coated pit Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes. (Gene Ontology, GO_0005905)
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Genes

59 proteins localized to the coated pit cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
RAB35 RAB35, member RAS oncogene family 0.663342
CLTA clathrin, light chain A 0.663342
FNBP1 formin binding protein 1 0.663342
LDLR low density lipoprotein receptor 0.663342
ACKR3 atypical chemokine receptor 3 0.663342
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.663342
AP1S3 adaptor-related protein complex 1, sigma 3 subunit 0.663342
AP4S1 adaptor-related protein complex 4, sigma 1 subunit 0.663342
TNK2 tyrosine kinase, non-receptor, 2 0.663342
REPS1 RALBP1 associated Eps domain containing 1 0.663342
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 0.663342
AP4M1 adaptor-related protein complex 4, mu 1 subunit 0.663342
EPS15 epidermal growth factor receptor pathway substrate 15 0.663342
TFRC transferrin receptor 0.663342
AP2A1 adaptor-related protein complex 2, alpha 1 subunit 0.663342
APP amyloid beta (A4) precursor protein 0.663342
CLTB clathrin, light chain B 0.663342
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 0.663342
PICALM phosphatidylinositol binding clathrin assembly protein 0.663342
TF transferrin 0.663342
LRP2 low density lipoprotein receptor-related protein 2 0.663342
MYO6 myosin VI 0.663342
CEMIP cell migration inducing protein, hyaluronan binding 0.663342
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1 0.663342
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.663342
FCHO2 FCH domain only 2 0.663342
FCHO1 FCH domain only 1 0.663342
ITSN1 intersectin 1 (SH3 domain protein) 0.663342
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.663342
CLTCL1 clathrin, heavy chain-like 1 0.663342
VLDLR very low density lipoprotein receptor 0.663342
NECAP2 NECAP endocytosis associated 2 0.237908
SORT1 sortilin 1 0.237908
RAMP2 receptor (G protein-coupled) activity modifying protein 2 0.237908
SELE selectin E 0.237908
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.237908
LRP12 low density lipoprotein receptor-related protein 12 0.098109
AP4B1 adaptor-related protein complex 4, beta 1 subunit 0.098109
AAK1 AP2 associated kinase 1 0.098109
LRP10 low density lipoprotein receptor-related protein 10 0.098109
AP2B1 adaptor-related protein complex 2, beta 1 subunit 0.098109
LRP3 low density lipoprotein receptor-related protein 3 0.098109
SH3BP4 SH3-domain binding protein 4 0.098109
SNAP91 synaptosomal-associated protein, 91kDa 0.098109
AP2A2 adaptor-related protein complex 2, alpha 2 subunit 0.098109
ATAT1 alpha tubulin acetyltransferase 1 0.098109
ARRB1 arrestin, beta 1 0.098109
ARRB2 arrestin, beta 2 0.098109
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit 0.098109
EPN1 epsin 1 0.098109
OCRL oculocerebrorenal syndrome of Lowe 0.098109
DNM1L dynamin 1-like 0.098109
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 0.03318
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 0.03318
HIP1R huntingtin interacting protein 1 related 0.03318
NECAP1 NECAP endocytosis associated 1 0.03318
CUBN cubilin (intrinsic factor-cobalamin receptor) 0.03318
EPN3 epsin 3 0.03318
CLTC clathrin, heavy chain (Hc) 0.03318