colforsin-7055 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the colforsin-7055 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ACACB acetyl-CoA carboxylase beta
ADA adenosine deaminase
ADM adrenomedullin
ADORA1 adenosine A1 receptor
AHDC1 AT hook, DNA binding motif, containing 1
AK2 adenylate kinase 2
AKR1C1 aldo-keto reductase family 1, member C1
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
AQP3 aquaporin 3 (Gill blood group)
BDKRB2 bradykinin receptor B2
C14ORF79 chromosome 14 open reading frame 79
C7ORF43 chromosome 7 open reading frame 43
CA5BP1 carbonic anhydrase VB pseudogene 1
CACYBP calcyclin binding protein
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CASP9 caspase 9, apoptosis-related cysteine peptidase
CEMIP cell migration inducing protein, hyaluronan binding
CGA glycoprotein hormones, alpha polypeptide
CHKB choline kinase beta
CXCR4 chemokine (C-X-C motif) receptor 4
DFNB31 deafness, autosomal recessive 31
DOK4 docking protein 4
EHD2 EH-domain containing 2
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EVA1B eva-1 homolog B (C. elegans)
FGFR2 fibroblast growth factor receptor 2
FH fumarate hydratase
FLJ11710 uncharacterized protein FLJ11710
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FOSL2 FOS-like antigen 2
FSCN1 fascin actin-bundling protein 1
GALK1 galactokinase 1
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GEM GTP binding protein overexpressed in skeletal muscle
GON4L gon-4-like (C. elegans)
IDI2-AS1 IDI2 antisense RNA 1
IER3 immediate early response 3
IGFBP3 insulin-like growth factor binding protein 3
IL4R interleukin 4 receptor
IRS2 insulin receptor substrate 2
ISG20 interferon stimulated exonuclease gene 20kDa
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KIF3C kinesin family member 3C
LAMP1 lysosomal-associated membrane protein 1
LRRC61 leucine rich repeat containing 61
LZTS3 leucine zipper, putative tumor suppressor family member 3
MALT1 MALT1 paracaspase
MAP4 microtubule-associated protein 4
MCF2L MCF.2 cell line derived transforming sequence-like
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYO1E myosin IE
NAV2 neuron navigator 2
NEBL nebulette
NOL6 nucleolar protein 6 (RNA-associated)
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OASL 2'-5'-oligoadenylate synthetase-like
PDE4C phosphodiesterase 4C, cAMP-specific
PDE4DIP phosphodiesterase 4D interacting protein
PHKA2 phosphorylase kinase, alpha 2 (liver)
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLAUR plasminogen activator, urokinase receptor
POR P450 (cytochrome) oxidoreductase
PPT2 palmitoyl-protein thioesterase 2
PTGES prostaglandin E synthase
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RAP1GAP RAP1 GTPase activating protein
RARA retinoic acid receptor, alpha
RFTN1 raftlin, lipid raft linker 1
RNF25 ring finger protein 25
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SIK1 salt-inducible kinase 1
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC25A44 solute carrier family 25, member 44
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SMCO4 single-pass membrane protein with coiled-coil domains 4
SNAI2 snail family zinc finger 2
SPPL2B signal peptide peptidase like 2B
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TARP TCR gamma alternate reading frame protein
TEX14 testis expressed 14
THBD thrombomodulin
TMPRSS3 transmembrane protease, serine 3
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TPCN1 two pore segment channel 1
TREX1 three prime repair exonuclease 1
WDR62 WD repeat domain 62
WIPF1 WAS/WASL interacting protein family, member 1
ZNF573 zinc finger protein 573
ZNF589 zinc finger protein 589
ZNF8 zinc finger protein 8

decreased expression

Symbol Name
ADAP2 ArfGAP with dual PH domains 2
AFF4 AF4/FMR2 family, member 4
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANXA1 annexin A1
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ATAD5 ATPase family, AAA domain containing 5
BAHCC1 BAH domain and coiled-coil containing 1
BBS1 Bardet-Biedl syndrome 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
C1ORF35 chromosome 1 open reading frame 35
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C21ORF91 chromosome 21 open reading frame 91
C9ORF114 chromosome 9 open reading frame 114
CCDC85C coiled-coil domain containing 85C
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDK3 cyclin-dependent kinase 3
CEP97 centrosomal protein 97kDa
CHRM3 cholinergic receptor, muscarinic 3
CLDN11 claudin 11
CPA4 carboxypeptidase A4
CPTP ceramide-1-phosphate transfer protein
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DOC2A double C2-like domains, alpha
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ELMO3 engulfment and cell motility 3
EMID1 EMI domain containing 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
FGD6 FYVE, RhoGEF and PH domain containing 6
FILIP1L filamin A interacting protein 1-like
FLRT3 fibronectin leucine rich transmembrane protein 3
GADD45A growth arrest and DNA-damage-inducible, alpha
GMEB1 glucocorticoid modulatory element binding protein 1
GP6 glycoprotein VI (platelet)
GPR87 G protein-coupled receptor 87
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HCFC2 host cell factor C2
HIST1H2BJ histone cluster 1, H2bj
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IQSEC2 IQ motif and Sec7 domain 2
IRF1 interferon regulatory factor 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LHFPL2 lipoma HMGIC fusion partner-like 2
LINC00597 long intergenic non-protein coding RNA 597
LMNB1 lamin B1
LRRC37A2 leucine rich repeat containing 37, member A2
LYPD1 LY6/PLAUR domain containing 1
LYPLA2P1 lysophospholipase II pseudogene 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAPK12 mitogen-activated protein kinase 12
MAPKBP1 mitogen-activated protein kinase binding protein 1
MITF microphthalmia-associated transcription factor
MPDU1 mannose-P-dolichol utilization defect 1
MXD3 MAX dimerization protein 3
MYOZ3 myozenin 3
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PRB4 proline-rich protein BstNI subfamily 4
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PRR3 proline rich 3
RAB33B RAB33B, member RAS oncogene family
RGS2 regulator of G-protein signaling 2
RNF126P1 ring finger protein 126 pseudogene 1
SEC14L2 SEC14-like 2 (S. cerevisiae)
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SGCE sarcoglycan, epsilon
SIRT6 sirtuin 6
SIX1 SIX homeobox 1
SLC12A9 solute carrier family 12, member 9
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SPRYD7 SPRY domain containing 7
SRD5A3 steroid 5 alpha-reductase 3
STON1 stonin 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TCP10 t-complex 10
TET3 tet methylcytosine dioxygenase 3
TMC7 transmembrane channel-like 7
TMEM53 transmembrane protein 53
TUBA3D tubulin, alpha 3d
UBTD1 ubiquitin domain containing 1
UPK3B uroplakin 3B
USP6NL USP6 N-terminal like
XK X-linked Kx blood group
YPEL1 yippee-like 1 (Drosophila)
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF136 zinc finger protein 136
ZNF253 zinc finger protein 253
ZNF668 zinc finger protein 668
ZNF675 zinc finger protein 675
ZNF768 zinc finger protein 768