coronary artery disease; Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles. (Human Disease Ontology, DOID_3393)
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Genes

51 genes associated with the disease coronary artery disease; in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ADAM17 ADAM metallopeptidase domain 17
ADIPOQ adiponectin, C1Q and collagen domain containing
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
APOA1 apolipoprotein A-I
APOA5 apolipoprotein A-V
APOE apolipoprotein E
ARID5B AT rich interactive domain 5B (MRF1-like)
BLVRA biliverdin reductase A
C12ORF43 chromosome 12 open reading frame 43
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CETP cholesteryl ester transfer protein, plasma
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
ESR1 estrogen receptor 1
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
FGB fibrinogen beta chain
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
HMOX1 heme oxygenase 1
HNF1A HNF1 homeobox A
ICAM1 intercellular adhesion molecule 1
IL6 interleukin 6
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
LIPC lipase, hepatic
LPA lipoprotein, Lp(a)
LPAL2 lipoprotein, Lp(a)-like 2, pseudogene
LPL lipoprotein lipase
MCPH1 microcephalin 1
MKL1 megakaryoblastic leukemia (translocation) 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PEAR1 platelet endothelial aggregation receptor 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PON1 paraoxonase 1
PON2 paraoxonase 2
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSRC1 proline/serine-rich coiled-coil 1
SELE selectin E
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLCO1B1 solute carrier organic anion transporter family, member 1B1
TNF tumor necrosis factor
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1