conessine-4777 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the conessine-4777 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACSF2 acyl-CoA synthetase family member 2
ACSL4 acyl-CoA synthetase long-chain family member 4
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
AHNAK2 AHNAK nucleoprotein 2
ALOX15 arachidonate 15-lipoxygenase
ALS2CL ALS2 C-terminal like
AMPD3 adenosine monophosphate deaminase 3
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
ARMC4 armadillo repeat containing 4
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BEGAIN brain-enriched guanylate kinase-associated
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CALCA calcitonin-related polypeptide alpha
CAMK4 calcium/calmodulin-dependent protein kinase IV
CARD9 caspase recruitment domain family, member 9
CCL19 chemokine (C-C motif) ligand 19
CDK17 cyclin-dependent kinase 17
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
COPZ2 coatomer protein complex, subunit zeta 2
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRMP1 collapsin response mediator protein 1
DDIT3 DNA-damage-inducible transcript 3
DENND4A DENN/MADD domain containing 4A
DMBT1 deleted in malignant brain tumors 1
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
EFNA3 ephrin-A3
EPHA1 EPH receptor A1
EPOR erythropoietin receptor
FER fer (fps/fes related) tyrosine kinase
FHL1 four and a half LIM domains 1
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GDF5 growth differentiation factor 5
GHRHR growth hormone releasing hormone receptor
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GPER1 G protein-coupled estrogen receptor 1
GPNMB glycoprotein (transmembrane) nmb
GPR153 G protein-coupled receptor 153
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
HDAC5 histone deacetylase 5
HOXA10 homeobox A10
HOXA4 homeobox A4
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFT27 intraflagellar transport 27
IGF1R insulin-like growth factor 1 receptor
IL6ST interleukin 6 signal transducer
IRF4 interferon regulatory factor 4
KDM4B lysine (K)-specific demethylase 4B
LAMC2 laminin, gamma 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIMK2 LIM domain kinase 2
LPCAT3 lysophosphatidylcholine acyltransferase 3
MAGEA12 melanoma antigen family A12
NCOA2 nuclear receptor coactivator 2
NXPE3 neurexophilin and PC-esterase domain family, member 3
PARP11 poly (ADP-ribose) polymerase family, member 11
PDC phosducin
PDE3B phosphodiesterase 3B, cGMP-inhibited
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PML promyelocytic leukemia
PRM1 protamine 1
PRSS3 protease, serine, 3
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RBMS2 RNA binding motif, single stranded interacting protein 2
S100A8 S100 calcium binding protein A8
SERGEF secretion regulating guanine nucleotide exchange factor
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIGLEC9 sialic acid binding Ig-like lectin 9
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SMAD5 SMAD family member 5
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SRF serum response factor (c-fos serum response element-binding transcription factor)
SRSF1 serine/arginine-rich splicing factor 1
STS steroid sulfatase (microsomal), isozyme S
SUGP1 SURP and G patch domain containing 1
SYNGR1 synaptogyrin 1
SYT11 synaptotagmin XI
TBL1Y transducin (beta)-like 1, Y-linked
TBX5 T-box 5
TCF4 transcription factor 4
TCP10 t-complex 10
TCP11L1 t-complex 11, testis-specific-like 1
TGFBR3 transforming growth factor, beta receptor III
TGM2 transglutaminase 2
TMEM242 transmembrane protein 242
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TRIM2 tripartite motif containing 2
TTC12 tetratricopeptide repeat domain 12
VIPR1 vasoactive intestinal peptide receptor 1
WDR59 WD repeat domain 59
WNT16 wingless-type MMTV integration site family, member 16
XCL1 chemokine (C motif) ligand 1
ZNF675 zinc finger protein 675

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ACAD8 acyl-CoA dehydrogenase family, member 8
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADAP2 ArfGAP with dual PH domains 2
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ARMC7 armadillo repeat containing 7
C16ORF62 chromosome 16 open reading frame 62
CA11 carbonic anhydrase XI
CCNJ cyclin J
CDH3 cadherin 3, type 1, P-cadherin (placental)
CORT cortistatin
DDA1 DET1 and DDB1 associated 1
DEPDC1 DEP domain containing 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF5A2 eukaryotic translation initiation factor 5A2
EMD emerin
ERN2 endoplasmic reticulum to nucleus signaling 2
ERO1L ERO1-like (S. cerevisiae)
FAM173A family with sequence similarity 173, member A
FGF23 fibroblast growth factor 23
FKTN fukutin
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GLI3 GLI family zinc finger 3
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
H1F0 H1 histone family, member 0
HIST1H2AI histone cluster 1, H2ai
HIST1H2BI histone cluster 1, H2bi
HIST1H4C histone cluster 1, H4c
HSPA1L heat shock 70kDa protein 1-like
HYAL2 hyaluronoglucosaminidase 2
IFI6 interferon, alpha-inducible protein 6
IL15RA interleukin 15 receptor, alpha
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KIAA0125 KIAA0125
KIAA0355 KIAA0355
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
MANBA mannosidase, beta A, lysosomal
MAST3 microtubule associated serine/threonine kinase 3
METTL2B methyltransferase like 2B
METTL8 methyltransferase like 8
MFAP2 microfibrillar-associated protein 2
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MGC12488
MON1B MON1 secretory trafficking family member B
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MRPL41 mitochondrial ribosomal protein L41
MSANTD2 Myb/SANT-like DNA-binding domain containing 2
MTERF4 mitochondrial transcription termination factor 4
NDRG1 N-myc downstream regulated 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OTUD3 OTU deubiquitinase 3
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PDGFRL platelet-derived growth factor receptor-like
PGPEP1 pyroglutamyl-peptidase I
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PTTG1IP pituitary tumor-transforming 1 interacting protein
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAD9A RAD9 homolog A (S. pombe)
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
SASH1 SAM and SH3 domain containing 1
SAYSD1 SAYSVFN motif domain containing 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SETD8 SET domain containing (lysine methyltransferase) 8
SGK1 serum/glucocorticoid regulated kinase 1
SHCBP1 SHC SH2-domain binding protein 1
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC46A3 solute carrier family 46, member 3
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TAOK1 TAO kinase 1
TCTN2 tectonic family member 2
TDRD7 tudor domain containing 7
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMEM39B transmembrane protein 39B
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TRABD TraB domain containing
TRIM5 tripartite motif containing 5
TTBK2 tau tubulin kinase 2
TTLL1 tubulin tyrosine ligase-like family member 1
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
ZBTB48 zinc finger and BTB domain containing 48
ZNF211 zinc finger protein 211
ZNF254 zinc finger protein 254
ZNF324 zinc finger protein 324
ZNF428 zinc finger protein 428
ZNF432 zinc finger protein 432
ZNF665 zinc finger protein 665
ZNF747 zinc finger protein 747
ZNF767P zinc finger family member 767, pseudogene
ZNF862 zinc finger protein 862