| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the clozapine-5630 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
| AKAP6 | A kinase (PRKA) anchor protein 6 |
| ANO1 | anoctamin 1, calcium activated chloride channel |
| APAF1 | apoptotic peptidase activating factor 1 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 |
| ATG10 | autophagy related 10 |
| ATXN2L | ataxin 2-like |
| C2CD2L | C2CD2-like |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CARTPT | CART prepropeptide |
| CD53 | CD53 molecule |
| CD6 | CD6 molecule |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CDK18 | cyclin-dependent kinase 18 |
| CEP295 | centrosomal protein 295kDa |
| CFAP69 | cilia and flagella associated protein 69 |
| CIB2 | calcium and integrin binding family member 2 |
| CKMT2 | creatine kinase, mitochondrial 2 (sarcomeric) |
| CLSTN3 | calsyntenin 3 |
| CNN1 | calponin 1, basic, smooth muscle |
| COL17A1 | collagen, type XVII, alpha 1 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CSNK1G1 | casein kinase 1, gamma 1 |
| CTIF | CBP80/20-dependent translation initiation factor |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYTH4 | cytohesin 4 |
| DCTN1 | dynactin 1 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| DPY19L1 | dpy-19-like 1 (C. elegans) |
| DUX1 | double homeobox 1 |
| EDNRA | endothelin receptor type A |
| EGFL7 | EGF-like-domain, multiple 7 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) |
| ELL | elongation factor RNA polymerase II |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FPR1 | formyl peptide receptor 1 |
| GDPD2 | glycerophosphodiester phosphodiesterase domain containing 2 |
| GLYAT | glycine-N-acyltransferase |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GPSM3 | G-protein signaling modulator 3 |
| HFE | hemochromatosis |
| HOXB5 | homeobox B5 |
| HR | hair growth associated |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KIF5A | kinesin family member 5A |
| KIR2DL1 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KRT17 | keratin 17, type I |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LHX2 | LIM homeobox 2 |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LOC440895 | two pore channel 3 pseudogene |
| LOC51145 | uncharacterized LOC51145 |
| MC5R | melanocortin 5 receptor |
| MMP25 | matrix metallopeptidase 25 |
| MOB3B | MOB kinase activator 3B |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MX2 | MX dynamin-like GTPase 2 |
| MYH14 | myosin, heavy chain 14, non-muscle |
| NOVA2 | neuro-oncological ventral antigen 2 |
| PAX2 | paired box 2 |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PLK3 | polo-like kinase 3 |
| PON1 | paraoxonase 1 |
| PON3 | paraoxonase 3 |
| POU6F1 | POU class 6 homeobox 1 |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme |
| PSORS1C1 | psoriasis susceptibility 1 candidate 1 |
| RAP2A | RAP2A, member of RAS oncogene family |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| STAC | SH3 and cysteine rich domain |
| STXBP5L | syntaxin binding protein 5-like |
| TBC1D22B | TBC1 domain family, member 22B |
| TPMT | thiopurine S-methyltransferase |
| TRIL | TLR4 interactor with leucine-rich repeats |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| ULBP1 | UL16 binding protein 1 |
| USP2 | ubiquitin specific peptidase 2 |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| VCL | vinculin |
| ZBED4 | zinc finger, BED-type containing 4 |
| ZNF467 | zinc finger protein 467 |
| ZNF695 | zinc finger protein 695 |
| ZNF76 | zinc finger protein 76 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ABLIM3 | actin binding LIM protein family, member 3 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ALS2CL | ALS2 C-terminal like |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCDC134 | coiled-coil domain containing 134 |
| CCDC9 | coiled-coil domain containing 9 |
| CCNO | cyclin O |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHST10 | carbohydrate sulfotransferase 10 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CRLF1 | cytokine receptor-like factor 1 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTSK | cathepsin K |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DEAF1 | DEAF1 transcription factor |
| DMTN | dematin actin binding protein |
| DRD1 | dopamine receptor D1 |
| DUSP8 | dual specificity phosphatase 8 |
| EFHD2 | EF-hand domain family, member D2 |
| EVPL | envoplakin |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FAM155B | family with sequence similarity 155, member B |
| FAM204A | family with sequence similarity 204, member A |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FRK | fyn-related Src family tyrosine kinase |
| FYCO1 | FYVE and coiled-coil domain containing 1 |
| GFI1 | growth factor independent 1 transcription repressor |
| GMPR | guanosine monophosphate reductase |
| GPR27 | G protein-coupled receptor 27 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC11 | histone deacetylase 11 |
| HOXB2 | homeobox B2 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| INPP1 | inositol polyphosphate-1-phosphatase |
| KIAA0319L | KIAA0319-like |
| KIAA0556 | KIAA0556 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRRC61 | leucine rich repeat containing 61 |
| MALL | mal, T-cell differentiation protein-like |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| NBEAL2 | neurobeachin-like 2 |
| NRSN2 | neurensin 2 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDE8B | phosphodiesterase 8B |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLD2 | phospholipase D2 |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PPM1F | protein phosphatase, Mg2+/Mn2+ dependent, 1F |
| PRR14L | proline rich 14-like |
| PXN | paxillin |
| RGS2 | regulator of G-protein signaling 2 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF39 | ring finger protein 39 |
| RPL10L | ribosomal protein L10-like |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RUNDC3B | RUN domain containing 3B |
| S100A6 | S100 calcium binding protein A6 |
| S100A9 | S100 calcium binding protein A9 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SDC3 | syndecan 3 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SSBP3 | single stranded DNA binding protein 3 |
| ST5 | suppression of tumorigenicity 5 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TUBA3C | tubulin, alpha 3c |
| UBTD1 | ubiquitin domain containing 1 |
| VAX2 | ventral anterior homeobox 2 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF34 | zinc finger protein 34 |
| ZNF573 | zinc finger protein 573 |
| ZNF701 | zinc finger protein 701 |
| ZNF8 | zinc finger protein 8 |
