congestive heart failure Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body. (Human Disease Ontology, DOID_6000)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0001635
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Genes

128 genes associated with the congestive heart failure phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ACAD9 acyl-CoA dehydrogenase family, member 9
ACTC1 actin, alpha, cardiac muscle 1
ACVRL1 activin A receptor type II-like 1
ADAMTSL2 ADAMTS-like 2
ADCY5 adenylate cyclase 5
AGGF1 angiogenic factor with G patch and FHA domains 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALMS1 Alstrom syndrome protein 1
APOA1 apolipoprotein A-I
BAG3 BCL2-associated athanogene 3
BAZ1B bromodomain adjacent to zinc finger domain, 1B
CASR calcium-sensing receptor
CAV1 caveolin 1, caveolae protein, 22kDa
CAV3 caveolin 3
CCR6 chemokine (C-C motif) receptor 6
CISD2 CDGSH iron sulfur domain 2
CLIC2 chloride intracellular channel 2
CLIP2 CAP-GLY domain containing linker protein 2
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COX1
COX2
COX3
CP ceruloplasmin (ferroxidase)
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CTGF connective tissue growth factor
DES desmin
DMD dystrophin
DNAJC19 DnaJ (Hsp40) homolog, subfamily C, member 19
DSP desmoplakin
DTNA dystrobrevin, alpha
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
ELAC2 elaC ribonuclease Z 2
ELN elastin
ENG endoglin
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPG5 ectopic P-granules autophagy protein 5 homolog (C. elegans)
EYA4 EYA transcriptional coactivator and phosphatase 4
FBLN5 fibulin 5
FBN1 fibrillin 1
FGD1 FYVE, RhoGEF and PH domain containing 1
FGF23 fibroblast growth factor 23
FLNA filamin A, alpha
FXN frataxin
GATAD1 GATA zinc finger domain containing 1
GBA glucosidase, beta, acid
GDF2 growth differentiation factor 2
GJA1 gap junction protein, alpha 1, 43kDa
GLA galactosidase, alpha
GLB1 galactosidase, beta 1
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GTF2I general transcription factor IIi
GTF2IRD1 GTF2I repeat domain containing 1
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HBA1 hemoglobin, alpha 1
HBA2 hemoglobin, alpha 2
HFE hemochromatosis
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IDS iduronate 2-sulfatase
IGHV4-34 immunoglobulin heavy variable 4-34
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IRF5 interferon regulatory factor 5
JUP junction plakoglobin
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIF1B kinesin family member 1B
LDB3 LIM domain binding 3
LIMK1 LIM domain kinase 1
LMNA lamin A/C
MT-ND4 NADH dehydrogenase, subunit 4 (complex I)
MT-ND5 NADH dehydrogenase, subunit 5 (complex I)
MT-ND6 NADH dehydrogenase, subunit 6 (complex I)
MT-TF tRNA
MT-TH tRNA
MT-TK tRNA
MT-TL1 tRNA
MT-TQ tRNA
MT-TS1 tRNA
MT-TS2 tRNA
MT-TW tRNA
MYD88 myeloid differentiation primary response 88
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYLK2 myosin light chain kinase 2
ND1
PHYH phytanoyl-CoA 2-hydroxylase
PLN phospholamban
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PSEN1 presenilin 1
PSEN2 presenilin 2
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTEN phosphatase and tensin homolog
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RET ret proto-oncogene
RFC2 replication factor C (activator 1) 2, 40kDa
RPS19 ribosomal protein S19
SCN4A sodium channel, voltage gated, type IV alpha subunit
SCN5A sodium channel, voltage gated, type V alpha subunit
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SMAD4 SMAD family member 4
SNAP29 synaptosomal-associated protein, 29kDa
TAZ tafazzin
TBL2 transducin (beta)-like 2
TF transferrin
TMEM70 transmembrane protein 70
TMPO thymopoietin
TNNI3 troponin I type 3 (cardiac)
TNNT2 troponin T type 2 (cardiac)
TPI1 triosephosphate isomerase 1
TPM1 tropomyosin 1 (alpha)
TRIM37 tripartite motif containing 37
TRNE
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WFS1 Wolfram syndrome 1 (wolframin)
WRN Werner syndrome, RecQ helicase-like