Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the clozapine-2644 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
A1CF | APOBEC1 complementation factor |
ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
ACAA2 | acetyl-CoA acyltransferase 2 |
AGFG2 | ArfGAP with FG repeats 2 |
ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 |
ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
BEND5 | BEN domain containing 5 |
BIN1 | bridging integrator 1 |
C10ORF95 | chromosome 10 open reading frame 95 |
C1QL1 | complement component 1, q subcomponent-like 1 |
C22ORF46 | chromosome 22 open reading frame 46 |
CASP5 | caspase 5, apoptosis-related cysteine peptidase |
CD300A | CD300a molecule |
CD6 | CD6 molecule |
CDHR2 | cadherin-related family member 2 |
CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
COL1A1 | collagen, type I, alpha 1 |
COL4A1 | collagen, type IV, alpha 1 |
CPNE7 | copine VII |
CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
CYTH4 | cytohesin 4 |
DMTN | dematin actin binding protein |
DOK2 | docking protein 2, 56kDa |
DUSP1 | dual specificity phosphatase 1 |
ELL | elongation factor RNA polymerase II |
ELL2 | elongation factor, RNA polymerase II, 2 |
ELOVL5 | ELOVL fatty acid elongase 5 |
FAM155A | family with sequence similarity 155, member A |
FAM184A | family with sequence similarity 184, member A |
FGF6 | fibroblast growth factor 6 |
FH | fumarate hydratase |
FLOT2 | flotillin 2 |
FOXN2 | forkhead box N2 |
FRMPD1 | FERM and PDZ domain containing 1 |
GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
HES2 | hes family bHLH transcription factor 2 |
HR | hair growth associated |
IGLJ3 | immunoglobulin lambda joining 3 |
INHBC | inhibin, beta C |
INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
IQSEC2 | IQ motif and Sec7 domain 2 |
JUN | jun proto-oncogene |
KLK7 | kallikrein-related peptidase 7 |
KRT83 | keratin 83, type II |
LAMA4 | laminin, alpha 4 |
LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
LRRC48 | leucine rich repeat containing 48 |
LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
MARK4 | MAP/microtubule affinity-regulating kinase 4 |
METTL7A | methyltransferase like 7A |
MOCS1 | molybdenum cofactor synthesis 1 |
NEB | nebulin |
NOL12 | nucleolar protein 12 |
NPTX1 | neuronal pentraxin I |
NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
ONECUT2 | one cut homeobox 2 |
PARVB | parvin, beta |
PAX8 | paired box 8 |
PHF7 | PHD finger protein 7 |
PIN1P1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 |
PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
POFUT1 | protein O-fucosyltransferase 1 |
PPARD | peroxisome proliferator-activated receptor delta |
PRB3 | proline-rich protein BstNI subfamily 3 |
PRKCA | protein kinase C, alpha |
PRKCE | protein kinase C, epsilon |
PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
RABGAP1L | RAB GTPase activating protein 1-like |
RNF43 | ring finger protein 43 |
RPL23AP32 | ribosomal protein L23a pseudogene 32 |
RPS4Y1 | ribosomal protein S4, Y-linked 1 |
RUNX1 | runt-related transcription factor 1 |
SENP7 | SUMO1/sentrin specific peptidase 7 |
SH2D1A | SH2 domain containing 1A |
SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
SLIT1 | slit homolog 1 (Drosophila) |
SPAG8 | sperm associated antigen 8 |
SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
SPTBN1 | spectrin, beta, non-erythrocytic 1 |
STMN3 | stathmin-like 3 |
TAS2R9 | taste receptor, type 2, member 9 |
TDRKH | tudor and KH domain containing |
TGFB1 | transforming growth factor, beta 1 |
TMCC2 | transmembrane and coiled-coil domain family 2 |
TRAC | T cell receptor alpha constant |
UBXN1 | UBX domain protein 1 |
UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
VWA5A | von Willebrand factor A domain containing 5A |
XYLB | xylulokinase homolog (H. influenzae) |
ZFP37 | ZFP37 zinc finger protein |
ZNF37BP | zinc finger protein 37B, pseudogene |
ZNF771 | zinc finger protein 771 |
Symbol | Name |
