congestive heart failure Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body. (Human Disease Ontology, DOID_6000)
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Genes

567 genes co-occuring with the disease congestive heart failure in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ACE angiotensin I converting enzyme 3.10682
NPPA natriuretic peptide A 2.7788
REN renin 2.30137
NPPB natriuretic peptide B 2.10376
AVP arginine vasopressin 1.74324
MME membrane metallo-endopeptidase 1.70224
EDN1 endothelin 1 1.6936
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 1.68679
DNAH8 dynein, axonemal, heavy chain 8 1.55557
PLN phospholamban 1.54628
ADM adrenomedullin 1.51501
ALB albumin 1.47286
TNF tumor necrosis factor 1.46451
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.46451
KNG1 kininogen 1 1.44738
TNNT2 troponin T type 2 (cardiac) 1.43508
NPPC natriuretic peptide C 1.43464
EDNRA endothelin receptor type A 1.41314
SHF Src homology 2 domain containing F 1.40001
TNNI3 troponin I type 3 (cardiac) 1.35899
CRP C-reactive protein, pentraxin-related 1.34897
NPR1 natriuretic peptide receptor 1 1.32061
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.28435
INS insulin 1.26865
UTS2 urotensin 2 1.26081
GUCY2C guanylate cyclase 2C 1.2382
IL6 interleukin 6 1.23777
ADCY2 adenylate cyclase 2 (brain) 1.21695
AQP2 aquaporin 2 (collecting duct) 1.2031
ADRB1 adrenoceptor beta 1 1.20093
ETV3 ets variant 3 1.16179
CTF1 cardiotrophin 1 1.1173
PLAT plasminogen activator, tissue 1.11309
NPY neuropeptide Y 1.08579
NOS3 nitric oxide synthase 3 (endothelial cell) 1.0795
VMAC vimentin-type intermediate filament associated coiled-coil protein 1.05135
ERBB2 erb-b2 receptor tyrosine kinase 2 1.03704
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 1.02608
CASQ2 calsequestrin 2 (cardiac muscle) 1.02608
PDE5A phosphodiesterase 5A, cGMP-specific 1.0071
MGAM maltase-glucoamylase 0.994439
EFS embryonal Fyn-associated substrate 0.99233
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 0.97254
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 0.950769
ADRB2 adrenoceptor beta 2, surface 0.949936
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.927105
IGF1 insulin-like growth factor 1 (somatomedin C) 0.924626
SPATA5 spermatogenesis associated 5 0.918436
RYR2 ryanodine receptor 2 (cardiac) 0.908965
TTR transthyretin 0.904032
AMPD1 adenosine monophosphate deaminase 1 0.901978
MMP2 matrix metallopeptidase 2 0.882701
SOD2 superoxide dismutase 2, mitochondrial 0.844211
FBXL20 F-box and leucine-rich repeat protein 20 0.840525
PDE3A phosphodiesterase 3A, cGMP-inhibited 0.831099
GJA1 gap junction protein, alpha 1, 43kDa 0.819616
AGTR1 angiotensin II receptor, type 1 0.812232
UTS2R urotensin 2 receptor 0.80977
CYTIP cytohesin 1 interacting protein 0.806077
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.802795
NANP N-acetylneuraminic acid phosphatase 0.782298
TGFB1 transforming growth factor, beta 1 0.78066
TRIP12 thyroid hormone receptor interactor 12 0.780251
MLX MLX, MAX dimerization protein 0.777795
NPR3 natriuretic peptide receptor 3 0.765127
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.75005
TIMP1 TIMP metallopeptidase inhibitor 1 0.745172
CMA1 chymase 1, mast cell 0.741517
MMP9 matrix metallopeptidase 9 0.741111
ACOT2 acyl-CoA thioesterase 2 0.740299
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.739082
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.730976
AVPR2 arginine vasopressin receptor 2 0.727738
CDK5RAP1 CDK5 regulatory subunit associated protein 1 0.726929
PTH parathyroid hormone 0.724907
MMP1 matrix metallopeptidase 1 0.72329
CALCA calcitonin-related polypeptide alpha 0.722482
TTN titin 0.704742
POMC proopiomelanocortin 0.70434
YME1L1 YME1-like 1 ATPase 0.703134
VWF von Willebrand factor 0.700722
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 0.699919
