Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the clozapine-416 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACTA2 | actin, alpha 2, smooth muscle, aorta |
ANKRD12 | ankyrin repeat domain 12 |
ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 |
ARSF | arylsulfatase F |
ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
ASIC3 | acid sensing (proton gated) ion channel 3 |
AVPR1B | arginine vasopressin receptor 1B |
BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
BNIP1 | BCL2/adenovirus E1B 19kDa interacting protein 1 |
C19ORF66 | chromosome 19 open reading frame 66 |
C20ORF27 | chromosome 20 open reading frame 27 |
CANX | calnexin |
CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
CHAF1A | chromatin assembly factor 1, subunit A (p150) |
CLCN7 | chloride channel, voltage-sensitive 7 |
CNTD2 | cyclin N-terminal domain containing 2 |
CORO1B | coronin, actin binding protein, 1B |
CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
DLEC1 | deleted in lung and esophageal cancer 1 |
DUS2 | dihydrouridine synthase 2 |
ENG | endoglin |
ENOX2 | ecto-NOX disulfide-thiol exchanger 2 |
EPOR | erythropoietin receptor |
FAM153A | family with sequence similarity 153, member A |
FGF18 | fibroblast growth factor 18 |
FLJ11292 | |
FN1 | fibronectin 1 |
FOLR2 | folate receptor 2 (fetal) |
GAN | gigaxonin |
GDF11 | growth differentiation factor 11 |
GINS3 | GINS complex subunit 3 (Psf3 homolog) |
GLS | glutaminase |
GRIP2 | glutamate receptor interacting protein 2 |
HOXB7 | homeobox B7 |
HPS1 | Hermansky-Pudlak syndrome 1 |
IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
IRX4 | iroquois homeobox 4 |
ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
KLHL3 | kelch-like family member 3 |
LENEP | lens epithelial protein |
LIAS | lipoic acid synthetase |
LZTS1 | leucine zipper, putative tumor suppressor 1 |
MPPE1 | metallophosphoesterase 1 |
NADK | NAD kinase |
NDN | necdin, melanoma antigen (MAGE) family member |
NF2 | neurofibromin 2 (merlin) |
NID2 | nidogen 2 (osteonidogen) |
NKIRAS2 | NFKB inhibitor interacting Ras-like 2 |
NNAT | neuronatin |
NRGN | neurogranin (protein kinase C substrate, RC3) |
OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
PCDH7 | protocadherin 7 |
PDCD2 | programmed cell death 2 |
PDLIM7 | PDZ and LIM domain 7 (enigma) |
PHEX | phosphate regulating endopeptidase homolog, X-linked |
PHF20 | PHD finger protein 20 |
PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
PLEC | plectin |
PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
POFUT2 | protein O-fucosyltransferase 2 |
POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
RAB8B | RAB8B, member RAS oncogene family |
RECQL5 | RecQ protein-like 5 |
RHO | rhodopsin |
RRAS | related RAS viral (r-ras) oncogene homolog |
RRBP1 | ribosome binding protein 1 |
RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
RUNDC3A | RUN domain containing 3A |
SAP18 | Sin3A-associated protein, 18kDa |
SEZ6L | seizure related 6 homolog (mouse)-like |
SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 |
SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 |
SNX6 | sorting nexin 6 |
SOD2 | superoxide dismutase 2, mitochondrial |
SOS2 | son of sevenless homolog 2 (Drosophila) |
SOX21 | SRY (sex determining region Y)-box 21 |
SUGP2 | SURP and G patch domain containing 2 |
SURF2 | surfeit 2 |
TCEAL1 | transcription elongation factor A (SII)-like 1 |
TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
TMPRSS2 | transmembrane protease, serine 2 |
TNFSF8 | tumor necrosis factor (ligand) superfamily, member 8 |
TP53TG1 | TP53 target 1 (non-protein coding) |
TRAC | T cell receptor alpha constant |
TYMP | thymidine phosphorylase |
UBE2I | ubiquitin-conjugating enzyme E2I |
UBE3A | ubiquitin protein ligase E3A |
VIM | vimentin |
VRK3 | vaccinia related kinase 3 |
WIZ | widely interspaced zinc finger motifs |
ZMIZ2 | zinc finger, MIZ-type containing 2 |
ZNF408 | zinc finger protein 408 |
Symbol | Name |
---|---|
A4GNT | alpha-1,4-N-acetylglucosaminyltransferase |
