convolamine-7230 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the convolamine-7230 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ADRA1A adrenoceptor alpha 1A
AKAP6 A kinase (PRKA) anchor protein 6
AKR1C2 aldo-keto reductase family 1, member C2
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APLP1 amyloid beta (A4) precursor-like protein 1
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOC4 apolipoprotein C-IV
AQP3 aquaporin 3 (Gill blood group)
ARMCX4 armadillo repeat containing, X-linked 4
ASIC2 acid sensing (proton gated) ion channel 2
ATXN2L ataxin 2-like
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAG4 BCL2-associated athanogene 4
BBS9 Bardet-Biedl syndrome 9
BMP6 bone morphogenetic protein 6
CASP10 caspase 10, apoptosis-related cysteine peptidase
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLCA2 chloride channel accessory 2
CLCN7 chloride channel, voltage-sensitive 7
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CORT cortistatin
CPA1 carboxypeptidase A1 (pancreatic)
CPN2 carboxypeptidase N, polypeptide 2
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSF1R colony stimulating factor 1 receptor
CYHR1 cysteine/histidine-rich 1
DLK2 delta-like 2 homolog (Drosophila)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DOK5 docking protein 5
DRD2 dopamine receptor D2
DTNA dystrobrevin, alpha
ELAC2 elaC ribonuclease Z 2
ERCC2 excision repair cross-complementation group 2
FGF4 fibroblast growth factor 4
FLJ11292
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GRK4 G protein-coupled receptor kinase 4
GSN gelsolin
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HBB hemoglobin, beta
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HN1L hematological and neurological expressed 1-like
HOXB2 homeobox B2
HYAL3 hyaluronoglucosaminidase 3
IDUA iduronidase, alpha-L-
IL27RA interleukin 27 receptor, alpha
IL5RA interleukin 5 receptor, alpha
ITGA10 integrin, alpha 10
ITPK1 inositol-tetrakisphosphate 1-kinase
LAMP1 lysosomal-associated membrane protein 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LUZP1 leucine zipper protein 1
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
METTL7A methyltransferase like 7A
MGC12488
MNDA myeloid cell nuclear differentiation antigen
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
NAAA N-acylethanolamine acid amidase
NCOA2 nuclear receptor coactivator 2
NEURL1 neuralized E3 ubiquitin protein ligase 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NIPAL2 NIPA-like domain containing 2
NPPB natriuretic peptide B
PAX5 paired box 5
PCM1 pericentriolar material 1
PHF7 PHD finger protein 7
PRSS16 protease, serine, 16 (thymus)
PSD3 pleckstrin and Sec7 domain containing 3
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGES prostaglandin E synthase
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRA protein tyrosine phosphatase, receptor type, A
RANBP3 RAN binding protein 3
REEP2 receptor accessory protein 2
SAP30 Sin3A-associated protein, 30kDa
SCGB2A2 secretoglobin, family 2A, member 2
SCN10A sodium channel, voltage gated, type X alpha subunit
SERHL2 serine hydrolase-like 2
SOCS6 suppressor of cytokine signaling 6
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STK3 serine/threonine kinase 3
SYT5 synaptotagmin V
TDRD3 tudor domain containing 3
TMEM19 transmembrane protein 19
TMEM212 transmembrane protein 212
TRA2A transformer 2 alpha homolog (Drosophila)
TRAF3IP3 TRAF3 interacting protein 3
TRIM3 tripartite motif containing 3
TTBK2 tau tubulin kinase 2
VPRBP Vpr (HIV-1) binding protein
WDTC1 WD and tetratricopeptide repeats 1
WSCD1 WSC domain containing 1
YY2 YY2 transcription factor
ZNF222 zinc finger protein 222
ZNF286A zinc finger protein 286A

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
AXIN1 axin 1
AZI2 5-azacytidine induced 2
BACE1 beta-site APP-cleaving enzyme 1
BCORL1 BCL6 corepressor-like 1
BFSP1 beaded filament structural protein 1, filensin
BRPF1 bromodomain and PHD finger containing, 1
C6ORF47 chromosome 6 open reading frame 47
CAMTA1 calmodulin binding transcription activator 1
CAMTA2 calmodulin binding transcription activator 2
CASZ1 castor zinc finger 1
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CDC25A cell division cycle 25A
CDK20 cyclin-dependent kinase 20
CDR2L cerebellar degeneration-related protein 2-like
CEP85 centrosomal protein 85kDa
CFAP69 cilia and flagella associated protein 69
CLCF1 cardiotrophin-like cytokine factor 1
CRLF1 cytokine receptor-like factor 1
DENND4A DENN/MADD domain containing 4A
DNAL4 dynein, axonemal, light chain 4
DSPP dentin sialophosphoprotein
DUSP2 dual specificity phosphatase 2
ELOVL4 ELOVL fatty acid elongase 4
F3 coagulation factor III (thromboplastin, tissue factor)
FAAH fatty acid amide hydrolase
FAM188A family with sequence similarity 188, member A
FBXO2 F-box protein 2
FKBP10 FK506 binding protein 10, 65 kDa
GLB1L2 galactosidase, beta 1-like 2
GPX2 glutathione peroxidase 2
GSTA4 glutathione S-transferase alpha 4
HIST1H1D histone cluster 1, H1d
HMHA1 histocompatibility (minor) HA-1
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL4R interleukin 4 receptor
IRAK4 interleukin-1 receptor-associated kinase 4
KLHL25 kelch-like family member 25
KREMEN2 kringle containing transmembrane protein 2
LHX1 LIM homeobox 1
LY6D lymphocyte antigen 6 complex, locus D
LZTFL1 leucine zipper transcription factor-like 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MANEA mannosidase, endo-alpha
MAPKBP1 mitogen-activated protein kinase binding protein 1
MAST3 microtubule associated serine/threonine kinase 3
MB myoglobin
MCOLN1 mucolipin 1
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MSX1 msh homeobox 1
MUC3A mucin 3A, cell surface associated
MXD3 MAX dimerization protein 3
NBAS neuroblastoma amplified sequence
NECAP2 NECAP endocytosis associated 2
NFE2L3 nuclear factor, erythroid 2-like 3
NLRX1 NLR family member X1
NRSN2 neurensin 2
NUP62CL nucleoporin 62kDa C-terminal like
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PARD6A par-6 family cell polarity regulator alpha
PCDHGB5 protocadherin gamma subfamily B, 5
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLD2 phospholipase D2
PLD3 phospholipase D family, member 3
PTDSS2 phosphatidylserine synthase 2
RAD54L2 RAD54-like 2 (S. cerevisiae)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
SH2B3 SH2B adaptor protein 3
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNORA21 small nucleolar RNA, H/ACA box 21
SPINK4 serine peptidase inhibitor, Kazal type 4
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STARD3 StAR-related lipid transfer (START) domain containing 3
TET3 tet methylcytosine dioxygenase 3
TMEM53 transmembrane protein 53
TNK1 tyrosine kinase, non-receptor, 1
TOM1 target of myb1 (chicken)
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAIP TRAF interacting protein
TRIM5 tripartite motif containing 5
TSPAN15 tetraspanin 15
TTC23 tetratricopeptide repeat domain 23
UBXN6 UBX domain protein 6
VASH2 vasohibin 2
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDR70 WD repeat domain 70
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XYLT2 xylosyltransferase II
ZBTB48 zinc finger and BTB domain containing 48
ZNF205 zinc finger protein 205
ZNF250 zinc finger protein 250
ZNF274 zinc finger protein 274
ZNF552 zinc finger protein 552
ZNF574 zinc finger protein 574