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.6939
AMH anti-Mullerian hormone 0.693499
ATL3 atlastin GTPase 3 0.692697
F2 coagulation factor II (thrombin) 0.681894
POPDC2 popeye domain containing 2 0.676308
PPARG peroxisome proliferator-activated receptor gamma 0.675909
MGP matrix Gla protein 0.674713
IL1B interleukin 1, beta 0.66596
MB myoglobin 0.665166
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.653276
ADCY6 adenylate cyclase 6 0.644586
AOC3 amine oxidase, copper containing 3 0.644192
EGFR epidermal growth factor receptor 0.639463
AQP6 aquaporin 6, kidney specific 0.638676
GPX5 glutathione peroxidase 5 0.635528
GPX4 glutathione peroxidase 4 0.632384
ECE1 endothelin converting enzyme 1 0.627672
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.619442
CORIN corin, serine peptidase 0.619051
FBXO32 F-box protein 32 0.617877
GPX1 glutathione peroxidase 1 0.616312
GCG glucagon 0.611229
PLG plasminogen 0.609276
FBN1 fibrillin 1 0.606152
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.604981
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 0.60225
GJC1 gap junction protein, gamma 1, 45kDa 0.60186
TIMP4 TIMP metallopeptidase inhibitor 4 0.594454
UCN2 urocortin 2 0.581996
MYBPC3 myosin binding protein C, cardiac 0.578494
YIPF1 Yip1 domain family, member 1 0.575383
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.568775
PPARA peroxisome proliferator-activated receptor alpha 0.568386
LDHAL6B lactate dehydrogenase A-like 6B 0.56722
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 0.561781
PRKG1 protein kinase, cGMP-dependent, type I 0.55945
CAT catalase 0.55945
DMD dystrophin 0.557897
IGLV2-8 immunoglobulin lambda variable 2-8 0.556344
EPO erythropoietin 0.556344
LEP leptin 0.554791
CST3 cystatin C 0.545481
AOC2 amine oxidase, copper containing 2 (retina-specific) 0.544705
LDHA lactate dehydrogenase A 0.540829
AAAS achalasia, adrenocortical insufficiency, alacrimia 0.540442
UCN urocortin 0.535796
BBS2 Bardet-Biedl syndrome 2 0.534635
F3 coagulation factor III (thromboplastin, tissue factor) 0.534248
AQP7 aquaporin 7 0.533088
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.526132
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.524974
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 0.51919
ERAS ES cell expressed Ras 0.518034
NUP85 nucleoporin 85kDa 0.513417
LDHAL6A lactate dehydrogenase A-like 6A 0.508424
GHRL ghrelin/obestatin prepropeptide 0.507657
TF transferrin 0.507273
RLN1 relaxin 1 0.503441
MYH7 myosin, heavy chain 7, cardiac muscle, beta 0.500761
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 0.498085
RYR1 ryanodine receptor 1 (skeletal) 0.496175
ADRBK1 adrenergic, beta, receptor kinase 1 0.495029
RAMP2 receptor (G protein-coupled) activity modifying protein 2 0.488549
VASP vasodilator-stimulated phosphoprotein 0.486646
IL10 interleukin 10 0.480945
LDHC lactate dehydrogenase C 0.478668
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.477909
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.474877
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.474498
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.472225
PAPLN papilin, proteoglycan-like sulfated glycoprotein 0.471846
POPDC3 popeye domain containing 3 0.470332
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.469197
EPHA4 EPH receptor A4 0.468819
F8 coagulation factor VIII, procoagulant component 0.468819
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 0.463149
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.460883
OR13C4 olfactory receptor, family 13, subfamily C, member 4 0.460506
ADORA1 adenosine A1 receptor 0.457864
IL1RN interleukin 1 receptor antagonist 0.454847
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4 0.451831
RBMS2 RNA binding motif, single stranded interacting protein 2 0.451078
