coated pit Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes. (Gene Ontology, GO_0005905)
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Genes

193 proteins co-occuring with the coated pit cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
TF transferrin 1.85113
EPS15 epidermal growth factor receptor pathway substrate 15 1.77405
LRP2 low density lipoprotein receptor-related protein 2 1.70816
TFRC transferrin receptor 1.56674
HAS1 hyaluronan synthase 1 1.5656
AKAP13 A kinase (PRKA) anchor protein 13 1.56275
AP2M1 adaptor-related protein complex 2, mu 1 subunit 1.4774
LDLR low density lipoprotein receptor 1.41923
FTL ferritin, light polypeptide 1.40746
FTH1 ferritin, heavy polypeptide 1 1.40466
AP1M2 adaptor-related protein complex 1, mu 2 subunit 1.3935
ARRB2 arrestin, beta 2 1.39239
SNAP91 synaptosomal-associated protein, 91kDa 1.36692
ARRB1 arrestin, beta 1 1.31681
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 1.2889
EPN1 epsin 1 1.25495
MYO1G myosin IG 1.24131
AP2B1 adaptor-related protein complex 2, beta 1 subunit 1.18389
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 1.17722
KRT38 keratin 38, type I 1.14955
DNM1 dynamin 1 1.1475
AMPH amphiphysin 1.08323
SNX9 sorting nexin 9 1.03829
ADRB2 adrenoceptor beta 2, surface 1.03378
EGFR epidermal growth factor receptor 1.02729
CAV1 caveolin 1, caveolae protein, 22kDa 1.02281
GAK cyclin G associated kinase 1.00103
SH3GL2 SH3-domain GRB2-like 2 0.987806
ALB albumin 0.975166
HIP1R huntingtin interacting protein 1 related 0.97323
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 0.959268
SYNJ1 synaptojanin 1 0.898572
ADRBK1 adrenergic, beta, receptor kinase 1 0.887474
INSR insulin receptor 0.880094
GRB2 growth factor receptor-bound protein 2 0.875028
PICALM phosphatidylinositol binding clathrin assembly protein 0.858473
DNM2 dynamin 2 0.848369
AAK1 AP2 associated kinase 1 0.843318
HIP1 huntingtin interacting protein 1 0.840105
INS insulin 0.834138
MRC1 mannose receptor, C type 1 0.826794
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.821288
EEA1 early endosome antigen 1 0.81624
HLA-A major histocompatibility complex, class I, A 0.796062
ASGR2 asialoglycoprotein receptor 2 0.794687
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.794687
ASGR1 asialoglycoprotein receptor 1 0.793313
MYO6 myosin VI 0.76726
KRT36 keratin 36, type I 0.75181
CLINT1 clathrin interactor 1 0.737363
BIN1 bridging integrator 1 0.723026
CD4 CD4 molecule 0.721242
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1 0.711465
HSPA8 heat shock 70kDa protein 8 0.711022
M6PR mannose-6-phosphate receptor (cation dependent) 0.697784
LDLRAP1 low density lipoprotein receptor adaptor protein 1 0.669425
ACPP acid phosphatase, prostate 0.612895
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 0.606128
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 0.604862
LAMP1 lysosomal-associated membrane protein 1 0.580922
STON2 stonin 2 0.579669
CEMIP cell migration inducing protein, hyaluronan binding 0.576329
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) 0.560114
KRT37 keratin 37, type I 0.5568
APOE apolipoprotein E 0.549773
FCHO1 FCH domain only 1 0.543176
MGAT4C MGAT4 family, member C 0.541117
ITSN2 intersectin 2 0.538649
RNF216 ring finger protein 216 0.535361
PLEK pleckstrin 0.53413
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 0.527979
PRNP prion protein 0.523476
CDHR5 cadherin-related family member 5 0.514085
REP15 RAB15 effector protein 0.514085
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0.513677
NECAP1 NECAP endocytosis associated 1 0.4958
RGS19 regulator of G-protein signaling 19 0.492157
HMHA1 histocompatibility (minor) HA-1 0.489731
DSEL dermatan sulfate epimerase-like 0.488923
TGOLN2 trans-golgi network protein 2 0.487711
SNX21 sorting nexin family member 21 0.4865
OCRL oculocerebrorenal syndrome of Lowe 0.484483
ERBB2 erb-b2 receptor tyrosine kinase 2 0.481258
RALBP1 ralA binding protein 1 0.481258
A2M alpha-2-macroglobulin 0.47844
CCRL2 chemokine (C-C motif) receptor-like 2 0.469203
GHR growth hormone receptor 0.458006
STAB2 stabilin 2 0.455613
NAV2 neuron navigator 2 0.440124
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 0.43696
ANXA6 annexin A6 0.432224
REPS1 RALBP1 associated Eps domain containing 1 0.428678
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 0.424353
ARF6 ADP-ribosylation factor 6 0.415728
DPP4 dipeptidyl-peptidase 4 0.402859
PRKCDBP protein kinase C, delta binding protein 0.391615
SYK spleen tyrosine kinase 0.390068
