coronary artery disease Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles. (Human Disease Ontology, DOID_3393)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0001677
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Genes

65 genes associated with the coronary artery disease phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
ACTA2 actin, alpha 2, smooth muscle, aorta
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AKT2 v-akt murine thymoma viral oncogene homolog 2
APOA1 apolipoprotein A-I
APOB apolipoprotein B
APOE apolipoprotein E
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BRAF B-Raf proto-oncogene, serine/threonine kinase
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C4A complement component 4A (Rodgers blood group)
CALR calreticulin
CAV1 caveolin 1, caveolae protein, 22kDa
CBS cystathionine-beta-synthase
CLIP2 CAP-GLY domain containing linker protein 2
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
ELN elastin
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FOS FBJ murine osteosarcoma viral oncogene homolog
GLA galactosidase, alpha
GTF2I general transcription factor IIi
GTF2IRD1 GTF2I repeat domain containing 1
HGD homogentisate 1,2-dioxygenase
HLA-B major histocompatibility complex, class I, B
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
IDUA iduronidase, alpha-L-
IL10 interleukin 10
IL12B interleukin 12B
IL12RB2 interleukin 12 receptor, beta 2
IL23R interleukin 23 receptor
JAK2 Janus kinase 2
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
LCAT lecithin-cholesterol acyltransferase
LIMK1 LIM domain kinase 1
LIPC lipase, hepatic
LMNA lamin A/C
LPL lipoprotein lipase
MEFV Mediterranean fever
MLX MLX, MAX dimerization protein
MPL MPL proto-oncogene, thrombopoietin receptor
MYH11 myosin, heavy chain 11, smooth muscle
MYH9 myosin, heavy chain 9, non-muscle
NOD2 nucleotide-binding oligomerization domain containing 2
PPARG peroxisome proliferator-activated receptor gamma
PRTN3 proteinase 3
PTEN phosphatase and tensin homolog
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RFC2 replication factor C (activator 1) 2, 40kDa
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SH2B3 SH2B adaptor protein 3
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
STAT4 signal transducer and activator of transcription 4
TBL2 transducin (beta)-like 2
TET2 tet methylcytosine dioxygenase 2
TLR4 toll-like receptor 4
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TP53 tumor protein p53
WRN Werner syndrome, RecQ helicase-like
ZMPSTE24 zinc metallopeptidase STE24