KMT2A lysine (K)-specific methyltransferase 2A 0.448064
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.440538
CS citrate synthase 0.438658
GJA5 gap junction protein, alpha 5, 40kDa 0.438658
CD34 CD34 molecule 0.438282
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.43753
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.434899
PDE3B phosphodiesterase 3B, cGMP-inhibited 0.434899
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 0.434524
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.432646
CCDC27 coiled-coil domain containing 27 0.428891
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.427015
IGLV3-9 immunoglobulin lambda variable 3-9 (gene/pseudogene) 0.426265
ATP11A ATPase, class VI, type 11A 0.425514
UCN3 urocortin 3 0.424765
NPTXR neuronal pentraxin receptor 0.42139
ACVRL1 activin A receptor type II-like 1 0.418394
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 0.413527
ACE2 angiotensin I converting enzyme 2 0.412405
LCN2 lipocalin 2 0.411657
VKORC1 vitamin K epoxide reductase complex, subunit 1 0.410161
CCL2 chemokine (C-C motif) ligand 2 0.40904
SLIT2 slit homolog 2 (Drosophila) 0.407545
THBD thrombomodulin 0.407545
REM2 RAS (RAD and GEM)-like GTP binding 2 0.406051
MANEAL mannosidase, endo-alpha-like 0.405305
CKM creatine kinase, muscle 0.404557
CYGB cytoglobin 0.404184
CPSF3L cleavage and polyadenylation specific factor 3-like 0.403438
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.402318
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.401945
RNASEH2A ribonuclease H2, subunit A 0.396725
JUN jun proto-oncogene 0.395608
ALPPL2 alkaline phosphatase, placental-like 2 0.391141
ALPP alkaline phosphatase, placental 0.390397
ALPL alkaline phosphatase, liver/bone/kidney 0.390025
PRB3 proline-rich protein BstNI subfamily 3 0.386679
EDNRB endothelin receptor type B 0.386308
PITX1 paired-like homeodomain 1 0.384822
TRDN triadin 0.382223
ACTC1 actin, alpha, cardiac muscle 1 0.381852
CTGF connective tissue growth factor 0.374068
C16ORF82 chromosome 16 open reading frame 82 0.372587
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 0.370368
TH tyrosine hydroxylase 0.368888
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 0.368888
LDHB lactate dehydrogenase B 0.368518
AQP3 aquaporin 3 (Gill blood group) 0.368149
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.366671
TAC1 tachykinin, precursor 1 0.36187
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 0.359289
CXCL8 chemokine (C-X-C motif) ligand 8 0.356341
DSC3 desmocollin 3 0.349349
PRRC2A proline-rich coiled-coil 2A 0.349349
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 0.346042
FN1 fibronectin 1 0.345308
SELE selectin E 0.343473
OR4F29 olfactory receptor, family 4, subfamily F, member 29 0.343473
PPAN-P2RY11 PPAN-P2RY11 readthrough 0.343106
P2RY11 purinergic receptor P2Y, G-protein coupled, 11 0.343106
DPP4 dipeptidyl-peptidase 4 0.340539
TIMP2 TIMP metallopeptidase inhibitor 2 0.339806
BAX BCL2-associated X protein 0.33944
OR10R2 olfactory receptor, family 10, subfamily R, member 2 0.33651
KIAA0101 KIAA0101 0.336144
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.335778
FCF1 FCF1 rRNA-processing protein 0.333218
PLD2 phospholipase D2 0.331391
PHOX2B paired-like homeobox 2b 0.331025
CREM cAMP responsive element modulator 0.3292
LARS leucyl-tRNA synthetase 0.3292
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.328834
TPM1 tropomyosin 1 (alpha) 0.321545
G6PC3 glucose 6 phosphatase, catalytic, 3 0.32009
TOP1MT topoisomerase (DNA) I, mitochondrial 0.318999
NOTCH1 notch 1 0.316092
CD4 CD4 molecule 0.315729
FABP3 fatty acid binding protein 3, muscle and heart 0.315729
FGD1 FYVE, RhoGEF and PH domain containing 1 0.313915
FTH1 ferritin, heavy polypeptide 1 0.313915
FTL ferritin, light polypeptide 0.313915
ICAM1 intercellular adhesion molecule 1 0.312464
MMP3 matrix metallopeptidase 3 0.309928
