colorectal neoplasms Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description uncontrolled cell growth (neoplasia) occurring in the colon, rectum or vermiform appendix. (Experimental Factor Ontology, EFO_0004142)
Similar Terms
Downloads & Tools

Genes

98 genes associated with the disease colorectal neoplasms in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
AHR aryl hydrocarbon receptor
APC adenomatous polyposis coli
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
AR androgen receptor
ARNT aryl hydrocarbon receptor nuclear translocator
ATM ATM serine/threonine kinase
AXIN1 axin 1
BARD1 BRCA1 associated RING domain 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CASP8AP2 caspase 8 associated protein 2
CBS cystathionine-beta-synthase
CCND1 cyclin D1
CCNH cyclin H
CDA cytidine deaminase
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK7 cyclin-dependent kinase 7
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CHEK2 checkpoint kinase 2
COLCA2 colorectal cancer associated 2
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25
DPYS dihydropyrimidinase
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERCC4 excision repair cross-complementation group 4
ERCC5 excision repair cross-complementation group 5
FANCD2 Fanconi anemia, complementation group D2
FANCG Fanconi anemia, complementation group G
FAS Fas cell surface death receptor
GADD45A growth arrest and DNA-damage-inducible, alpha
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GSTP1 glutathione S-transferase pi 1
HRAS Harvey rat sarcoma viral oncogene homolog
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMA5 laminin, alpha 5
LIG1 ligase I, DNA, ATP-dependent
LIG3 ligase III, DNA, ATP-dependent
LIG4 ligase IV, DNA, ATP-dependent
MGMT O-6-methylguanine-DNA methyltransferase
MLH1 mutL homolog 1
MMP1 matrix metallopeptidase 1
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MSH2 mutS homolog 2
MSH3 mutS homolog 3
MSH6 mutS homolog 6
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MUTYH mutY homolog
MYH1 myosin, heavy chain 1, skeletal muscle, adult
MYNN myoneurin
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NBN nibrin
NFE2L2 nuclear factor, erythroid 2-like 2
NQO1 NAD(P)H dehydrogenase, quinone 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NT5E 5'-nucleotidase, ecto (CD73)
OGG1 8-oxoguanine DNA glycosylase
PARP1 poly (ADP-ribose) polymerase 1
PARP4 poly (ADP-ribose) polymerase family, member 4
PCNA proliferating cell nuclear antigen
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
POLB polymerase (DNA directed), beta
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RAD23B RAD23 homolog B (S. cerevisiae)
RAD51 RAD51 recombinase
RAD52 RAD52 homolog (S. cerevisiae)
RAD54B RAD54 homolog B (S. cerevisiae)
RAD9A RAD9 homolog A (S. pombe)
RECQL RecQ helicase-like
RHPN2 rhophilin, Rho GTPase binding protein 2
RPH3AL rabphilin 3A-like (without C2 domains)
SEPP1 selenoprotein P, plasma, 1
SMAD7 SMAD family member 7
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TP53BP2 tumor protein p53 binding protein 2
TP73 tumor protein p73
TYMS thymidylate synthetase
UPB1 ureidopropionase, beta
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
XPA xeroderma pigmentosum, complementation group A
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)