cloxacillin-7483 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the cloxacillin-7483 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AFF1 AF4/FMR2 family, member 1
AGGF1 angiogenic factor with G patch and FHA domains 1
AGMAT agmatine ureohydrolase (agmatinase)
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALPK1 alpha-kinase 1
APC adenomatous polyposis coli
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BCL3 B-cell CLL/lymphoma 3
C2ORF68 chromosome 2 open reading frame 68
CA5BP1 carbonic anhydrase VB pseudogene 1
CACTIN cactin, spliceosome C complex subunit
CAPN9 calpain 9
CDC25C cell division cycle 25C
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDON cell adhesion associated, oncogene regulated
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CTAGE5 CTAGE family, member 5
CTC1 CTS telomere maintenance complex component 1
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DMC1 DNA meiotic recombinase 1
ECE1 endothelin converting enzyme 1
EIF5B eukaryotic translation initiation factor 5B
ELSPBP1 epididymal sperm binding protein 1
FAM65A family with sequence similarity 65, member A
FANCE Fanconi anemia, complementation group E
FBXO31 F-box protein 31
FGFR4 fibroblast growth factor receptor 4
FLJ11710 uncharacterized protein FLJ11710
FLJ22184
FLOT1 flotillin 1
FOXG1 forkhead box G1
GK glycerol kinase
GPR137 G protein-coupled receptor 137
HCRP1 hepatocellular carcinoma-related HCRP1
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HLA-C major histocompatibility complex, class I, C
HNF4A hepatocyte nuclear factor 4, alpha
IRS2 insulin receptor substrate 2
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCTD2 potassium channel tetramerization domain containing 2
KLHL22 kelch-like family member 22
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MBNL2 muscleblind-like splicing regulator 2
MBOAT7 membrane bound O-acyltransferase domain containing 7
MCF2L MCF.2 cell line derived transforming sequence-like
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MYO1E myosin IE
NIPAL2 NIPA-like domain containing 2
NOP14-AS1 NOP14 antisense RNA 1
NPTXR neuronal pentraxin receptor
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NUP54 nucleoporin 54kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
ONECUT2 one cut homeobox 2
OSGIN1 oxidative stress induced growth inhibitor 1
PARD6B par-6 family cell polarity regulator beta
PAX9 paired box 9
PCNX pecanex homolog (Drosophila)
PDCL phosducin-like
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PSAT1 phosphoserine aminotransferase 1
PSD4 pleckstrin and Sec7 domain containing 4
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTRF polymerase I and transcript release factor
RAB27B RAB27B, member RAS oncogene family
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RND2 Rho family GTPase 2
RNF122 ring finger protein 122
RNF39 ring finger protein 39
RPL35A ribosomal protein L35a
RTEL1 regulator of telomere elongation helicase 1
RUFY3 RUN and FYVE domain containing 3
SEC14L1 SEC14-like 1 (S. cerevisiae)
SETD1A SET domain containing 1A
SH2D4A SH2 domain containing 4A
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SP100 SP100 nuclear antigen
STX1A syntaxin 1A (brain)
SYT17 synaptotagmin XVII
TFF2 trefoil factor 2
TICAM1 toll-like receptor adaptor molecule 1
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TTC9 tetratricopeptide repeat domain 9
TXNL4A thioredoxin-like 4A
TYMS thymidylate synthetase
USP34 ubiquitin specific peptidase 34
VASH2 vasohibin 2
WNT16 wingless-type MMTV integration site family, member 16
ZCCHC24 zinc finger, CCHC domain containing 24
ZFX zinc finger protein, X-linked
ZNF10 zinc finger protein 10
ZNF423 zinc finger protein 423
ZNF432 zinc finger protein 432
ZNF747 zinc finger protein 747
ZNF783 zinc finger family member 783
ZNF787 zinc finger protein 787

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
AFF4 AF4/FMR2 family, member 4
AMT aminomethyltransferase
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARID4A AT rich interactive domain 4A (RBP1-like)
AVPI1 arginine vasopressin-induced 1
BCORL1 BCL6 corepressor-like 1
BPGM 2,3-bisphosphoglycerate mutase
BRAF B-Raf proto-oncogene, serine/threonine kinase
C11ORF30 chromosome 11 open reading frame 30
C16ORF45 chromosome 16 open reading frame 45
C17ORF70 chromosome 17 open reading frame 70
C17ORF80 chromosome 17 open reading frame 80
CAPN5 calpain 5
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC92 coiled-coil domain containing 92
CCNO cyclin O
CNGB3 cyclic nucleotide gated channel beta 3
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRYBG3 beta-gamma crystallin domain containing 3
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DGKE diacylglycerol kinase, epsilon 64kDa
DMTN dematin actin binding protein
EDAR ectodysplasin A receptor
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
ERCC4 excision repair cross-complementation group 4
FBXL2 F-box and leucine-rich repeat protein 2
FBXO46 F-box protein 46
FKBP10 FK506 binding protein 10, 65 kDa
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GPR27 G protein-coupled receptor 27
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIST1H1E histone cluster 1, H1e
HIST1H4D histone cluster 1, H4d
HIST1H4F histone cluster 1, H4f
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
IGFLR1 IGF-like family receptor 1
IL15RA interleukin 15 receptor, alpha
IRF6 interferon regulatory factor 6
KLHL28 kelch-like family member 28
LGALS4 lectin, galactoside-binding, soluble, 4
LINS lines homolog (Drosophila)
LPXN leupaxin
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRP3 low density lipoprotein receptor-related protein 3
LY6D lymphocyte antigen 6 complex, locus D
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MBNL3 muscleblind-like splicing regulator 3
MPI mannose phosphate isomerase
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MYO1F myosin IF
NACA2 nascent polypeptide-associated complex alpha subunit 2
NEK11 NIMA-related kinase 11
NT5C 5', 3'-nucleotidase, cytosolic
OXTR oxytocin receptor
PAIP2B poly(A) binding protein interacting protein 2B
PC pyruvate carboxylase
PCDHGB5 protocadherin gamma subfamily B, 5
PDGFRL platelet-derived growth factor receptor-like
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PGR progesterone receptor
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PNPLA6 patatin-like phospholipase domain containing 6
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PQLC1 PQ loop repeat containing 1
RIC8B RIC8 guanine nucleotide exchange factor B
RNF170 ring finger protein 170
RNF25 ring finger protein 25
RPAP2 RNA polymerase II associated protein 2
RPL23AP32 ribosomal protein L23a pseudogene 32
RPUSD2 RNA pseudouridylate synthase domain containing 2
SCN1B sodium channel, voltage gated, type I beta subunit
SIRT6 sirtuin 6
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SREK1IP1 SREK1-interacting protein 1
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SUSD4 sushi domain containing 4
TESK1 testis-specific kinase 1
TESK2 testis-specific kinase 2
TMPRSS4 transmembrane protease, serine 4
TMSB15A thymosin beta 15a
UBQLN4 ubiquilin 4
VGF VGF nerve growth factor inducible
WDR62 WD repeat domain 62
ZBTB39 zinc finger and BTB domain containing 39
ZFP69B ZFP69 zinc finger protein B
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF189 zinc finger protein 189
ZNF248 zinc finger protein 248
ZNF480 zinc finger protein 480
ZXDC ZXD family zinc finger C