colon adenocarcinoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A colon carcinoma that derives_from epithelial cells of glandular origin. (Human Disease Ontology, DOID_234)
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Genes

316 genes co-occuring with the disease colon adenocarcinoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
KRT20 keratin 20, type I 1.31799
KRT7 keratin 7, type II 1.21738
CDX2 caudal type homeobox 2 1.20223
TYMS thymidylate synthetase 1.12698
HRAS Harvey rat sarcoma viral oncogene homolog 1.05219
TP53 tumor protein p53 1.02187
IL2 interleukin 2 1.01807
KRAS Kirsten rat sarcoma viral oncogene homolog 1.00963
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.988535
SI sucrase-isomaltase (alpha-glucosidase) 0.95996
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2 0.905675
CCDC151 coiled-coil domain containing 151 0.858134
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.833968
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.828639
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 0.808129
CA7 carbonic anhydrase VII 0.804436
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.785165
MSH2 mutS homolog 2 0.777386
MUC2 mucin 2, oligomeric mucus/gel-forming 0.776568
SPACA5 sperm acrosome associated 5 0.765943
ODC1 ornithine decarboxylase 1 0.749644
NTS neurotensin 0.746391
RAB2B RAB2B, member RAS oncogene family 0.741923
DHFR dihydrofolate reductase 0.730571
TGFB1 transforming growth factor, beta 1 0.728547
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.728143
MAP3K7CL MAP3K7 C-terminal like 0.72329
B3GNT7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 0.714005
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.713198
BAX BCL2-associated X protein 0.698313
ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9 0.69751
ABCA10 ATP-binding cassette, sub-family A (ABC1), member 10 0.676706
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6 0.673917
GTDC1 glycosyltransferase-like domain containing 1 0.663181
CCND1 cyclin D1 0.6608
MLH1 mutL homolog 1 0.658422
CYHR1 cysteine/histidine-rich 1 0.650903
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.610448
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 0.610057
DCD dermcidin 0.610057
MCM4 minichromosome maintenance complex component 4 0.604201
LGALS7 lectin, galactoside-binding, soluble, 7 0.60342
RHOT2 ras homolog family member T2 0.59913
SYNE1 spectrin repeat containing, nuclear envelope 1 0.596012
VANGL1 VANGL planar cell polarity protein 1 0.592116
TOP1 topoisomerase (DNA) I 0.589001
BCAP29 B-cell receptor-associated protein 29 0.587054
NDUFAF2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 0.585108
PCNA proliferating cell nuclear antigen 0.571107
TNF tumor necrosis factor 0.565666
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.560616
GAST gastrin 0.544318
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 0.542573
KPTN kaptin (actin binding protein) 0.541605
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.540442
ZDHHC9 zinc finger, DHHC-type containing 9 0.531154
RTN4RL2 reticulon 4 receptor-like 2 0.52536
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 0.522659
ZNF135 zinc finger protein 135 0.521117
PLBD2 phospholipase B domain containing 2 0.501527
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 0.499614
KCTD12 potassium channel tetramerization domain containing 12 0.499231
PCSK9 proprotein convertase subtilisin/kexin type 9 0.498467
CD86 CD86 molecule 0.498085
RRM2B ribonucleotide reductase M2 B (TP53 inducible) 0.495411
LEMD1 LEM domain containing 1 0.491978
NR1I2 nuclear receptor subfamily 1, group I, member 2 0.491597
CALB2 calbindin 2 0.490072
MSH6 mutS homolog 6 0.487027
CPZ carboxypeptidase Z 0.483604
ADAP2 ArfGAP with dual PH domains 2 0.477151
MRPS7 mitochondrial ribosomal protein S7 0.476393
