colforsin-7059 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the colforsin-7059 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ADA adenosine deaminase
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
AQP3 aquaporin 3 (Gill blood group)
ARHGAP32 Rho GTPase activating protein 32
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ATG13 autophagy related 13
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCL2A1 BCL2-related protein A1
BMP1 bone morphogenetic protein 1
BMP2K BMP2 inducible kinase
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEMIP cell migration inducing protein, hyaluronan binding
CEP97 centrosomal protein 97kDa
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CTH cystathionine gamma-lyase
CXCL3 chemokine (C-X-C motif) ligand 3
DBF4B DBF4 zinc finger B
DFNB31 deafness, autosomal recessive 31
DHRS9 dehydrogenase/reductase (SDR family) member 9
DMBT1 deleted in malignant brain tumors 1
DUSP1 dual specificity phosphatase 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EDIL3 EGF-like repeats and discoidin I-like domains 3
EN2 engrailed homeobox 2
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
EPHB2 EPH receptor B2
ERAP1 endoplasmic reticulum aminopeptidase 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GK glycerol kinase
GPR137 G protein-coupled receptor 137
GPR153 G protein-coupled receptor 153
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRAMD1B GRAM domain containing 1B
HBEGF heparin-binding EGF-like growth factor
HMGB3P1 high mobility group box 3 pseudogene 1
IL11 interleukin 11
IL33 interleukin 33
IRF9 interferon regulatory factor 9
ISG20 interferon stimulated exonuclease gene 20kDa
ITGB5 integrin, beta 5
KDM4A lysine (K)-specific demethylase 4A
KRT6B keratin 6B, type II
MAP7 microtubule-associated protein 7
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MARK4 MAP/microtubule affinity-regulating kinase 4
MECP2 methyl CpG binding protein 2
NCDN neurochondrin
NF1 neurofibromin 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OASL 2'-5'-oligoadenylate synthetase-like
PANK3 pantothenate kinase 3
PDE4B phosphodiesterase 4B, cAMP-specific
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PDLIM7 PDZ and LIM domain 7 (enigma)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PML promyelocytic leukemia
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTGES prostaglandin E synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RNF126P1 ring finger protein 126 pseudogene 1
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RPS17P5 ribosomal protein S17 pseudogene 5
RXRA retinoid X receptor, alpha
SAT1 spermidine/spermine N1-acetyltransferase 1
SCAF4 SR-related CTD-associated factor 4
SEC63 SEC63 homolog (S. cerevisiae)
SECISBP2 SECIS binding protein 2
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SMOX spermine oxidase
SNW1 SNW domain containing 1
SPATA2L spermatogenesis associated 2-like
SPN sialophorin
STC1 stanniocalcin 1
STK4 serine/threonine kinase 4
SYNJ1 synaptojanin 1
TAOK2 TAO kinase 2
TFPI2 tissue factor pathway inhibitor 2
TGFB2 transforming growth factor, beta 2
THBD thrombomodulin
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TRIM29 tripartite motif containing 29
TRIM3 tripartite motif containing 3
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WSCD1 WSC domain containing 1
ZNF350 zinc finger protein 350
ZNF747 zinc finger protein 747

decreased expression

Symbol Name
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
AEN apoptosis enhancing nuclease
AGO4 argonaute RISC catalytic component 4
AMIGO2 adhesion molecule with Ig-like domain 2
ANOS1 anosmin 1
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ASAP1-IT1 ASAP1 intronic transcript 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF68 chromosome 11 open reading frame 68
C16ORF45 chromosome 16 open reading frame 45
C4BPA complement component 4 binding protein, alpha
C9ORF40 chromosome 9 open reading frame 40
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCNO cyclin O
CCNT1 cyclin T1
CDADC1 cytidine and dCMP deaminase domain containing 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CDT1 chromatin licensing and DNA replication factor 1
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CORT cortistatin
CTGF connective tissue growth factor
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYR61 cysteine-rich, angiogenic inducer, 61
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DENND3 DENN/MADD domain containing 3
EPHA4 EPH receptor A4
EXOSC5 exosome component 5
FBRS fibrosin
FOXC1 forkhead box C1
FUZ fuzzy planar cell polarity protein
G0S2 G0/G1 switch 2
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GBX2 gastrulation brain homeobox 2
GCHFR GTP cyclohydrolase I feedback regulator
GNPDA1 glucosamine-6-phosphate deaminase 1
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GREB1L growth regulation by estrogen in breast cancer-like
GRPR gastrin-releasing peptide receptor
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
IL11RA interleukin 11 receptor, alpha
INHBB inhibin, beta B
KDM7A lysine (K)-specific demethylase 7A
KIAA0513 KIAA0513
KIAA0754 KIAA0754
KLHDC4 kelch domain containing 4
MAP2 microtubule-associated protein 2
MON1B MON1 secretory trafficking family member B
NDE1 nudE neurodevelopment protein 1
NPY1R neuropeptide Y receptor Y1
NYNRIN NYN domain and retroviral integrase containing
OLFML2A olfactomedin-like 2A
ORAI3 ORAI calcium release-activated calcium modulator 3
PADI2 peptidyl arginine deiminase, type II
PLD2 phospholipase D2
PLEKHA6 pleckstrin homology domain containing, family A member 6
POMT1 protein-O-mannosyltransferase 1
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRPH peripherin
PSKH1 protein serine kinase H1
PTX3 pentraxin 3, long
QSER1 glutamine and serine rich 1
RAP1GAP2 RAP1 GTPase activating protein 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RNF121 ring finger protein 121
RNF122 ring finger protein 122
S100A3 S100 calcium binding protein A3
SAMHD1 SAM domain and HD domain 1
SCIN scinderin
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SETD1B SET domain containing 1B
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SIX1 SIX homeobox 1
SMA4 glucuronidase, beta pseudogene
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SSNA1 Sjogren syndrome nuclear autoantigen 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TOR4A torsin family 4, member A
TPCN1 two pore segment channel 1
TTBK2 tau tubulin kinase 2
TUBA3C tubulin, alpha 3c
TUBB2B tubulin, beta 2B class IIb
TUBG2 tubulin, gamma 2
TXK TXK tyrosine kinase
USP36 ubiquitin specific peptidase 36
WDR76 WD repeat domain 76
WWC2 WW and C2 domain containing 2
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF215 zinc finger protein 215
ZNF286A zinc finger protein 286A
ZNF358 zinc finger protein 358
ZNF528 zinc finger protein 528
ZNF573 zinc finger protein 573