CCNA2 cyclin A2 0.308842
HBA2 hemoglobin, alpha 2 0.30848
GATA4 GATA binding protein 4 0.308118
NPS neuropeptide S 0.304503
BTNL9 butyrophilin-like 9 0.301976
PPARD peroxisome proliferator-activated receptor delta 0.301615
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.299812
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 0.299092
VCAM1 vascular cell adhesion molecule 1 0.297651
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.297291
AQP1 aquaporin 1 (Colton blood group) 0.292616
CSF3 colony stimulating factor 3 (granulocyte) 0.292257
DSCR4 Down syndrome critical region 4 0.290821
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.290462
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.287235
MDH1 malate dehydrogenase 1, NAD (soluble) 0.285444
PDK4 pyruvate dehydrogenase kinase, isozyme 4 0.282582
UQCRH ubiquinol-cytochrome c reductase hinge protein 0.272597
TPTE transmembrane phosphatase with tensin homology 0.267267
MURC muscle-related coiled-coil protein 0.265849
IL2 interleukin 2 0.260184
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.25877
CD79A CD79a molecule, immunoglobulin-associated alpha 0.256299
TXN thioredoxin 0.256299
PI16 peptidase inhibitor 16 0.254536
DCT dopachrome tautomerase 0.254183
BMP8B bone morphogenetic protein 8b 0.252422
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.25207
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.251366
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.250663
CALCRL calcitonin receptor-like 0.250311
ZFPM2 zinc finger protein, FOG family member 2 0.24996
B2M beta-2-microglobulin 0.248905
CRHR2 corticotropin releasing hormone receptor 2 0.248554
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 0.248203
BMP2K BMP2 inducible kinase 0.248203
RIPK4 receptor-interacting serine-threonine kinase 4 0.246098
CCL3 chemokine (C-C motif) ligand 3 0.245046
UTS2B urotensin 2B 0.243295
HAVCR1 hepatitis A virus cellular receptor 1 0.243295
CDK11A cyclin-dependent kinase 11A 0.242595
FBLIM1 filamin binding LIM protein 1 0.238752
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 0.237357
SMAD2 SMAD family member 2 0.23492
OBSL1 obscurin-like 1 0.23492
MSTN myostatin 0.234225
DUOX1 dual oxidase 1 0.232489
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.232489
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 0.230409
CYP2D7 cytochrome P450, family 2, subfamily D, polypeptide 7 (gene/pseudogene) 0.230063
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 0.226262
ACOT7 acyl-CoA thioesterase 7 0.223509
RPL13A ribosomal protein L13a 0.223165
RAMP3 receptor (G protein-coupled) activity modifying protein 3 0.223165
LOX lysyl oxidase 0.220766
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 0.220766
PIDD1 p53-induced death domain protein 1 0.220424
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.220424
LOXL3 lysyl oxidase-like 3 0.215653
BVES blood vessel epicardial substance 0.215314
DUOX2 dual oxidase 2 0.213959
CYB5R4 cytochrome b5 reductase 4 0.213621
ADA adenosine deaminase 0.212608
CFH complement factor H 0.212271
UBAP1 ubiquitin associated protein 1 0.211261
IGFBP3 insulin-like growth factor binding protein 3 0.210253
SAMD4B sterile alpha motif domain containing 4B 0.209583
DSE dermatan sulfate epimerase 0.209248
XPR1 xenotropic and polytropic retrovirus receptor 1 0.207912
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 0.206913
VCL vinculin 0.20658
IL18 interleukin 18 0.204923
CLTC clathrin, heavy chain (Hc) 0.203275
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.201962
NOX4 NADPH oxidase 4 0.200006
SHD Src homology 2 domain containing transforming protein D 0.200006
HMOX1 heme oxygenase 1 0.199356
CYB5RL cytochrome b5 reductase-like 0.199033
MYLK myosin light chain kinase 0.198064
GPR182 G protein-coupled receptor 182 0.198064