AP2A2 adaptor-related protein complex 2, alpha 2 subunit 0.389296
FCRLB Fc receptor-like B 0.38428
EPN3 epsin 3 0.380814
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.368919
PGRMC1 progesterone receptor membrane component 1 0.357467
GIPC1 GIPC PDZ domain containing family, member 1 0.356705
FIG4 FIG4 phosphoinositide 5-phosphatase 0.356324
ARR3 arrestin 3, retinal (X-arrestin) 0.349484
ACP2 acid phosphatase 2, lysosomal 0.345692
LCK LCK proto-oncogene, Src family tyrosine kinase 0.345692
CCL17 chemokine (C-C motif) ligand 17 0.339639
FCHO2 FCH domain only 2 0.338884
HYAL1 hyaluronoglucosaminidase 1 0.33511
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.333979
MEGF10 multiple EGF-like-domains 10 0.331719
TCN2 transcobalamin II 0.330589
CTSD cathepsin D 0.328332
FN1 fibronectin 1 0.319702
LYN LYN proto-oncogene, Src family tyrosine kinase 0.314465
FCGRT Fc fragment of IgG, receptor, transporter, alpha 0.311851
SH3BP4 SH3-domain binding protein 4 0.305515
VLDLR very low density lipoprotein receptor 0.303655
IGF2R insulin-like growth factor 2 receptor 0.302912
BRD8 bromodomain containing 8 0.301425
ITSN1 intersectin 1 (SH3 domain protein) 0.301054
PDGFD platelet derived growth factor D 0.294007
NTS neurotensin 0.285507
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 0.284032
CD80 CD80 molecule 0.273
ERVW-1 endogenous retrovirus group W, member 1 0.2708
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 0.269335
ADCY2 adenylate cyclase 2 (brain) 0.266774
GNRHR2 gonadotropin-releasing hormone (type 2) receptor 2, pseudogene 0.259837
TRHR thyrotropin-releasing hormone receptor 0.257289
DNAH8 dynein, axonemal, heavy chain 8 0.256925
RFX1 regulatory factor X, 1 (influences HLA class II expression) 0.25547
GLB1 galactosidase, beta 1 0.254017
GSTA3 glutathione S-transferase alpha 3 0.250751
GSTA4 glutathione S-transferase alpha 4 0.24894
GSTA2 glutathione S-transferase alpha 2 0.24894
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 0.248578
SNX15 sorting nexin 15 0.248578
GSTA1 glutathione S-transferase alpha 1 0.246769
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1 0.24424
CD79A CD79a molecule, immunoglobulin-associated alpha 0.240996
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.240636
IL2 interleukin 2 0.240636
SNX18 sorting nexin 18 0.237042
HLA-B major histocompatibility complex, class I, B 0.228819
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 0.225976
HLA-C major histocompatibility complex, class I, C 0.22279
ERBB4 erb-b2 receptor tyrosine kinase 4 0.222436
SHBG sex hormone-binding globulin 0.221025
LPL lipoprotein lipase 0.220321
DNMBP dynamin binding protein 0.219265
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 0.217511
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 0.214714
FOLR2 folate receptor 2 (fetal) 0.213322
THBD thrombomodulin 0.212627
OR3A1 olfactory receptor, family 3, subfamily A, member 1 0.209858
DENND1A DENN/MADD domain containing 1A 0.208137
RAB5A RAB5A, member RAS oncogene family 0.204039
ANKRD23 ankyrin repeat domain 23 0.203022
ERBB3 erb-b2 receptor tyrosine kinase 3 0.200663
NTSR1 neurotensin receptor 1 (high affinity) 0.197662
CTTN cortactin 0.197662
PODN podocan 0.197662
BCR breakpoint cluster region 0.197662
LY75 lymphocyte antigen 75 0.19733
SST somatostatin 0.194045
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 0.194045
NUMB numb homolog (Drosophila) 0.192746
APOB apolipoprotein B 0.190175
B2M beta-2-microglobulin 0.18796
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 0.185777
WNK1 WNK lysine deficient protein kinase 1 0.183025
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.180339
CERS2 ceramide synthase 2 0.178588
CD300A CD300a molecule 0.178588
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 0.178299
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.175188
SCGB2A1 secretoglobin, family 2A, member 1 0.173814
COPE coatomer protein complex, subunit epsilon 0.173543
TLL1 tolloid-like 1 0.172735
CHRM2 cholinergic receptor, muscarinic 2 0.172735
FLOT1 flotillin 1 0.170629
CXCR2 chemokine (C-X-C motif) receptor 2 0.170629
FOLR1 folate receptor 1 (adult) 0.169604
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 0.165231
THY1 Thy-1 cell surface antigen 0.164089
EHD1 EH-domain containing 1 0.163865
PDGFB platelet-derived growth factor beta polypeptide 0.162546
SYNJ2 synaptojanin 2 0.16233
OPRM1 opioid receptor, mu 1 0.160863
NBPF10 neuroblastoma breakpoint family, member 10 0.160658
TXNDC17 thioredoxin domain containing 17 0.159856