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.474877
PROM1 prominin 1 0.474498
PUF60 poly-U binding splicing factor 60KDa 0.469954
FAM195A family with sequence similarity 195, member A 0.468063
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.466928
GSTA1 glutathione S-transferase alpha 1 0.466172
FURIN furin (paired basic amino acid cleaving enzyme) 0.466172
QTRT1 queuine tRNA-ribosyltransferase 1 0.465038
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.463527
COL13A1 collagen, type XIII, alpha 1 0.459373
UPP1 uridine phosphorylase 1 0.458241
MAP7 microtubule-associated protein 7 0.455601
BTF3 basic transcription factor 3 0.452585
CGN cingulin 0.449571
PCSK6 proprotein convertase subtilisin/kexin type 6 0.443547
CHRDL2 chordin-like 2 0.443171
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.443171
ERBB2 erb-b2 receptor tyrosine kinase 2 0.443171
MLKL mixed lineage kinase domain-like 0.440538
ALDH1B1 aldehyde dehydrogenase 1 family, member B1 0.440162
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.438282
ANXA5 annexin A5 0.437906
SMAD4 SMAD family member 4 0.43753
TPT1 tumor protein, translationally-controlled 1 0.437154
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 0.434524
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B 0.433772
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.43227
CHKA choline kinase alpha 0.43227
DNTT DNA nucleotidylexotransferase 0.431519
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase 0.428516
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) 0.42664
IL11RA interleukin 11 receptor, alpha 0.425139
NAP1L1 nucleosome assembly protein 1-like 1 0.423265
APOLD1 apolipoprotein L domain containing 1 0.415773
TRAPPC10 trafficking protein particle complex 10 0.413901
GSTA2 glutathione S-transferase alpha 2 0.412405
ALPPL2 alkaline phosphatase, placental-like 2 0.405305
ALPP alkaline phosphatase, placental 0.404931
ALPL alkaline phosphatase, liver/bone/kidney 0.404557
KDM3A lysine (K)-specific demethylase 3A 0.402692
CLDN1 claudin 1 0.401572
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 0.398962
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.392629
PNPT1 polyribonucleotide nucleotidyltransferase 1 0.388166
CLDN7 claudin 7 0.388166
FCGBP Fc fragment of IgG binding protein 0.385936
BCL2L1 BCL2-like 1 0.384079
FOS FBJ murine osteosarcoma viral oncogene homolog 0.383337
IGFBP7 insulin-like growth factor binding protein 7 0.380368
VEGFA vascular endothelial growth factor A 0.377773
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 0.377031
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 0.376661
H3F3A H3 histone, family 3A 0.37592
H3F3B H3 histone, family 3B (H3.3B) 0.37592
UGT1A5 UDP glucuronosyltransferase 1 family, polypeptide A5 0.374068
GAL galanin/GMAP prepropeptide 0.372958
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4 0.372217
PDCL2 phosducin-like 2 0.371847
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 0.36741
EGFR epidermal growth factor receptor 0.366301
IFNA1 interferon, alpha 1 0.364824
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.364085
PF4V1 platelet factor 4 variant 1 0.36187
CREB3L4 cAMP responsive element binding protein 3-like 4 0.359289
MCM7 minichromosome maintenance complex component 7 0.35892
MAGEE1 melanoma antigen family E1 0.35892
ALB albumin 0.356709
PLAUR plasminogen activator, urokinase receptor 0.355604
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.354868
GSTA3 glutathione S-transferase alpha 3 0.354131
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase 0.353763
LGALS3 lectin, galactoside-binding, soluble, 3 0.353027
GSTA4 glutathione S-transferase alpha 4 0.351923
SEPW1 selenoprotein W, 1 0.351923
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7 0.351187
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9 0.348981
HEXB hexosaminidase B (beta polypeptide) 0.343473
