox B7
HPN hepsin
IFT27 intraflagellar transport 27
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
ITGB1BP2 integrin beta 1 binding protein (melusin) 2
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1
LOX lysyl oxidase
LPIN2 lipin 2
LPL lipoprotein lipase
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRRTM4 leucine rich repeat transmembrane neuronal 4
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MBD2 methyl-CpG binding domain protein 2
MTRF1L mitochondrial translational release factor 1-like
MYBPC3 myosin binding protein C, cardiac
N4BP1 NEDD4 binding protein 1
NAV3 neuron navigator 3
NF1 neurofibromin 1
NLGN4X neuroligin 4, X-linked
NOX3 NADPH oxidase 3
NPHP1 nephronophthisis 1 (juvenile)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OLIG2 oligodendrocyte lineage transcription factor 2
OXCT2 3-oxoacid CoA transferase 2
PCDH17 protocadherin 17
PDLIM4 PDZ and LIM domain 4
PKNOX1 PBX/knotted 1 homeobox 1
PML promyelocytic leukemia
PNMAL1 paraneoplastic Ma antigen family-like 1
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRAMEF12 PRAME family member 12
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTPRB protein tyrosine phosphatase, receptor type, B
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
PYGO1 pygopus family PHD finger 1
PYHIN1 pyrin and HIN domain family, member 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RECQL5 RecQ protein-like 5
RGS5 regulator of G-protein signaling 5
RPL10L ribosomal protein L10-like
RSG1 REM2 and RAB-like small GTPase 1
SAYSD1 SAYSVFN motif domain containing 1
SIT1 signaling threshold regulating transmembrane adaptor 1
SMO smoothened, frizzled class receptor
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNX29 sorting nexin 29
SV2B synaptic vesicle glycoprotein 2B
TMEM63A transmembrane protein 63A
TNIK TRAF2 and NCK interacting kinase
TUBB1 tubulin, beta 1 class VI
WAPAL wings apart-like homolog (Drosophila)
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF141 zinc finger protein 141
ZNF234 zinc finger protein 234
ZNF345 zinc finger protein 345
ZNF613 zinc finger protein 613
ZNF688 zinc finger protein 688

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ADAM2 ADAM metallopeptidase domain 2
ALPK1 alpha-kinase 1
ANP32A-IT1 ANP32A intronic transcript 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
C11ORF63 chromosome 11 open reading frame 63
C14ORF105 chromosome 14 open reading frame 105
CA5BP1 carbonic anhydrase VB pseudogene 1
CA9 carbonic anhydrase IX
CAPN15 calpain 15
CCL2 chemokine (C-C motif) ligand 2
CDADC1 cytidine and dCMP deaminase domain containing 1
CDHR2 cadherin-related family member 2
CDON cell adhesion associated, oncogene regulated
CFAP45 cilia and flagella associated protein 45
CHM choroideremia (Rab escort protein 1)
CISH cytokine inducible SH2-containing protein
CLCA1 chloride channel accessory 1
CNGB3 cyclic nucleotide gated channel beta 3
CNTLN centlein, centrosomal protein
CTDNEP1 CTD nuclear envelope phosphatase 1
CTSF cathepsin F
CXCL3 chemokine (C-X-C motif) ligand 3
CXCR2 chemokine (C-X-C motif) receptor 2
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DEAF1 DEAF1 transcription factor
DSPP dentin sialophosphoprotein
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERN2 endoplasmic reticulum to nucleus signaling 2
FLJ21369 uncharacterized protein FLJ21369
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GPR1 G protein-coupled receptor 1
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
GRM4 glutamate receptor, metabotropic 4
GRTP1 growth hormone regulated TBC protein 1
GTF2I general transcription factor IIi
HAMP hepcidin antimicrobial peptide
HIST1H2AI histone cluster 1, H2ai
IFNA17 interferon, alpha 17
IL2 interleukin 2
IL36RN interleukin 36 receptor antagonist
JUNB jun B proto-oncogene
KANSL3 KAT8 regulatory NSL complex subunit 3
KLF13 Kruppel-like factor 13
LIME1 Lck interacting transmembrane adaptor 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LRRK1 leucine-rich repeat kinase 1
LTC4S leukotriene C4 synthase
LY6D lymphocyte antigen 6 complex, locus D
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MED15 mediator complex subunit 15
MED9 mediator complex subunit 9
MFGE8 milk fat globule-EGF factor 8 protein
MTSS1L metastasis suppressor 1-like
MYL9 myosin, light chain 9, regulatory
MYO15A myosin XVA
NOTCH4 notch 4
NPFFR1 neuropeptide FF receptor 1
NUP62CL nucleoporin 62kDa C-terminal like
PACS1 phosphofurin acidic cluster sorting protein 1
PDE12 phosphodiesterase 12
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PER3 period circadian clock 3
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PODNL1 podocan-like 1
PRB3 proline-rich protein BstNI subfamily 3
PRICKLE3 prickle homolog 3 (Drosophila)
PRM2 protamine 2
RAB3A RAB3A, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RAPSN receptor-associated protein of the synapse
RIBC2 RIB43A domain with coiled-coils 2
RNF126P1 ring finger protein 126 pseudogene 1
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPH3AL rabphilin 3A-like (without C2 domains)
SBNO2 strawberry notch homolog 2 (Drosophila)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SGK2 serum/glucocorticoid regulated kinase 2
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SMR3A submaxillary gland androgen regulated protein 3A
SP1 Sp1 transcription factor
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SSBP3 single stranded DNA binding protein 3
SUGCT succinyl-CoA:glutarate-CoA transferase
TBC1D17 TBC1 domain family, member 17
TBC1D22B TBC1 domain family, member 22B
TBKBP1 TBK1 binding protein 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFBI transforming growth factor, beta-induced, 68kDa
TIGD6 tigger transposable element derived 6
TLN1 talin 1
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSC22D4 TSC22 domain family, member 4
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
XAB2 XPA binding protein 2
ZFHX3 zinc finger homeobox 3