PF4 platelet factor 4 0.197099
ACO2 aconitase 2, mitochondrial 0.196779
CD151 CD151 molecule (Raph blood group) 0.196139
CYB5R1 cytochrome b5 reductase 1 0.19582
PDZK1IP1 PDZK1 interacting protein 1 0.19578
PPIF peptidylprolyl isomerase F 0.195501
ERF Ets2 repressor factor 0.195501
RXFP4 relaxin/insulin-like family peptide receptor 4 0.194548
NME2 NME/NM23 nucleoside diphosphate kinase 2 0.192031
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 0.191719
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 0.191719
CAV1 caveolin 1, caveolae protein, 22kDa 0.191408
AGXT2 alanine--glyoxylate aminotransferase 2 0.189859
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 0.189551
FOS FBJ murine osteosarcoma viral oncogene homolog 0.188022
IGLV1-36 immunoglobulin lambda variable 1-36 0.187719
MEGF6 multiple EGF-like-domains 6 0.187719
DAND5 DAN domain family member 5, BMP antagonist 0.187719
MYBPC2 myosin binding protein C, fast type 0.18651
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.185612
AIRE autoimmune regulator 0.185016
PCP2 Purkinje cell protein 2 0.184424
CA5B carbonic anhydrase VB, mitochondrial 0.184424
AATF apoptosis antagonizing transcription factor 0.184128
TAOK1 TAO kinase 1 0.183835
CYB5R2 cytochrome b5 reductase 2 0.183541
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 0.182666
OPN3 opsin 3 0.18151
AQP8 aquaporin 8 0.180937
CRYAB crystallin, alpha B 0.180652
OR10K1 olfactory receptor, family 10, subfamily K, member 1 0.180367
METTL13 methyltransferase like 13 0.17952
FGF23 fibroblast growth factor 23 0.17952
NOS2 nitric oxide synthase 2, inducible 0.179239
ZBTB48 zinc finger and BTB domain containing 48 0.178403
CD63 CD63 molecule 0.177301
LCK LCK proto-oncogene, Src family tyrosine kinase 0.175411
TRIM37 tripartite motif containing 37 0.175146
MYBPC1 myosin binding protein C, slow type 0.175146
HAMP hepcidin antimicrobial peptide 0.175146
TBCD tubulin folding cofactor D 0.174881
LINS lines homolog (Drosophila) 0.174617
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 0.174354
TMC6 transmembrane channel-like 6 0.173314
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.173057
VEGFA vascular endothelial growth factor A 0.172038
ADRA2C adrenoceptor alpha 2C 0.171036
KLF6 Kruppel-like factor 6 0.170544
GDF1 growth differentiation factor 1 0.169812
HBA1 hemoglobin, alpha 1 0.169091
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.168381
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 0.168381
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 0.168148
PNPLA2 patatin-like phospholipase domain containing 2 0.167452
CPB1 carboxypeptidase B1 (tissue) 0.167224
F9 coagulation factor IX 0.167224
MED13L mediator complex subunit 13-like 0.166768
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 0.166319
GPANK1 G patch domain and ankyrin repeats 1 0.166095
RXFP3 relaxin/insulin-like family peptide receptor 3 0.165435
GDF11 growth differentiation factor 11 0.165435
CAPN2 calpain 2, (m/II) large subunit 0.164571
BMP4 bone morphogenetic protein 4 0.163729
GDF15 growth differentiation factor 15 0.162505
RGS6 regulator of G-protein signaling 6 0.162306
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.161523
RETN resistin 0.161331
PER1 period circadian clock 1 0.15948
IRX4 iroquois homeobox 4 0.158951
MAPT microtubule-associated protein tau 0.158778
CKB creatine kinase, brain 0.158266
S100A5 S100 calcium binding protein A5 0.157929
SMAD6 SMAD family member 6 0.151068
EXOC2 exocyst complex component 2 0.147467
IPO7 importin 7 0.147227
BMP2 bone morphogenetic protein 2 0.146476
RCN1 reticulocalbin 1, EF-hand calcium binding domain 0.146445
CKAP4 cytoskeleton-associated protein 4 0.146191
HOXB2 homeobox B2 0.145744
MAP2K5 mitogen-activated protein kinase kinase 5 0.145659
HOXB6 homeobox B6 0.145659
GRP gastrin-releasing peptide 0.145137