RGCC regulator of cell cycle 0.343106
CD4 CD4 molecule 0.339073
TMPRSS11D transmembrane protease, serine 11D 0.338707
LYPD3 LY6/PLAUR domain containing 3 0.337975
TSPO translocator protein (18kDa) 0.337975
HOXB9 homeobox B9 0.33651
MTCH2 mitochondrial carrier 2 0.332487
FPGS folylpolyglutamate synthase 0.323002
ELAC2 elaC ribonuclease Z 2 0.321909
CHGA chromogranin A 0.321545
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.318635
SMAD2 SMAD family member 2 0.315729
GUSB glucuronidase, beta 0.309566
HLA-B major histocompatibility complex, class I, B 0.308842
VIP vasoactive intestinal peptide 0.307395
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.303781
CAV2 caveolin 2 0.303059
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.303059
UNG uracil-DNA glycosylase 0.303059
PCCA propionyl CoA carboxylase, alpha polypeptide 0.299452
NQO1 NAD(P)H dehydrogenase, quinone 1 0.299452
POLI polymerase (DNA directed) iota 0.298731
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2 0.297651
SNCG synuclein, gamma (breast cancer-specific protein 1) 0.297291
SELL selectin L 0.294772
RHD Rh blood group, D antigen 0.294413
ARSH arylsulfatase family, member H 0.294053
FN1 fibronectin 1 0.293694
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 0.292975
NHP2 NHP2 ribonucleoprotein 0.290821
M6PR mannose-6-phosphate receptor (cation dependent) 0.290462
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.290462
FASLG Fas ligand (TNF superfamily, member 6) 0.289744
SMAD7 SMAD family member 7 0.288668
CD58 CD58 molecule 0.286877
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.286877
PLS1 plastin 1 0.285802
RAB2A RAB2A, member RAS oncogene family 0.285444
HSPH1 heat shock 105kDa/110kDa protein 1 0.284013
CAT catalase 0.284013
PRDX6 peroxiredoxin 6 0.283655
CCNB1 cyclin B1 0.28294
LECT1 leukocyte cell derived chemotaxin 1 0.280439
CSN1S1 casein alpha s1 0.279724
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.279011
NKX2-1 NK2 homeobox 1 0.278297
GLB1 galactosidase, beta 1 0.276514
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.275801
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.275445
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.275089
ESR2 estrogen receptor 2 (ER beta) 0.273308
CTNND1 catenin (cadherin-associated protein), delta 1 0.273308
TUBB2A tubulin, beta 2A class IIa 0.272597
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 0.27153
DDT D-dopachrome tautomerase 0.269398
CYTL1 cytokine-like 1 0.266558
MAPK8 mitogen-activated protein kinase 8 0.265849
ASCL2 achaete-scute family bHLH transcription factor 2 0.264785
MCM2 minichromosome maintenance complex component 2 0.264077
GRM8 glutamate receptor, metabotropic 8 0.264077
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.263722
HIST1H1B histone cluster 1, H1b 0.259124
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.257005
ACVR2B activin A receptor, type IIB 0.255946
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.252422
RRM2 ribonucleotide reductase M2 0.252422
AHR aryl hydrocarbon receptor 0.25207
MTDH metadherin 0.25207
RIPK3 receptor-interacting serine-threonine kinase 3 0.251718
IL1B interleukin 1, beta 0.251718
PDE3A phosphodiesterase 3A, cGMP-inhibited 0.250663
JUN jun proto-oncogene 0.24996
GLG1 golgi glycoprotein 1 0.249608
ETHE1 ethylmalonic encephalopathy 1 0.249608
FABP6 fatty acid binding protein 6, ileal 0.248554
LALBA lactalbumin, alpha- 0.247501
GSN gelsolin 0.246448
NTSR1 neurotensin receptor 1 (high affinity) 0.245396
TRO trophinin 0.243645
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.242595
SYP synaptophysin 0.242245
TUBB tubulin, beta class I 0.238054
CALCOCO2 calcium binding and coiled-coil domain 2 0.237009
MMP2 matrix metallopeptidase 2 0.23666
DNASE1L3 deoxyribonuclease I-like 3 0.236312
GRPR gastrin-releasing peptide receptor 0.235616
FKBP4 FK506 binding protein 4, 59kDa 0.235268
