cloperastine-4271 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the cloperastine-4271 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ATN1 atrophin 1
BIRC3 baculoviral IAP repeat containing 3
BRSK2 BR serine/threonine kinase 2
C1ORF116 chromosome 1 open reading frame 116
C21ORF2 chromosome 21 open reading frame 2
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CADM1 cell adhesion molecule 1
CADM3 cell adhesion molecule 3
CALR calreticulin
CCDC64 coiled-coil domain containing 64
CCL27 chemokine (C-C motif) ligand 27
CD7 CD7 molecule
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CDHR2 cadherin-related family member 2
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHODL chondrolectin
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CST4 cystatin S
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL8 chemokine (C-X-C motif) ligand 8
CYR61 cysteine-rich, angiogenic inducer, 61
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DENND3 DENN/MADD domain containing 3
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EPOR erythropoietin receptor
FOSL2 FOS-like antigen 2
FSCN3 fascin actin-bundling protein 3, testicular
FXYD2 FXYD domain containing ion transport regulator 2
GADD45B growth arrest and DNA-damage-inducible, beta
GATA4 GATA binding protein 4
GREB1L growth regulation by estrogen in breast cancer-like
GTPBP1 GTP binding protein 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2BO histone cluster 1, H2bo
HNF1A HNF1 homeobox A
HNMT histamine N-methyltransferase
HYOU1 hypoxia up-regulated 1
ICAM2 intercellular adhesion molecule 2
IL22RA1 interleukin 22 receptor, alpha 1
IL6 interleukin 6
INHBA inhibin, beta A
INPP5J inositol polyphosphate-5-phosphatase J
IRF4 interferon regulatory factor 4
JUND jun D proto-oncogene
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KHSRP KH-type splicing regulatory protein
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KLHL25 kelch-like family member 25
KYNU kynureninase
LAT2 linker for activation of T cells family, member 2
LIF leukemia inhibitory factor
LMO2 LIM domain only 2 (rhombotin-like 1)
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LTBP4 latent transforming growth factor beta binding protein 4
MATN1 matrilin 1, cartilage matrix protein
MBD2 methyl-CpG binding domain protein 2
MT1F metallothionein 1F
MT1M metallothionein 1M
MUC4 mucin 4, cell surface associated
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NNAT neuronatin
NUPR1 nuclear protein, transcriptional regulator, 1
NYNRIN NYN domain and retroviral integrase containing
OPN1SW opsin 1 (cone pigments), short-wave-sensitive
PCDH1 protocadherin 1
PCGF2 polycomb group ring finger 2
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDIA4 protein disulfide isomerase family A, member 4
PHLDA1 pleckstrin homology-like domain, family A, member 1
PMFBP1 polyamine modulated factor 1 binding protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRAF2 PRA1 domain family, member 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRR protein tyrosine phosphatase, receptor type, R
PXDC1 PX domain containing 1
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RGS6 regulator of G-protein signaling 6
RND1 Rho family GTPase 1
RUNX1 runt-related transcription factor 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SDF2L1 stromal cell-derived factor 2-like 1
STC2 stanniocalcin 2
STEAP4 STEAP family member 4
TBX2 T-box 2
TEF thyrotrophic embryonic factor
TGFB2 transforming growth factor, beta 2
TGM4 transglutaminase 4
TLN1 talin 1
TP53I11 tumor protein p53 inducible protein 11
TRD T cell receptor delta locus
TRIB3 tribbles pseudokinase 3
TRIM3 tripartite motif containing 3
TRIO trio Rho guanine nucleotide exchange factor
ZFHX3 zinc finger homeobox 3

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AK5 adenylate kinase 5
ANKH ANKH inorganic pyrophosphate transport regulator
ANKRD36 ankyrin repeat domain 36
ARHGAP24 Rho GTPase activating protein 24
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BEX1 brain expressed, X-linked 1
C11ORF30 chromosome 11 open reading frame 30
C17ORF80 chromosome 17 open reading frame 80
CCDC88A coiled-coil domain containing 88A
CENPJ centromere protein J
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DCBLD2 discoidin, CUB and LCCL domain containing 2
DENND5B DENN/MADD domain containing 5B
DEPDC1 DEP domain containing 1
DNAL4 dynein, axonemal, light chain 4
E2F8 E2F transcription factor 8
EDIL3 EGF-like repeats and discoidin I-like domains 3
EHF ets homologous factor
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EYA4 EYA transcriptional coactivator and phosphatase 4
FGF23 fibroblast growth factor 23
FLRT3 fibronectin leucine rich transmembrane protein 3
FOXN2 forkhead box N2
FPGT fucose-1-phosphate guanylyltransferase
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GLTP glycolipid transfer protein
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GSTCD glutathione S-transferase, C-terminal domain containing
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HACD3 3-hydroxyacyl-CoA dehydratase 3
HAS2 hyaluronan synthase 2
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H2AM histone cluster 1, H2am
HIST1H2BJ histone cluster 1, H2bj
HIST1H4C histone cluster 1, H4c
HSPA2 heat shock 70kDa protein 2
IFI6 interferon, alpha-inducible protein 6
IFNA17 interferon, alpha 17
KIAA1549L KIAA1549-like
KIRREL kin of IRRE like (Drosophila)
KLF13 Kruppel-like factor 13
KLHL3 kelch-like family member 3
LOC100286895 cell division cycle 27 homolog pseudogene
LRP3 low density lipoprotein receptor-related protein 3
LRP4 low density lipoprotein receptor-related protein 4
LRRC23 leucine rich repeat containing 23
MAGEA6 melanoma antigen family A6
MAP3K2 mitogen-activated protein kinase kinase kinase 2
METTL16 methyltransferase like 16
MIS18BP1 MIS18 binding protein 1
NABP1 nucleic acid binding protein 1
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NR1D2 nuclear receptor subfamily 1, group D, member 2
PACS1 phosphofurin acidic cluster sorting protein 1
PALMD palmdelphin
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PMCH pro-melanin-concentrating hormone
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRR14L proline rich 14-like
PWAR5 Prader Willi/Angelman region RNA 5
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RBBP5 retinoblastoma binding protein 5
RFX7 regulatory factor X, 7
RSRC1 arginine/serine-rich coiled-coil 1
S100A4 S100 calcium binding protein A4
SCD5 stearoyl-CoA desaturase 5
SCUBE3 signal peptide, CUB domain, EGF-like 3
SCYL2 SCY1-like 2 (S. cerevisiae)
SDC3 syndecan 3
SIGLEC15 sialic acid binding Ig-like lectin 15
SMAD5 SMAD family member 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNORA21 small nucleolar RNA, H/ACA box 21
SPIN1 spindlin 1
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TENM4 teneurin transmembrane protein 4
TIPRL TOR signaling pathway regulator
TMEM209 transmembrane protein 209
TRIM9 tripartite motif containing 9
VASH2 vasohibin 2
VGLL3 vestigial-like family member 3
ZNF124 zinc finger protein 124
ZNF350 zinc finger protein 350
ZNF669 zinc finger protein 669
ZWILCH zwilch kinetochore protein