clotrimazole-3166 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the clotrimazole-3166 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM12 ADAM metallopeptidase domain 12
ADAM23 ADAM metallopeptidase domain 23
ALOX15B arachidonate 15-lipoxygenase, type B
AMOT angiomotin
APOC4 apolipoprotein C-IV
APP amyloid beta (A4) precursor protein
ARHGAP26 Rho GTPase activating protein 26
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BIRC7 baculoviral IAP repeat containing 7
C10ORF95 chromosome 10 open reading frame 95
C1ORF68 chromosome 1 open reading frame 68
C2CD2L C2CD2-like
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAPN9 calpain 9
CD7 CD7 molecule
CDC25C cell division cycle 25C
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CGA glycoprotein hormones, alpha polypeptide
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLEC3B C-type lectin domain family 3, member B
CLEC4A C-type lectin domain family 4, member A
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DUSP9 dual specificity phosphatase 9
EPHB2 EPH receptor B2
FBXL7 F-box and leucine-rich repeat protein 7
FCAR Fc fragment of IgA receptor
FES FES proto-oncogene, tyrosine kinase
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
GJB3 gap junction protein, beta 3, 31kDa
GPR15 G protein-coupled receptor 15
GRIK2 glutamate receptor, ionotropic, kainate 2
HAB1 B1 for mucin
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
IGHA1 immunoglobulin heavy constant alpha 1
IMPG2 interphotoreceptor matrix proteoglycan 2
INHBC inhibin, beta C
INHBE inhibin, beta E
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JAK2 Janus kinase 2
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIAA0040 KIAA0040
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KLHL18 kelch-like family member 18
KRT15 keratin 15, type I
LIF leukemia inhibitory factor
LOC644450 uncharacterized LOC644450
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MEOX1 mesenchyme homeobox 1
MOCS1 molybdenum cofactor synthesis 1
MTMR3 myotubularin related protein 3
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC6 mucin 6, oligomeric mucus/gel-forming
MYOF myoferlin
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NIPAL3 NIPA-like domain containing 3
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPR3 natriuretic peptide receptor 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OSMR oncostatin M receptor
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PSD4 pleckstrin and Sec7 domain containing 4
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PXDC1 PX domain containing 1
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RERE arginine-glutamic acid dipeptide (RE) repeats
RNASE4 ribonuclease, RNase A family, 4
RORC RAR-related orphan receptor C
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SAMD4A sterile alpha motif domain containing 4A
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SERHL2 serine hydrolase-like 2
SIRT5 sirtuin 5
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
STX7 syntaxin 7
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TFF2 trefoil factor 2
TOP3B topoisomerase (DNA) III beta
TRAV8-3 T cell receptor alpha variable 8-3
TSC22D2 TSC22 domain family, member 2
UPK2 uroplakin 2
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
WIPF1 WAS/WASL interacting protein family, member 1
WIPI1 WD repeat domain, phosphoinositide interacting 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZNF419 zinc finger protein 419
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
AFAP1 actin filament associated protein 1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
C2ORF27A chromosome 2 open reading frame 27A
CCNK cyclin K
CCNO cyclin O
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CHRM3 cholinergic receptor, muscarinic 3
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CNGB3 cyclic nucleotide gated channel beta 3
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DOC2A double C2-like domains, alpha
DTX4 deltex 4, E3 ubiquitin ligase
EDAR ectodysplasin A receptor
EPHA2 EPH receptor A2
EXD3 exonuclease 3'-5' domain containing 3
FAM189A2 family with sequence similarity 189, member A2
FLCN folliculin
GDAP1 ganglioside induced differentiation associated protein 1
GLTP glycolipid transfer protein
GPC4 glypican 4
GPX2 glutathione peroxidase 2
GRB7 growth factor receptor-bound protein 7
HIRA histone cell cycle regulator
HIST1H2AL histone cluster 1, H2al
HMOX1 heme oxygenase 1
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXC5 homeobox C5
HOXC8 homeobox C8
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IDI2-AS1 IDI2 antisense RNA 1
IFI35 interferon-induced protein 35
IL17RB interleukin 17 receptor B
INCENP inner centromere protein antigens 135/155kDa
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM8 lysine (K)-specific demethylase 8
KIF13B kinesin family member 13B
KLF2 Kruppel-like factor 2
LDHB lactate dehydrogenase B
LIN7A lin-7 homolog A (C. elegans)
LMNB1 lamin B1
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRRC49 leucine rich repeat containing 49
LYZ lysozyme
MATK megakaryocyte-associated tyrosine kinase
MBTPS2 membrane-bound transcription factor peptidase, site 2
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MED9 mediator complex subunit 9
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MPO myeloperoxidase
MYO1F myosin IF
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NLRX1 NLR family member X1
NOL12 nucleolar protein 12
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NT5E 5'-nucleotidase, ecto (CD73)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PARD6A par-6 family cell polarity regulator alpha
PHC1 polyhomeotic homolog 1 (Drosophila)
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PPT2 palmitoyl-protein thioesterase 2
PTPRE protein tyrosine phosphatase, receptor type, E
QSER1 glutamine and serine rich 1
RAB4B RAB4B, member RAS oncogene family
RASAL1 RAS protein activator like 1 (GAP1 like)
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SCAI suppressor of cancer cell invasion
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOWAHC sosondowah ankyrin repeat domain family member C
SRGN serglycin
SYCP2 synaptonemal complex protein 2
TAOK1 TAO kinase 1
THRAP3 thyroid hormone receptor associated protein 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
UNC119 unc-119 homolog (C. elegans)
USP19 ubiquitin specific peptidase 19
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDR76 WD repeat domain 76
ZCCHC6 zinc finger, CCHC domain containing 6
ZNF180 zinc finger protein 180
ZNF219 zinc finger protein 219
ZNF34 zinc finger protein 34
ZNF428 zinc finger protein 428
ZNF446 zinc finger protein 446
ZNF74 zinc finger protein 74