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 0.234225
C21ORF2 chromosome 21 open reading frame 2 0.232836
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 0.231102
TANK TRAF family member-associated NFKB activator 0.230409
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 0.229716
CES2 carboxylesterase 2 0.228333
TBPL1 TBP-like 1 0.226952
TCN2 transcobalamin II 0.224884
PPP1R9B protein phosphatase 1, regulatory subunit 9B 0.22454
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 0.222822
CCNC cyclin C 0.222822
EPRS glutamyl-prolyl-tRNA synthetase 0.221793
SLC31A1 solute carrier family 31 (copper transporter), member 1 0.22145
JUP junction plakoglobin 0.22145
IGF2 insulin-like growth factor 2 0.220081
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 0.220081
MAN2B1 mannosidase, alpha, class 2B, member 1 0.218374
ADM2 adrenomedullin 2 0.218034
CSE1L CSE1 chromosome segregation 1-like (yeast) 0.217012
AGO1 argonaute RISC catalytic component 1 0.216332
CD44 CD44 molecule (Indian blood group) 0.215992
CDK4 cyclin-dependent kinase 4 0.215653
FLOT2 flotillin 2 0.215314
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 0.214636
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 0.213621
OLFM4 olfactomedin 4 0.213283
MX1 MX dynamin-like GTPase 1 0.212608
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.209583
ANPEP alanyl (membrane) aminopeptidase 0.208245
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.20658
NBPF1 neuroblastoma breakpoint family, member 1 0.206248
MCM6 minichromosome maintenance complex component 6 0.205916
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 0.204263
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.203933
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.198709
FAP fibroblast activation protein, alpha 0.19742
CCM2 cerebral cavernous malformation 2 0.196139
IL17C interleukin 17C 0.19582
CLDN18 claudin 18 0.195501
GRIK4 glutamate receptor, ionotropic, kainate 4 0.1936
HSPA1A heat shock 70kDa protein 1A 0.192971
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 0.192344
FBN2 fibrillin 2 0.191719
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 0.191097
COASY CoA synthase 0.186811
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 0.18591
LOX lysyl oxidase 0.18591
HSPA4 heat shock 70kDa protein 4 0.181222
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 0.179802
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 0.17896
IGF1 insulin-like growth factor 1 (somatomedin C) 0.17896
BMP5 bone morphogenetic protein 5 0.178403
FBXO32 F-box protein 32 0.177851
KDR kinase insert domain receptor 0.177029
HMGA2 high mobility group AT-hook 2 0.176215
GFRA1 GDNF family receptor alpha 1 0.176215
SLCO1C1 solute carrier organic anion transporter family, member 1C1 0.175411
SDF4 stromal cell derived factor 4 0.174354
CDK2 cyclin-dependent kinase 2 0.173057
FASN fatty acid synthase 0.172291
BIRC5 baculoviral IAP repeat containing 5 0.171286
IFNG interferon, gamma 0.171286
TRADD TNFRSF1A-associated via death domain 0.170544
GP6 glycoprotein VI (platelet) 0.169571
SCX scleraxis basic helix-loop-helix transcription factor 0.169091
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 0.166995
LGALS4 lectin, galactoside-binding, soluble, 4 0.165874
TJP1 tight junction protein 1 0.165435
DSP desmoplakin 0.164571
PARP1 poly (ADP-ribose) polymerase 1 0.163111
NEU2 sialidase 2 (cytosolic sialidase) 0.163111
CDK1 cyclin-dependent kinase 1 0.163111
IGHV3-30 immunoglobulin heavy variable 3-30 0.162109
TGM1 transglutaminase 1 0.161912
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.161716
ATR ATR serine/threonine kinase 0.161523
BBS2 Bardet-Biedl syndrome 2 0.160761
GP5 glycoprotein V (platelet) 0.160387
PIWIL1 piwi-like RNA-mediated gene silencing 1 0.159302
CTNNBIP1 catenin, beta interacting protein 1 0.158266