cortical granule Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A secretory vesicle that is stored under the cell membrane of an egg. These vesicles fuse with the egg plasma membrane as part of egg activation and are part of the block to polyspermy. (Gene Ontology, GO_0060473)
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Genes

96 proteins co-occuring with the cortical granule cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 1.95372
ASTL astacin-like metallo-endopeptidase (M12 family) 1.68055
ZP3 zona pellucida glycoprotein 3 (sperm receptor) 1.4921
ZP1 zona pellucida glycoprotein 1 (sperm receptor) 1.45025
ZP4 zona pellucida glycoprotein 4 1.35978
ITLN2 intelectin 2 1.04783
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.961667
KLK11 kallikrein-related peptidase 11 0.958789
C19ORF26 chromosome 19 open reading frame 26 0.890245
FES FES proto-oncogene, tyrosine kinase 0.871346
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 0.700863
PADI6 peptidyl arginine deiminase, type VI 0.685517
RPH3A rabphilin 3A 0.677673
DNMBP dynamin binding protein 0.615861
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 0.578416
FETUB fetuin B 0.551838
ZFYVE26 zinc finger, FYVE domain containing 26 0.545236
CCNB2 cyclin B2 0.536183
GDF9 growth differentiation factor 9 0.50107
MYLK2 myosin light chain kinase 2 0.470807
JMY junction mediating and regulatory protein, p53 cofactor 0.470807
NPM2 nucleophosmin/nucleoplasmin 2 0.469604
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 0.460401
PPBPP1 pro-platelet basic protein pseudogene 1 0.460001
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 0.454418
ITLN1 intelectin 1 (galactofuranose binding) 0.416902
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.409089
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.409089
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.408699
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.407919
FBXO43 F-box protein 43 0.404804
NACA3P NACA family member 3 pseudogene 0.398587
TREX1 three prime repair exonuclease 1 0.397811
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.392388
OVGP1 oviductal glycoprotein 1, 120kDa 0.389296
SRI sorcin 0.381969
PLVAP plasmalemma vesicle associated protein 0.377738
SMR3B submaxillary gland androgen regulated protein 3B 0.377354
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 0.359371
AKAP8 A kinase (PRKA) anchor protein 8 0.355183
RAB11B RAB11B, member RAS oncogene family 0.351762
PLCZ1 phospholipase C, zeta 1 0.345692
RAB3C RAB3C, member RAS oncogene family 0.345314
LRP5 low density lipoprotein receptor-related protein 5 0.342285
ING3 inhibitor of growth family, member 3 0.336996
CALR calreticulin 0.335864
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.332848
COL11A2P1 collagen, type XI, alpha 2 pseudogene 1 0.332472
COL11A1 collagen, type XI, alpha 1 0.332095
PICALM phosphatidylinositol binding clathrin assembly protein 0.322325
CTSZ cathepsin Z 0.321201
CAMK4 calcium/calmodulin-dependent protein kinase IV 0.319702
CDC42 cell division cycle 42 0.307377
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 0.303283
MYLK myosin light chain kinase 0.298084
RAB43 RAB43, member RAS oncogene family 0.291417
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.288829
ADAM2 ADAM metallopeptidase domain 2 0.28846
ACPP acid phosphatase, prostate 0.282926
LDLR low density lipoprotein receptor 0.277774
PTPRN protein tyrosine phosphatase, receptor type, N 0.275569
MAPK3 mitogen-activated protein kinase 3 0.272633
YES1 YES proto-oncogene 1, Src family tyrosine kinase 0.266774
RAB3B RAB3B, member RAS oncogene family 0.26385
CCNB1 cyclin B1 0.261296
INS insulin 0.258745
ACVR2A activin A receptor, type IIA 0.256197
DNTT DNA nucleotidylexotransferase 0.250751
GAS6 growth arrest-specific 6 0.24713
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.24424
HSF1 heat shock transcription factor 1 0.240996
GPX2 glutathione peroxidase 2 0.231672
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.22385
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 0.210549
PRSS1 protease, serine, 1 (trypsin 1) 0.208481
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.208137
POU5F1B POU class 5 homeobox 1B 0.207794
USP9X ubiquitin specific peptidase 9, X-linked 0.207108
SYT1 synaptotagmin I 0.192746
PRSS3 protease, serine, 3 0.18859
RAP2B RAP2B, member of RAS oncogene family 0.186708
RYR3 ryanodine receptor 3 0.182422
SAR1A secretion associated, Ras related GTPase 1A 0.181524
ARF3 ADP-ribosylation factor 3 0.181227
CPA6 carboxypeptidase A6 0.180634
PLAT plasminogen activator, tissue 0.180339
RAB1B RAB1B, member RAS oncogene family 0.178877
IFI30 interferon, gamma-inducible protein 30 0.178011
ALB albumin 0.17687
SIL1 SIL1 nucleotide exchange factor 0.169859
BMP1 bone morphogenetic protein 1 0.164542
CST4 cystatin S 0.162763
MYH2 myosin, heavy chain 2, skeletal muscle, adult 0.162763
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 0.161693
FURIN furin (paired basic amino acid cleaving enzyme) 0.160863
DNM2 dynamin 2 0.156513