---|---|
ADCY6 | adenylate cyclase 6 |
ADORA2B | adenosine A2b receptor |
ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
ANKRD40 | ankyrin repeat domain 40 |
ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
ARRB1 | arrestin, beta 1 |
ATAD3A | ATPase family, AAA domain containing 3A |
AXIN1 | axin 1 |
B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
BTBD2 | BTB (POZ) domain containing 2 |
C11ORF30 | chromosome 11 open reading frame 30 |
CBX7 | chromobox homolog 7 |
CCDC85C | coiled-coil domain containing 85C |
CD79B | CD79b molecule, immunoglobulin-associated beta |
CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
CHKB | choline kinase beta |
CLASP1 | cytoplasmic linker associated protein 1 |
CLCN5 | chloride channel, voltage-sensitive 5 |
CLDN15 | claudin 15 |
CLK1 | CDC-like kinase 1 |
CTNNBIP1 | catenin, beta interacting protein 1 |
CXORF56 | chromosome X open reading frame 56 |
DNA2 | DNA replication helicase/nuclease 2 |
EFNA3 | ephrin-A3 |
EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
FBRS | fibrosin |
FILIP1L | filamin A interacting protein 1-like |
GID4 | GID complex subunit 4 |
GLCE | glucuronic acid epimerase |
GMEB1 | glucocorticoid modulatory element binding protein 1 |
GRPR | gastrin-releasing peptide receptor |
HOOK1 | hook microtubule-tethering protein 1 |
HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
KIF13B | kinesin family member 13B |
KIFAP3 | kinesin-associated protein 3 |
KLF3 | Kruppel-like factor 3 (basic) |
LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
LIG4 | ligase IV, DNA, ATP-dependent |
LINC00115 | long intergenic non-protein coding RNA 115 |
LINC00339 | long intergenic non-protein coding RNA 339 |
LRRC20 | leucine rich repeat containing 20 |
LY6G6C | lymphocyte antigen 6 complex, locus G6C |
LYPD1 | LY6/PLAUR domain containing 1 |
MANEA | mannosidase, endo-alpha |
MAP1S | microtubule-associated protein 1S |
MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
MED24 | mediator complex subunit 24 |
MEIS1 | Meis homeobox 1 |
MTRF1 | mitochondrial translational release factor 1 |
MVD | mevalonate (diphospho) decarboxylase |
NKX3-2 | NK3 homeobox 2 |
NPFFR1 | neuropeptide FF receptor 1 |
NPM3 | nucleophosmin/nucleoplasmin 3 |
NUBPL | nucleotide binding protein-like |
OLFML2A | olfactomedin-like 2A |
PADI2 | peptidyl arginine deiminase, type II |
PEX26 | peroxisomal biogenesis factor 26 |
PHEX | phosphate regulating endopeptidase homolog, X-linked |
PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
PMCH | pro-melanin-concentrating hormone |
POLE | polymerase (DNA directed), epsilon, catalytic subunit |
POLL | polymerase (DNA directed), lambda |
PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
QTRT1 | queuine tRNA-ribosyltransferase 1 |
RARS | arginyl-tRNA synthetase |
RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
RNF121 | ring finger protein 121 |
RNF141 | ring finger protein 141 |
RPAIN | RPA interacting protein |
SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
SLC12A9 | solute carrier family 12, member 9 |
SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
SPG11 | spastic paraplegia 11 (autosomal recessive) |
SPINK5 | serine peptidase inhibitor, Kazal type 5 |
SSFA2 | sperm specific antigen 2 |
STX1A | syntaxin 1A (brain) |
TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
TCTN2 | tectonic family member 2 |
TFB1M | transcription factor B1, mitochondrial |
TICAM1 | toll-like receptor adaptor molecule 1 |
TMEM180 | transmembrane protein 180 |
TMEM62 | transmembrane protein 62 |
TYW1 | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) |
UBXN8 | UBX domain protein 8 |
ZBTB22 | zinc finger and BTB domain containing 22 |
ZBTB25 | zinc finger and BTB domain containing 25 |
ZMAT5 | zinc finger, matrin-type 5 |
ZNF329 | zinc finger protein 329 |
ZNF573 | zinc finger protein 573 |
ZNF74 | zinc finger protein 74 |
ZNF770 | zinc finger protein 770 |
ZNRD1-AS1 | ZNRD1 antisense RNA 1 |