conessine-4191 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

190 genes differentially expressed following the conessine-4191 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ACSL5 acyl-CoA synthetase long-chain family member 5
ADGRE3 adhesion G protein-coupled receptor E3
ADRA1A adrenoceptor alpha 1A
ALOXE3 arachidonate lipoxygenase 3
ALPI alkaline phosphatase, intestinal
APC adenomatous polyposis coli
APOD apolipoprotein D
AURKC aurora kinase C
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
C1S complement component 1, s subcomponent
CCDC70 coiled-coil domain containing 70
CCDC71 coiled-coil domain containing 71
CCDC85B coiled-coil domain containing 85B
CCKAR cholecystokinin A receptor
CDC14B cell division cycle 14B
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLCN6 chloride channel, voltage-sensitive 6
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COL4A6 collagen, type IV, alpha 6
COL6A1 collagen, type VI, alpha 1
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CREB3L1 cAMP responsive element binding protein 3-like 1
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
DAAM2 dishevelled associated activator of morphogenesis 2
DAPK2 death-associated protein kinase 2
DEPDC5 DEP domain containing 5
EDA ectodysplasin A
EGF epidermal growth factor
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGL1 fibrinogen-like 1
FMOD fibromodulin
GFRA2 GDNF family receptor alpha 2
GPSM3 G-protein signaling modulator 3
GUSBP3 glucuronidase, beta pseudogene 3
HEATR6 HEAT repeat containing 6
HMG20B high mobility group 20B
HRH2 histamine receptor H2
HYAL1 hyaluronoglucosaminidase 1
IBSP integrin-binding sialoprotein
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL2 interleukin 2
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INPP5J inositol polyphosphate-5-phosphatase J
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KIF21B kinesin family member 21B
KLF12 Kruppel-like factor 12
KLHL35 kelch-like family member 35
LINC00260 long intergenic non-protein coding RNA 260
LSAMP limbic system-associated membrane protein
LYRM9 LYR motif containing 9
MAP2K7 mitogen-activated protein kinase kinase 7
MEF2D myocyte enhancer factor 2D
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NCALD neurocalcin delta
NLGN4X neuroligin 4, X-linked
NPC1 Niemann-Pick disease, type C1
NTNG1 netrin G1
PCP4 Purkinje cell protein 4
PGPEP1 pyroglutamyl-peptidase I
PLK4 polo-like kinase 4
PLVAP plasmalemma vesicle associated protein
PLXDC1 plexin domain containing 1
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
RAB36 RAB36, member RAS oncogene family
RARB retinoic acid receptor, beta
RHBG Rh family, B glycoprotein (gene/pseudogene)
RIC3 RIC3 acetylcholine receptor chaperone
RPL3L ribosomal protein L3-like
RUNX1 runt-related transcription factor 1
SATB2 SATB homeobox 2
SIDT2 SID1 transmembrane family, member 2
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SOX5 SRY (sex determining region Y)-box 5
SRPK3 SRSF protein kinase 3
SRPX2 sushi-repeat containing protein, X-linked 2
STK24 serine/threonine kinase 24
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TDRD1 tudor domain containing 1
TM6SF2 transmembrane 6 superfamily member 2
TNIK TRAF2 and NCK interacting kinase
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
WISP3 WNT1 inducible signaling pathway protein 3
WNK1 WNK lysine deficient protein kinase 1
WNT3 wingless-type MMTV integration site family, member 3
WNT5B wingless-type MMTV integration site family, member 5B
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF334 zinc finger protein 334
ZNF674 zinc finger protein 674

decreased expression

Symbol Name
ACSBG2 acyl-CoA synthetase bubblegum family member 2
AGBL3 ATP/GTP binding protein-like 3
ALS2CL ALS2 C-terminal like
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANKRD36 ankyrin repeat domain 36
ANOS1 anosmin 1
ANXA10 annexin A10
ARHGAP22 Rho GTPase activating protein 22
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
BTF3P11 basic transcription factor 3 pseudogene 11
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C3ORF36 chromosome 3 open reading frame 36
CCNO cyclin O
CES1 carboxylesterase 1
CIDEB cell death-inducing DFFA-like effector b
CLCN5 chloride channel, voltage-sensitive 5
CLTCL1 clathrin, heavy chain-like 1
CPB1 carboxypeptidase B1 (tissue)
CTAGE9 CTAGE family, member 9
EBF2 early B-cell factor 2
EGFL7 EGF-like-domain, multiple 7
ERCC4 excision repair cross-complementation group 4
FAM118A family with sequence similarity 118, member A
FMO4 flavin containing monooxygenase 4
FRS3 fibroblast growth factor receptor substrate 3
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GALK1 galactokinase 1
GLS2 glutaminase 2 (liver, mitochondrial)
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPX2 glutathione peroxidase 2
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HOOK1 hook microtubule-tethering protein 1
HOXA6 homeobox A6
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
KANSL3 KAT8 regulatory NSL complex subunit 3
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KRT8P12 keratin 8 pseudogene 12
LAX1 lymphocyte transmembrane adaptor 1
LENEP lens epithelial protein
LMNB1 lamin B1
LY86 lymphocyte antigen 86
MAL mal, T-cell differentiation protein
MANBA mannosidase, beta A, lysosomal
MRAS muscle RAS oncogene homolog
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MYO15A myosin XVA
NOTCH4 notch 4
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PALMD palmdelphin
PBOV1 prostate and breast cancer overexpressed 1
PCDHGB5 protocadherin gamma subfamily B, 5
PDE12 phosphodiesterase 12
PLSCR4 phospholipid scramblase 4
POMT2 protein-O-mannosyltransferase 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRB3 proline-rich protein BstNI subfamily 3
PRDM14 PR domain containing 14
PRO2964 uncharacterized protein PRO2964
PROL1 proline rich, lacrimal 1
PRR15L proline rich 15-like
RAB40A RAB40A, member RAS oncogene family
RABL6 RAB, member RAS oncogene family-like 6
RBM12B-AS1 RBM12B antisense RNA 1
RNF126P1 ring finger protein 126 pseudogene 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RUNDC3B RUN domain containing 3B
SFT2D2 SFT2 domain containing 2
SLC12A8 solute carrier family 12, member 8
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLITRK5 SLIT and NTRK-like family, member 5
SP1 Sp1 transcription factor
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TGFBI transforming growth factor, beta-induced, 68kDa
THRAP3 thyroid hormone receptor associated protein 3
TIAM2 T-cell lymphoma invasion and metastasis 2
TIMP4 TIMP metallopeptidase inhibitor 4
TMPRSS4 transmembrane protease, serine 4
TRAF2 TNF receptor-associated factor 2
TSPAN2 tetraspanin 2
TTLL1 tubulin tyrosine ligase-like family member 1
VGF VGF nerve growth factor inducible
ZNF197 zinc finger protein 197
ZNF215 zinc finger protein 215
ZNF253 zinc finger protein 253
ZNF391 zinc finger protein 391
ZNF428 zinc finger protein 428
ZNF528 zinc finger protein 528