PDE9A phosphodiesterase 9A 0.144587
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.144501
NCR3 natural cytotoxicity triggering receptor 3 0.14435
RTN4 reticulon 4 0.144223
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 0.143784
OSTM1 osteopetrosis associated transmembrane protein 1 0.143698
CAST calpastatin 0.143595
TRPC6 transient receptor potential cation channel, subfamily C, member 6 0.143521
FNDC3A fibronectin type III domain containing 3A 0.143196
HOXA5 homeobox A5 0.142975
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.142885
TGFBR3 transforming growth factor, beta receptor III 0.142883
CAMP cathelicidin antimicrobial peptide 0.142846
BMP1 bone morphogenetic protein 1 0.142733
HMGB2 high mobility group box 2 0.142686
ACTA2 actin, alpha 2, smooth muscle, aorta 0.142606
SMAD4 SMAD family member 4 0.142592
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 0.142555
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.142525
CLCN7 chloride channel, voltage-sensitive 7 0.142481
LHB luteinizing hormone beta polypeptide 0.142403
GRAP2 GRB2-related adaptor protein 2 0.142397
ACVR2A activin A receptor, type IIA 0.142393
HOXB7 homeobox B7 0.14237
LIMK1 LIM domain kinase 1 0.142324
CYCS cytochrome c, somatic 0.142296
RFC2 replication factor C (activator 1) 2, 40kDa 0.142118
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.142091
BMP7 bone morphogenetic protein 7 0.141874
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 0.141764
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 0.141656
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.141586
ACVR1 activin A receptor, type I 0.141547
PDLIM1 PDZ and LIM domain 1 0.141457
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.141346
DYNLT1 dynein, light chain, Tctex-type 1 0.141061
CFL1 cofilin 1 (non-muscle) 0.141046
PDGFA platelet-derived growth factor alpha polypeptide 0.140948
FLNB filamin B, beta 0.140795
MAOA monoamine oxidase A 0.140791
GZMM granzyme M (lymphocyte met-ase 1) 0.140584
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.140428
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.140151
HMGA2 high mobility group AT-hook 2 0.140094
CENPB centromere protein B, 80kDa 0.14008
PROS1 protein S (alpha) 0.139933
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 0.139794
KAT8 K(lysine) acetyltransferase 8 0.138766
INTU inturned planar cell polarity protein 0.135764
FKBP1A FK506 binding protein 1A, 12kDa 0.134135
MADD MAP-kinase activating death domain 0.133686
ALOX5 arachidonate 5-lipoxygenase 0.133544
SPINK5 serine peptidase inhibitor, Kazal type 5 0.13313
PTGIS prostaglandin I2 (prostacyclin) synthase 0.132766
CYBRD1 cytochrome b reductase 1 0.132707
GDF5 growth differentiation factor 5 0.132628
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.132428
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 0.132316
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 0.132306
RPSA ribosomal protein SA 0.131963
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.131652
NDP Norrie disease (pseudoglioma) 0.131475
HTRA2 HtrA serine peptidase 2 0.131262
HLA-C major histocompatibility complex, class I, C 0.131159
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 0.131091
STAT5A signal transducer and activator of transcription 5A 0.130141
LBR lamin B receptor 0.130129
EPHX2 epoxide hydrolase 2, cytoplasmic 0.129914
RPAP3 RNA polymerase II associated protein 3 0.129694
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 0.129576
PVALB parvalbumin 0.129443
APEH acylaminoacyl-peptide hydrolase 0.12939
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 0.129201
LPCAT2 lysophosphatidylcholine acyltransferase 2 0.128814
FSTL1 follistatin-like 1 0.128488
STAT5B signal transducer and activator of transcription 5B 0.12843
WASH7P WAS protein family homolog 7 pseudogene 0.128386
