clotrimazole-905 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the clotrimazole-905 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
AKAP9 A kinase (PRKA) anchor protein 9
ANG angiogenin, ribonuclease, RNase A family, 5
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ATAT1 alpha tubulin acetyltransferase 1
ATF3 activating transcription factor 3
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2
CACYBP calcyclin binding protein
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COL3A1 collagen, type III, alpha 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
CSNK1G1 casein kinase 1, gamma 1
CSPP1 centrosome and spindle pole associated protein 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAH3 dynein, axonemal, heavy chain 3
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP10 dual specificity phosphatase 10
EGR1 early growth response 1
ESR1 estrogen receptor 1
FGFR2 fibroblast growth factor receptor 2
FLOT1 flotillin 1
FNDC3A fibronectin type III domain containing 3A
GLRX glutaredoxin (thioltransferase)
GPR87 G protein-coupled receptor 87
GSPT1 G1 to S phase transition 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HFE hemochromatosis
HIST1H4H histone cluster 1, H4h
HRASLS2 HRAS-like suppressor 2
INHBE inhibin, beta E
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGB5 integrin, beta 5
JUN jun proto-oncogene
KAT6B K(lysine) acetyltransferase 6B
KIAA0513 KIAA0513
KIZ kizuna centrosomal protein
KLF4 Kruppel-like factor 4 (gut)
KLF9 Kruppel-like factor 9
KLHL24 kelch-like family member 24
LHX6 LIM homeobox 6
LNPEP leucyl/cystinyl aminopeptidase
LRRC40 leucine rich repeat containing 40
LZTFL1 leucine zipper transcription factor-like 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP1B microtubule-associated protein 1B
MBNL2 muscleblind-like splicing regulator 2
MITF microphthalmia-associated transcription factor
NFIL3 nuclear factor, interleukin 3 regulated
NUP62CL nucleoporin 62kDa C-terminal like
OSGIN1 oxidative stress induced growth inhibitor 1
OVGP1 oviductal glycoprotein 1, 120kDa
PDCD2 programmed cell death 2
PDE12 phosphodiesterase 12
PDLIM5 PDZ and LIM domain 5
PGM3 phosphoglucomutase 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLCH1 phospholipase C, eta 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PSEN2 presenilin 2
PSPH phosphoserine phosphatase
RAB11B RAB11B, member RAS oncogene family
RASA2 RAS p21 protein activator 2
RIOK3 RIO kinase 3
RNASE4 ribonuclease, RNase A family, 4
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPS2 ribosomal protein S2
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SEC24D SEC24 family member D
SIK3 SIK family kinase 3
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SOX9 SRY (sex determining region Y)-box 9
SPATA1 spermatogenesis associated 1
SPRED2 sprouty-related, EVH1 domain containing 2
SRCAP Snf2-related CREBBP activator protein
STK11 serine/threonine kinase 11
SUGP1 SURP and G patch domain containing 1
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TES testin LIM domain protein
TREX1 three prime repair exonuclease 1
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor
VPRBP Vpr (HIV-1) binding protein
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF589 zinc finger protein 589
ZNF814 zinc finger protein 814

decreased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADRA2C adrenoceptor alpha 2C
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANKFY1 ankyrin repeat and FYVE domain containing 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BMP4 bone morphogenetic protein 4
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C2ORF44 chromosome 2 open reading frame 44
C5AR2 complement component 5a receptor 2
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CALCOCO1 calcium binding and coiled-coil domain 1
CCNT1 cyclin T1
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CIR1 corepressor interacting with RBPJ, 1
CRIP1 cysteine-rich protein 1 (intestinal)
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DMTN dematin actin binding protein
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ERCC4 excision repair cross-complementation group 4
FBRS fibrosin
FBXW12 F-box and WD repeat domain containing 12
FLT4 fms-related tyrosine kinase 4
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GLTP glycolipid transfer protein
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
HAUS6 HAUS augmin-like complex, subunit 6
HIST1H2AM histone cluster 1, H2am
HOXC8 homeobox C8
HSPA2 heat shock 70kDa protein 2
IPP intracisternal A particle-promoted polypeptide
KAT2A K(lysine) acetyltransferase 2A
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KDM5C lysine (K)-specific demethylase 5C
KLHL26 kelch-like family member 26
KRT15 keratin 15, type I
KRT8P12 keratin 8 pseudogene 12
LRP3 low density lipoprotein receptor-related protein 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAP1S microtubule-associated protein 1S
MATN2 matrilin 2
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MFAP2 microfibrillar-associated protein 2
MIS18BP1 MIS18 binding protein 1
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MSL1 male-specific lethal 1 homolog (Drosophila)
NAP1L2 nucleosome assembly protein 1-like 2
NDE1 nudE neurodevelopment protein 1
NLRX1 NLR family member X1
NPY1R neuropeptide Y receptor Y1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PALM paralemmin
PARD6A par-6 family cell polarity regulator alpha
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PELI1 pellino E3 ubiquitin protein ligase 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PMP22 peripheral myelin protein 22
PODXL2 podocalyxin-like 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBL1 retinoblastoma-like 1
RECQL4 RecQ protein-like 4
RFTN1 raftlin, lipid raft linker 1
RIPK4 receptor-interacting serine-threonine kinase 4
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RWDD3 RWD domain containing 3
SCN1B sodium channel, voltage gated, type I beta subunit
SETD1A SET domain containing 1A
SH2D4A SH2 domain containing 4A
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TM7SF3 transmembrane 7 superfamily member 3
TMEM183A transmembrane protein 183A
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBQLN4 ubiquilin 4
UNC119 unc-119 homolog (C. elegans)
USB1 U6 snRNA biogenesis 1
VEGFC vascular endothelial growth factor C
VWA1 von Willebrand factor A domain containing 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZDHHC18 zinc finger, DHHC-type containing 18
ZFP30 ZFP30 zinc finger protein
ZNF212 zinc finger protein 212
ZNF281 zinc finger protein 281
ZNF510 zinc finger protein 510
ZNF76 zinc finger protein 76
ZNF813 zinc finger protein 813