AAAS | achalasia, adrenocortical insufficiency, alacrimia |
AMDHD2 | amidohydrolase domain containing 2 |
APEX2 | APEX nuclease (apurinic/apyrimidinic endonuclease) 2 |
APOC4 | apolipoprotein C-IV |
ATP7B | ATPase, Cu++ transporting, beta polypeptide |
CAMKV | CaM kinase-like vesicle-associated |
CCL16 | chemokine (C-C motif) ligand 16 |
CD300C | CD300c molecule |
CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) |
CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
CENPO | centromere protein O |
CFAP70 | cilia and flagella associated protein 70 |
CHKB | choline kinase beta |
CLDN14 | claudin 14 |
CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
CPTP | ceramide-1-phosphate transfer protein |
CRMP1 | collapsin response mediator protein 1 |
CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 |
CTAGE9 | CTAGE family, member 9 |
CTLA4 | cytotoxic T-lymphocyte-associated protein 4 |
CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
DGKD | diacylglycerol kinase, delta 130kDa |
DSCAM | Down syndrome cell adhesion molecule |
DYSF | dysferlin |
ECE2 | endothelin converting enzyme 2 |
EPM2AIP1 | EPM2A (laforin) interacting protein 1 |
FAM46C | family with sequence similarity 46, member C |
FGF16 | fibroblast growth factor 16 |
FSCN3 | fascin actin-bundling protein 3, testicular |
FTCD | formimidoyltransferase cyclodeaminase |
GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
GLB1L | galactosidase, beta 1-like |
GLRA2 | glycine receptor, alpha 2 |
GPALPP1 | GPALPP motifs containing 1 |
GREB1L | growth regulation by estrogen in breast cancer-like |
GSTCD | glutathione S-transferase, C-terminal domain containing |
GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
HAND1 | heart and neural crest derivatives expressed 1 |
HIST1H2AI | histone cluster 1, H2ai |
HOXB1 | homeobox B1 |
HPSE | heparanase |
IFI30 | interferon, gamma-inducible protein 30 |
IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 |
IL15RA | interleukin 15 receptor, alpha |
IRS4 | insulin receptor substrate 4 |
KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
LGMN | legumain |
LRRC20 | leucine rich repeat containing 20 |
LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
LYRM2 | LYR motif containing 2 |
MAD2L1BP | MAD2L1 binding protein |
MAGEB2 | melanoma antigen family B2 |
MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
MEFV | Mediterranean fever |
MNT | MAX network transcriptional repressor |
N4BP3 | NEDD4 binding protein 3 |
NIP7 | NIP7, nucleolar pre-rRNA processing protein |
NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 |
OR2H1 | olfactory receptor, family 2, subfamily H, member 1 |
OR2S2 | olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene) |
OR7A17 | olfactory receptor, family 7, subfamily A, member 17 |
PDZD7 | PDZ domain containing 7 |
PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
PQLC1 | PQ loop repeat containing 1 |
RAI14 | retinoic acid induced 14 |
SCIN | scinderin |
SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
SGK2 | serum/glucocorticoid regulated kinase 2 |
SLC24A2 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 |
SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
SOD3 | superoxide dismutase 3, extracellular |
SPINK5 | serine peptidase inhibitor, Kazal type 5 |
SREK1IP1 | SREK1-interacting protein 1 |
SYNDIG1 | synapse differentiation inducing 1 |
TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
TLR5 | toll-like receptor 5 |
TMEM168 | transmembrane protein 168 |
TMEM19 | transmembrane protein 19 |
TMEM8B | transmembrane protein 8B |
TRAF5 | TNF receptor-associated factor 5 |
TVP23B | trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) |
WDR76 | WD repeat domain 76 |
WNT1 | wingless-type MMTV integration site family, member 1 |
WT1-AS | WT1 antisense RNA |
ZNF189 | zinc finger protein 189 |
ZNF195 | zinc finger protein 195 |
ZNF33B | zinc finger protein 33B |
ZNF35 | zinc finger protein 35 |
ZNF432 | zinc finger protein 432 |
ZSCAN9 | zinc finger and SCAN domain containing 9 |