BMP6 bone morphogenetic protein 6 0.128283
WASH1 WAS protein family homolog 1 0.128239
WASH6P WAS protein family homolog 6 pseudogene 0.128136
NONO non-POU domain containing, octamer-binding 0.128033
VIP vasoactive intestinal peptide 0.127342
IRF7 interferon regulatory factor 7 0.126974
MPG N-methylpurine-DNA glycosylase 0.126698
THBS4 thrombospondin 4 0.126038
CYBA cytochrome b-245, alpha polypeptide 0.12513
KLHL17 kelch-like family member 17 0.124436
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) 0.123692
NRG1 neuregulin 1 0.122203
MEA1 male-enhanced antigen 1 0.12216
MIR22 microRNA 22 0.121874
LGALS3 lectin, galactoside-binding, soluble, 3 0.121716
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 0.121311
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 0.121241
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.121125
FHL2 four and a half LIM domains 2 0.120563
FBN2 fibrillin 2 0.118383
PC pyruvate carboxylase 0.117798
SLC52A3 solute carrier family 52 (riboflavin transporter), member 3 0.117415
MPO myeloperoxidase 0.117169
SFTPC surfactant protein C 0.115741
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 0.113734
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.113734
FOXF1 forkhead box F1 0.113543
SOX18 SRY (sex determining region Y)-box 18 0.113095
SEPN1 selenoprotein N, 1 0.112999
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 0.112739
IRF3 interferon regulatory factor 3 0.112673
TBK1 TANK-binding kinase 1 0.112673
SIM2 single-minded family bHLH transcription factor 2 0.112409
HSPA1B heat shock 70kDa protein 1B 0.112409
ROCK1P1 Rho-associated, coiled-coil containing protein kinase 1 pseudogene 1 0.11171
RHOA ras homolog family member A 0.111676
ITGB8 integrin, beta 8 0.111235
VEGFB vascular endothelial growth factor B 0.1111
GPER1 G protein-coupled estrogen receptor 1 0.111066
MMP8 matrix metallopeptidase 8 0.110577
THEM5 thioesterase superfamily member 5 0.110333
SMOX spermine oxidase 0.110089
CYB5R3 cytochrome b5 reductase 3 0.109371
TPM3 tropomyosin 3 0.109371
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 0.109227
ITGB6 integrin, beta 6 0.108862
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.108419
MMP7 matrix metallopeptidase 7 0.108198
SFTPA1 surfactant protein A1 0.10805
ITGB7 integrin, beta 7 0.107822
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 0.107822
ATG7 autophagy related 7 0.107671
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.107481
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 0.107215
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.107064
MTSS1 metastasis suppressor 1 0.107026
CYR61 cysteine-rich, angiogenic inducer, 61 0.106676
FOXO3 forkhead box O3 0.104653
CYS1 cystin 1 0.104325
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 0.104078
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 0.10266
EGLN3 egl-9 family hypoxia-inducible factor 3 0.101673
PAOX polyamine oxidase (exo-N4-amino) 0.101673
HBG2 hemoglobin, gamma G 0.101242
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 0.101242
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 0.100889
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.100668
ISG20 interferon stimulated exonuclease gene 20kDa 0.100183
F5 coagulation factor V (proaccelerin, labile factor) 0.099871
CHKA choline kinase alpha 0.099735
MMP10 matrix metallopeptidase 10 0.098465
TICAM2 toll-like receptor adaptor molecule 2 0.097356
ATG5 autophagy related 5 0.097262
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.096791
HLA-DMA major histocompatibility complex, class II, DM alpha 0.096744
STAB2 stabilin 2 0.096697
ADIPOR2 adiponectin receptor 2 0.096179
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.096083
SCARB2 scavenger receptor class B, member 2 0.095506
GYPE glycophorin E (MNS blood group) 0.095362
GCDH glutaryl-CoA dehydrogenase 0.095314