coralyne-6317 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the coralyne-6317 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI2 abl-interactor 2
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARTN artemin
ATXN2L ataxin 2-like
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCL2L11 BCL2-like 11 (apoptosis facilitator)
C1ORF61 chromosome 1 open reading frame 61
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC88A coiled-coil domain containing 88A
CCL27 chemokine (C-C motif) ligand 27
CD4 CD4 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CNR2 cannabinoid receptor 2 (macrophage)
COL7A1 collagen, type VII, alpha 1
CRYGC crystallin, gamma C
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DCAKD dephospho-CoA kinase domain containing
DLX4 distal-less homeobox 4
DSTYK dual serine/threonine and tyrosine protein kinase
EDA ectodysplasin A
EFNA3 ephrin-A3
FAM65B family with sequence similarity 65, member B
FOXG1 forkhead box G1
GABARAPL1 GABA(A) receptor-associated protein like 1
GH1 growth hormone 1
GLB1L galactosidase, beta 1-like
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPC3 glypican 3
GRIP2 glutamate receptor interacting protein 2
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HABP4 hyaluronan binding protein 4
HIST1H2AK histone cluster 1, H2ak
HIST1H3C histone cluster 1, H3c
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKZF1 IKAROS family zinc finger 1 (Ikaros)
ISYNA1 inositol-3-phosphate synthase 1
KIAA1107 KIAA1107
KIFC3 kinesin family member C3
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KRIT1 KRIT1, ankyrin repeat containing
LEF1 lymphoid enhancer-binding factor 1
LRRTM2 leucine rich repeat transmembrane neuronal 2
MAK male germ cell-associated kinase
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MBTPS2 membrane-bound transcription factor peptidase, site 2
MEP1B meprin A, beta
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MST1 macrophage stimulating 1
MTRF1L mitochondrial translational release factor 1-like
NPEPL1 aminopeptidase-like 1
NT5M 5',3'-nucleotidase, mitochondrial
NTSR1 neurotensin receptor 1 (high affinity)
OVGP1 oviductal glycoprotein 1, 120kDa
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PLXNC1 plexin C1
POFUT1 protein O-fucosyltransferase 1
POU5F1B POU class 5 homeobox 1B
PPARD peroxisome proliferator-activated receptor delta
PRSS8 protease, serine, 8
PTK7 protein tyrosine kinase 7 (inactive)
RBM19 RNA binding motif protein 19
RERE arginine-glutamic acid dipeptide (RE) repeats
RGCC regulator of cell cycle
RIN3 Ras and Rab interactor 3
RPP25 ribonuclease P/MRP 25kDa subunit
RUSC2 RUN and SH3 domain containing 2
SCN11A sodium channel, voltage gated, type XI alpha subunit
SH2D3C SH2 domain containing 3C
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC22A14 solute carrier family 22, member 14
SLC46A3 solute carrier family 46, member 3
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SPON1 spondin 1, extracellular matrix protein
SRRT serrate, RNA effector molecule
STAG3 stromal antigen 3
STMN4 stathmin-like 4
STX2 syntaxin 2
TMEM53 transmembrane protein 53
TMPRSS15 transmembrane protease, serine 15
TMSB15A thymosin beta 15a
TRIM62 tripartite motif containing 62
TSSK2 testis-specific serine kinase 2
TTC9 tetratricopeptide repeat domain 9
TTLL5 tubulin tyrosine ligase-like family member 5
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)
WDR1 WD repeat domain 1
WWOX WW domain containing oxidoreductase
YPEL1 yippee-like 1 (Drosophila)
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF76 zinc finger protein 76
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
AVPI1 arginine vasopressin-induced 1
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BRAF B-Raf proto-oncogene, serine/threonine kinase
C17ORF70 chromosome 17 open reading frame 70
C1ORF105 chromosome 1 open reading frame 105
CCDC106 coiled-coil domain containing 106
CHKB choline kinase beta
CIDEC cell death-inducing DFFA-like effector c
CISH cytokine inducible SH2-containing protein
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CRYBA2 crystallin, beta A2
DET1 de-etiolated homolog 1 (Arabidopsis)
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
EIF5A2 eukaryotic translation initiation factor 5A2
ELOVL4 ELOVL fatty acid elongase 4
EN1 engrailed homeobox 1
EPHA4 EPH receptor A4
FMO4 flavin containing monooxygenase 4
FOXN2 forkhead box N2
GFOD1 glucose-fructose oxidoreductase domain containing 1
GMEB1 glucocorticoid modulatory element binding protein 1
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPATCH2L G patch domain containing 2-like
GRAMD1B GRAM domain containing 1B
GRPR gastrin-releasing peptide receptor
HIST1H2AI histone cluster 1, H2ai
HLA-J major histocompatibility complex, class I, J (pseudogene)
HMGB3P1 high mobility group box 3 pseudogene 1
HOXB9 homeobox B9
IDI2-AS1 IDI2 antisense RNA 1
IL4R interleukin 4 receptor
KIAA1549L KIAA1549-like
LNPEP leucyl/cystinyl aminopeptidase
LYPLA2P1 lysophospholipase II pseudogene 1
MAGEF1 melanoma antigen family F1
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha)
MCRS1 microspherule protein 1
MEIS1 Meis homeobox 1
MOXD1 monooxygenase, DBH-like 1
MRPL41 mitochondrial ribosomal protein L41
MRPS18C mitochondrial ribosomal protein S18C
MTERF4 mitochondrial transcription termination factor 4
MUC3A mucin 3A, cell surface associated
MYO9A myosin IXA
NCS1 neuronal calcium sensor 1
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PDGFRL platelet-derived growth factor receptor-like
PER3 period circadian clock 3
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLEKHA6 pleckstrin homology domain containing, family A member 6
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
PRAME preferentially expressed antigen in melanoma
PRR7 proline rich 7 (synaptic)
PSKH1 protein serine kinase H1
PTGES2 prostaglandin E synthase 2
PXMP4 peroxisomal membrane protein 4, 24kDa
REPS2 RALBP1 associated Eps domain containing 2
RIBC2 RIB43A domain with coiled-coils 2
RNF146 ring finger protein 146
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
SERTAD3 SERTA domain containing 3
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SIX1 SIX homeobox 1
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SND1-IT1 SND1 intronic transcript 1
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STAG3L1 stromal antigen 3-like 1 (pseudogene)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TPCN1 two pore segment channel 1
TRAIP TRAF interacting protein
TUBA4B tubulin, alpha 4b
UBQLN4 ubiquilin 4
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
UNC119 unc-119 homolog (C. elegans)
URM1 ubiquitin related modifier 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR18 WD repeat domain 18
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF214 zinc finger protein 214
ZNF324 zinc finger protein 324
ZNF358 zinc finger protein 358
ZNF442 zinc finger protein 442
ZNF592 zinc finger protein 592
ZNF654 zinc finger protein 654